Click Chemistry Assisted Single-Molecule Fingerprinting Reveals a 3D Biomolecular Folding Funnel

2012 ◽  
Vol 134 (30) ◽  
pp. 12338-12341 ◽  
Author(s):  
Zhongbo Yu ◽  
Deepak Koirala ◽  
Yunxi Cui ◽  
Leah F. Easterling ◽  
Yuan Zhao ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Single Molecule

scholarly journals Dual Unnatural Amino Acid Incorporation and Click-Chemistry Labeling to Enable Single-Molecule FRET Studies of p97 Folding

ChemBioChem ◽  
2016 ◽  
Vol 17 (11) ◽  
pp. 981-984 ◽  
Author(s):  
Taehyung C. Lee ◽  
Minjin Kang ◽  
Chan Hyuk Kim ◽  
Peter G. Schultz ◽  
Eli Chapman ◽  
...  
Keyword(s):  
Amino Acid ◽  
Click Chemistry ◽  
Single Molecule ◽  
Unnatural Amino Acid ◽  
Amino Acid Incorporation ◽  
Single Molecule Fret ◽  
Acid Incorporation

From the molecule to the mole: improving heterogeneous copper catalyzed click chemistry using single molecule spectroscopy

2017 ◽  
Vol 53 (2) ◽  
pp. 328-331 ◽  
Author(s):  
Bowen Wang ◽  
Javier Durantini ◽  
Matthew R. Decan ◽  
Jun Nie ◽  
Anabel E. Lanterna ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Single Molecule ◽  
Single Molecule Spectroscopy

scholarly journals Single-Molecule Orthogonal Double-Click Chemistry—Inorganic to Organic Nanostructure Transition

2020 ◽  
Vol 12 (24) ◽  
pp. 27737-27744
Author(s):  
Barry Arkles ◽  
Jonathan Goff ◽  
Taewoo Min ◽  
Youlin Pan ◽  
Alison Phillips ◽  
...  
Keyword(s):  
Click Chemistry ◽  
Single Molecule ◽  
Organic Nanostructure

scholarly journals Click Chemistry: Mechanistic Insights into the Role of Amines Using Single-Molecule Spectroscopy

ACS Catalysis ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. 8487-8492 ◽  
Author(s):  
Bowen Wang ◽  
Anabel E. Lanterna ◽  
Juan C. Scaiano
Keyword(s):  
Click Chemistry ◽  
Single Molecule ◽  
Single Molecule Spectroscopy

The method of replication affects metal film granularity and resolution

1989 ◽  
Vol 47 ◽  
pp. 708-709
Author(s):  
George C. Ruben
Keyword(s):  
Electron Beam ◽  
High Resolution ◽  
Film Thickness ◽  
Single Molecule ◽  
Metal Film ◽  
Vertical Surface ◽  
High Resolution Imaging ◽  
Controllable Factors ◽  
Resolution Imaging

Single molecule resolution in electron beam sensitive, uncoated, noncrystalline materials has been impossible except in thin Pt-C replicas ≤ 150Å) which are resistant to the electron beam destruction. Previously the granularity of metal film replicas limited their resolution to ≥ 20Å. This paper demonstrates that Pt-C film granularity and resolution are a function of the method of replication and other controllable factors. Low angle 20° rotary , 45° unidirectional and vertical 9.7±1 Å Pt-C films deposited on mica under the same conditions were compared in Fig. 1. Vertical replication had a 5A granularity (Fig. 1c), the highest resolution (table), and coated the whole surface. 45° replication had a 9Å granulartiy (Fig. 1b), a slightly poorer resolution (table) and did not coat the whole surface. 20° rotary replication was unsuitable for high resolution imaging with 20-25Å granularity (Fig. 1a) and resolution 2-3 times poorer (table). Resolution is defined here as the greatest distance for which the metal coat on two opposing faces just grow together, that is, two times the apparent film thickness on a single vertical surface.

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