Monitoring the Electrochemistry of Single Molecules by Surface-Enhanced Raman Spectroscopy

2010 ◽  
Vol 132 (51) ◽  
pp. 18034-18037 ◽  
Author(s):  
Emiliano Cortés ◽  
Pablo G. Etchegoin ◽  
Eric C. Le Ru ◽  
Alejandro Fainstein ◽  
María E. Vela ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Single Molecules ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Surface-enhanced Raman spectroscopy of dyes: from single molecules to the artists’ canvas

2009 ◽  
Vol 11 (34) ◽  
pp. 7350 ◽  
Author(s):  
Kristin L. Wustholz ◽  
Christa L. Brosseau ◽  
Francesca Casadio ◽  
Richard P. Van Duyne
Keyword(s):  
Raman Spectroscopy ◽  
Single Molecules ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

scholarly journals Observing Single Molecules Complexing with Cucurbit[7]uril through Nanogap Surface-Enhanced Raman Spectroscopy

2016 ◽  
Vol 7 (4) ◽  
pp. 704-710 ◽  
Author(s):  
Daniel O. Sigle ◽  
Setu Kasera ◽  
Lars O. Herrmann ◽  
Aniello Palma ◽  
Bart de Nijs ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Single Molecules ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

Sign in / Sign up

Export Citation Format

Share Document