Computational Study of Thymine Dimer Radical Anion Splitting in the Self-Repair Process of Duplex DNA

2008 ◽  
Vol 130 (11) ◽  
pp. 3443-3450 ◽  
Author(s):  
Fanny Masson ◽  
Teodoro Laino ◽  
Ivano Tavernelli ◽  
Ursula Rothlisberger ◽  
Jürg Hutter
2007 ◽  
Vol 129 (1) ◽  
pp. 6-7 ◽  
Author(s):  
Matthew Ray Holman ◽  
Takeo Ito ◽  
Steven E. Rokita
Keyword(s):  

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Bo Wu ◽  
Chan Zhang ◽  
Bo Chen ◽  
Ling Zhang ◽  
Ruchun Dai ◽  
...  

Bone microdamage can be repaired through bone remodeling induced by loading. In this study, a loading device was developed for improved efficiency and the self-repair process of bone microdamage was studied in ovariectomized rats. First, four-point bending fixtures capable of holding two live rats simultaneously were designed. Rats were loaded and subjected to a sinusoidal wave for 10,000 cycles. They were then divided into four groups to evaluate time points from 1 to 4 weeks in the microdamage repair process. The loaded right ulna was used for microdamage parameter analysis, and the loaded right radius was tested for mechanical properties. In all groups, microdamage consisted primarily of microcracks, which were observed in bone surrounding the force-bearing point. The values of the microdamage parameters were significantly lower at 3 weeks than at 2 weeks. However, none of the differences in mechanical properties between any four groups were statistically significant. This study shows that the improved application of loading in the form of bending for double-rat simultaneous administration was practical and efficient. These results suggest that microdamage was repaired between 2 weeks to 3 weeks after fatigue damage and microdamage is a more sensitive index of bone quality than mechanical properties.


ChemPhysChem ◽  
2009 ◽  
Vol 10 (2) ◽  
pp. 400-410 ◽  
Author(s):  
Fanny Masson ◽  
Teodoro Laino ◽  
Ursula Rothlisberger ◽  
Jürg Hutter

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Li Sun ◽  
Dezhi Liang ◽  
Qianqian Gao ◽  
Jianhong Zhou

Crack expansion of concrete is the initial damage stage of structures, which may cause greater damage to structures subject to long-term loads or under extreme conditions. In recent years, the application of intelligent materials to crack self-repair has become a hotspot among researchers. In order to study the influence of factors on the self-repair capability of shape memory alloy (SMA) wire concrete beam, both theoretical and experimental methods were employed for analysis. For the convenience of experiment, composite materials (epoxy cement mortar and silicone polymer clay) instead of concrete were used. The SMA wires were externally installed on and internally embedded in epoxy resin cement mortar beams and silicone polymer clay beams. Comparison of crack repair situation between two installation methods turns out that both methods possess their own advantages and disadvantages and should be employed according to the actual situation. The influence of unbonded length on the self-repair capability of embedded type SMA wire beams and the necessary minimum unbonded length to achieve self-repair function were studied. The results state clearly that the longer the unbonded length is, the better the crack repair situation is.


2014 ◽  
Vol 136 (42) ◽  
pp. 14801-14810 ◽  
Author(s):  
Hideo Ando ◽  
Benjamin P. Fingerhut ◽  
Konstantin E. Dorfman ◽  
Jason D. Biggs ◽  
Shaul Mukamel

2011 ◽  
Author(s):  
Alexander J. Cushman ◽  
Brian C. Fehrman ◽  
Umesh A. Korde

2007 ◽  
Vol 1 (10) ◽  
pp. 1186-1196
Author(s):  
Yutaka TOI ◽  
Satoshi HIROSE
Keyword(s):  

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