A Practical Method for Enantioselective Synthesis of All-Carbon Quaternary Stereogenic Centers through NHC-Cu-Catalyzed Conjugate Additions of Alkyl- and Arylzinc Reagents to β-Substituted Cyclic Enones

2006 ◽  
Vol 128 (22) ◽  
pp. 7182-7184 ◽  
Author(s):  
Kang-sang Lee ◽  
M. Kevin Brown ◽  
Alexander W. Hird ◽  
Amir H. Hoveyda
Keyword(s):  
Practical Method ◽  
Enantioselective Synthesis ◽  
Conjugate Additions ◽  
Stereogenic Centers ◽  
Cyclic Enones ◽  
Quaternary Stereogenic Centers

scholarly journals Enantioselective synthesis of gem-diarylalkanes by transition metal-catalyzed asymmetric arylations (TMCAAr)

2018 ◽  
Vol 9 (3) ◽  
pp. 546-559 ◽  
Author(s):  
Tao Jia ◽  
Peng Cao ◽  
Jian Liao
Keyword(s):  
Transition Metal ◽  
Enantioselective Synthesis ◽  
Transfer Reactions ◽  
Stereogenic Centers ◽  
Transition Metal Catalyzed ◽  
Metal Catalyzed ◽  
Quaternary Stereogenic Centers ◽  
Aryl Transfer

To date, enantiomerically enriched molecules containing gem(1,1)-diaryl containing tertiary or quaternary stereogenic centers have been readily accessed by transition metal-catalyzed enantioselective or stereoconvergent aryl transfer reactions.

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