Studies on Lignin and Related Compounds. LIX. Aromatic Aldehydes from Plant Materials

1941 ◽  
Vol 63 (11) ◽  
pp. 3049-3052 ◽  
Author(s):  
R. H. J. Creighton ◽  
Joseph L. McCarthy ◽  
Harold Hibbert
Pathogens ◽  
2020 ◽  
Vol 9 (7) ◽  
pp. 542 ◽  
Author(s):  
John J. Mackrill ◽  
Roberta A. Kehoe ◽  
Limian Zheng ◽  
Mary L. McKee ◽  
Elaine C. O’Sullivan ◽  
...  

The pathogen Phytophthora infestans is responsible for catastrophic crop damage on a global scale which totals billions of euros annually. The discovery of new inhibitors of this organism is of paramount agricultural importance and of critical relevance to food security. Current strategies for crop treatment are inadequate with the emergence of resistant strains and problematic toxicity. Natural products such as cinnamaldehyde have been reported to have fungicidal properties and are the seed for many new discovery research programmes. We report a probe of the cinnamaldehyde framework to investigate the aldehyde subunit and its role in a subset of aromatic aldehydes in order to identify new lead compounds to act against P. infestans. An ellipticine derivative which incorporates an aldehyde (9-formyl-6-methyl ellipticine, 34) has been identified with exceptional activity versus P. infestans with limited toxicity and potential for use as a fungicide.


1992 ◽  
Vol 31 (2) ◽  
pp. 515-517 ◽  
Author(s):  
Yoshiaki Noma ◽  
Etsuko Akehi ◽  
Naoko Miki ◽  
Yoshinori Asakawa

1991 ◽  
Vol 30 (9) ◽  
pp. 2969-2972 ◽  
Author(s):  
Yoshiaki Noma ◽  
Yoko Okajima ◽  
Hironobu Takahashi ◽  
Yoshinori Asakawa

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