Carbon Syntheses with Malonic Acid and Related Compounds. II. Aromatic Aldehydes

1936 ◽  
Vol 58 (4) ◽  
pp. 680-684 ◽  
Author(s):  
Arthur Michael ◽  
Nathan Weiner
Keyword(s):  
Malonic Acid ◽  
Aromatic Aldehydes ◽  
Related Compounds

ChemInform Abstract: Stereoselective Synthesis of Dehydroamino Acids Using Malonic Acid Half Oxyester and Aromatic Aldehydes.

ChemInform ◽  
2016 ◽  
Vol 47 (34) ◽  
Author(s):  
Yuttapong Singjunla ◽  
Silvia Colombano ◽  
Jerome Baudoux ◽  
Jacques Rouden
Keyword(s):  
Malonic Acid ◽  
Stereoselective Synthesis ◽  
Aromatic Aldehydes ◽  
Dehydroamino Acids

scholarly journals Inhibitory Properties of Aldehydes and Related Compounds against Phytophthora infestans—Identification of a New Lead

Pathogens ◽  
2020 ◽  
Vol 9 (7) ◽  
pp. 542 ◽  
Author(s):  
John J. Mackrill ◽  
Roberta A. Kehoe ◽  
Limian Zheng ◽  
Mary L. McKee ◽  
Elaine C. O’Sullivan ◽  
...  
Keyword(s):  
Phytophthora Infestans ◽  
Aromatic Aldehydes ◽  
Global Scale ◽  
Crop Damage ◽  
Lead Compounds ◽  
Discovery Research ◽  
Research Programmes ◽  
Resistant Strains ◽  
Related Compounds ◽  
New Discovery

The pathogen Phytophthora infestans is responsible for catastrophic crop damage on a global scale which totals billions of euros annually. The discovery of new inhibitors of this organism is of paramount agricultural importance and of critical relevance to food security. Current strategies for crop treatment are inadequate with the emergence of resistant strains and problematic toxicity. Natural products such as cinnamaldehyde have been reported to have fungicidal properties and are the seed for many new discovery research programmes. We report a probe of the cinnamaldehyde framework to investigate the aldehyde subunit and its role in a subset of aromatic aldehydes in order to identify new lead compounds to act against P. infestans. An ellipticine derivative which incorporates an aldehyde (9-formyl-6-methyl ellipticine, 34) has been identified with exceptional activity versus P. infestans with limited toxicity and potential for use as a fungicide.

Triethylamine: a potential N-base surrogate for pyridine in Knoevenagel condensation of aromatic aldehydes and malonic acid

2016 ◽  
Vol 40 (6) ◽  
pp. 4962-4968 ◽  
Author(s):  
Hitesh S. Pawar ◽  
Adhirath S. Wagh ◽  
Arvind M. Lali
Keyword(s):  
Malonic Acid ◽  
Knoevenagel Condensation ◽  
Aromatic Aldehydes ◽  
Product Yield ◽  
Cinnamic Acids ◽  
Triethyl Amine

Triethyl amine was successfully examined as a potent N-base surrogate for Knoevenagel condensation to produce cinnamic acids without compromising product yield.

ChemInform Abstract: Solvent-Free Bentonite-Catalyzed Condensation of Malonic Acid and Aromatic Aldehydes under Microwave Irradiation.

ChemInform ◽  
2010 ◽  
Vol 32 (50) ◽  
pp. no-no
Author(s):  
Andre Loupy ◽  
Suk-Jin Song ◽  
Sun-Mee Soh ◽  
Yong-Mee Lee ◽  
Tae-Woo Kwon
Keyword(s):  
Microwave Irradiation ◽  
Malonic Acid ◽  
Aromatic Aldehydes ◽  
Solvent Free
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