Mechanism of action of coenzyme B12. Hydrogen transfer in the isomerization of methylmalonyl coenzyme A to succinyl coenzyme A

1969 ◽  
Vol 91 (6) ◽  
pp. 1498-1507 ◽  
Author(s):  
William Walter Miller ◽  
John Hall Richards
Keyword(s):  
Mechanism Of Action ◽  
Hydrogen Transfer ◽  
Coenzyme A ◽  
Coenzyme B12

Mechanism of action of coenzyme B12. Hydrogen transfer in the isomerization of .beta.-methylaspartate to glutamate

Biochemistry ◽  
1972 ◽  
Vol 11 (2) ◽  
pp. 253-264 ◽  
Author(s):  
R. G. Eagar ◽  
B. G. Baltimore ◽  
M. M. Herbst ◽  
H. A. Barker ◽  
J. H. Richards
Keyword(s):  
Mechanism Of Action ◽  
Hydrogen Transfer ◽  
Coenzyme B12

scholarly journals Studies on the Mechanism of Action of Coenzyme B12

1972 ◽  
Vol 247 (13) ◽  
pp. 4197-4207
Author(s):  
Thomas H. Finlay ◽  
Jay Valinsky ◽  
Kazuyoshi Sato ◽  
Robert H. Abeles
Keyword(s):  
Mechanism Of Action ◽  
Coenzyme B12

scholarly journals Mechanism of Action of a 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitor on Apolipoprotein B-100 Kinetics in Visceral Obesity

2002 ◽  
Vol 87 (5) ◽  
pp. 2283-2289 ◽  
Author(s):  
Dick C. Chan ◽  
Gerald F. Watts ◽  
P. Hugh R. Barrett ◽  
Trevor A. Mori ◽  
Lawrence J. Beilin ◽  
...  
Keyword(s):  
Mechanism Of Action ◽  
Apolipoprotein B ◽  
Reductase Inhibitor ◽  
Coenzyme A ◽  
Visceral Obesity ◽  
Coenzyme A Reductase

Anticancer auranofin engages 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) as a target

Metallomics ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 1925-1936 ◽  
Author(s):  
Songhai Tian ◽  
Fung-Ming Siu ◽  
Chun-Nam Lok ◽  
Yi Man Eva Fung ◽  
Chi-Ming Che
Keyword(s):  
Mechanism Of Action ◽  
Coenzyme A ◽  
Subcellular Fractionation ◽  
Proteomics Analysis ◽  
Anticancer Mechanism ◽  
Fractionation Method ◽  
Novel Target ◽  
Coenzyme A Reductase

Subcellular fractionation method was used with HPLC-MS/MS technique for proteomics analysis to study the anticancer mechanism of action of auranofin. HMGCR is identified as a novel target of auranofin.

scholarly journals How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 å resolution

Structure ◽  
1996 ◽  
Vol 4 (3) ◽  
pp. 339-350 ◽  
Author(s):  
Filippo Mancia ◽  
Nicholas H Keep ◽  
Atsushi Nakagawa ◽  
Peter F Leadlay ◽  
Sean McSweeney ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Coenzyme A ◽  
Coenzyme B12
Sign in / Sign up

Export Citation Format

Share Document