Nuclear magnetic resonance studies of hemoproteins. III. Restricted rotation of a heme side chain methyl group in some ferric myoglobin complexes and its implication in van der Waals contact in the heme side chain environments

1974 ◽  
Vol 96 (23) ◽  
pp. 7365-7367 ◽  
Author(s):  
Isao Morishima ◽  
Tetsutaro Iizuka
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Van Der Waals ◽  
Side Chain ◽  
Methyl Group ◽  
Magnetic Resonance Studies ◽  
Restricted Rotation ◽  
Nuclear Magnetic

Nuclear magnetic resonance studies on the configurations and conformations of heterocyclic nitrosamines

1968 ◽  
Vol 46 (17) ◽  
pp. 2827-2833 ◽  
Author(s):  
Y. L. Chow ◽  
C. J. Colón
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Chemical Shifts ◽  
Methyl Group ◽  
Magnetic Resonance Studies ◽  
Rigid System ◽  
Nuclear Magnetic Resonance Spectra ◽  
Equatorial Proton ◽  
Configuration And Conformation ◽  
Nuclear Magnetic

The nuclear magnetic resonance spectra of various heterocyclic nitrosamines were studied in solution. A qualitative view of the long-range diamagnetic effects of a nitrosamino group is advanced and correlated with the chemical shifts of α-equatorial protons and the methyl group in those nitrosamines possessing a preferred conformation or a rigid system. The use of this correlation to decide the configuration and conformation of heterocyclic nitrosamines is discussed. A large chemical shift difference (ca. 3 p.p.m.) between a cis α-axial and a cis α-equatorial proton was noted.

scholarly journals Fungal Metabolism of Toluene: Monitoring of Fluorinated Analogs by 19F Nuclear Magnetic Resonance Spectroscopy

2001 ◽  
Vol 67 (3) ◽  
pp. 1030-1034 ◽  
Author(s):  
Francesc X. Prenafeta-Boldú ◽  
Dion M. A. M. Luykx ◽  
Jacques Vervoort ◽  
Jan A. M. de Bont
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Side Chain ◽  
Resonance Spectroscopy ◽  
Initial Oxidation ◽  
Methyl Group ◽  
Whole Cells ◽  
Cunninghamella Echinulata ◽  
Initial Conversion ◽  
Nuclear Magnetic

ABSTRACT We used isomeric fluorotoluenes as model substrates to study the catabolism of toluene by five deuteromycete fungi and one ascomycete fungus capable of growth on toluene as the sole carbon and energy source, as well as by two fungi (Cunninghamella echinulata and Aspergillus niger) that cometabolize toluene. Whole cells were incubated with 2-, 3-, and 4-fluorotoluene, and metabolites were characterized by 19F nuclear magnetic resonance. Oxidation of fluorotoluene by C. echinulata was initiated either at the aromatic ring, resulting in fluorinated o-cresol, or at the methyl group to form fluorobenzoate. The initial conversion of the fluorotoluenes by toluene-grown fungi occurred only at the side chain and resulted in fluorinated benzoates. The latter compounds were the substrate for the ring hydroxylation and, depending on the fluorine position, were further metabolized up to catecholic intermediates. From the19F nuclear magnetic resonance metabolic profiles, we propose that diverse fungi that grow on toluene assimilate toluene by an initial oxidation of the methyl group.

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