Structural characterization of tris(N,N-di-n-butyldithiocarbamato)nickel(IV) bromide. A Ni-S6 complex with unusual chemical properties

1970 ◽  
Vol 92 (23) ◽  
pp. 6972-6974 ◽  
Author(s):  
John P. Fackler ◽  
Alex. Avdeef ◽  
Robert G. Fischer
Keyword(s):  
Structural Characterization ◽  
Chemical Properties

scholarly journals Characterization of a Natural Dye by Spectroscopic and Chromatographic Techniques

2012 ◽  
Vol 1374 ◽  
pp. 49-59 ◽  
Author(s):  
Y. Espinosa-Morales ◽  
J. Reyes ◽  
B. Hermosín ◽  
J. A. Azamar-Barrios
Keyword(s):  
Molecular Structure ◽  
Phenolic Compounds ◽  
Central America ◽  
Structural Characterization ◽  
Chemical Properties ◽  
The Other ◽  
Chromatographic Techniques ◽  
Ft Ir ◽  
Color Source

ABSTRACTNatural dyes have been extracted from both plants and animal to give color to textiles and handicrafts. This is the case of purple dye extracted from Justicia spicigera Schldt, an acanthaceae used as a color source since pre-Hispanic period in the Mayan area of Mexico and Central America. Spectroscopic (UV-Vis and FT-IR) and chromatographic (PY-GC/MS) techniques were employed in order to characterize some of their chemical properties. UV-VIS absorption spectra indicates a λmaxpeak at 581 nm, value associated to anthocyanins group under bathochromic effect. On the other hand, a structural characterization realized by FT-IR and Py-GC/MS indicated the presence of polar hydroxibenzoic acids and phenolic compounds which are characteristics of the molecular structure of anthocyanins.

Carbon Solvates: Redox Properties and Single Crystal X-Ray Structure

1990 ◽  
Vol 206 ◽  
Author(s):  
S. M. Gorun ◽  
M. A. Greaney ◽  
D. M. Cox ◽  
R. Sherwood ◽  
C. Day ◽  
...  
Keyword(s):  
Single Crystal ◽  
Structural Characterization ◽  
Molecular Level ◽  
Research Effort ◽  
Chemical Properties ◽  
Redox Properties ◽  
X Ray ◽  
The Subject ◽  
Intense Research

Carbon aggregates of various nuclearities have been recently the subject of renewed interest [1]. Despite an intense research, effort no molecular level characterization of C60 and related molecules has been reported yet [1,2]. Moreover, the chemical properties of these materials is virtually unknown. In this paper we report briefly the preparation, electrochemical and structural characterization of crystalline C60/70 solvates [3].

scholarly journals Structural characterization of calcium glycinate, magnesium glycinate and zinc glycinate

2017 ◽  
Vol 10 (03) ◽  
pp. 1650052 ◽  
Author(s):  
Li-Hui Yin ◽  
Xu-Ping Liu ◽  
Lu-Yao Yi ◽  
Jin Wang ◽  
Ya-Jun Zhang ◽  
...  
Keyword(s):  
Structural Characterization ◽  
Metal Ion ◽  
Chemical Properties ◽  
Structure Characterization ◽  
Metal Compounds ◽  
Nutrient Supplements ◽  
Physico Chemical ◽  
Metal Contents ◽  
New Type

Metal glycinate chelates are formed by glycine and metal compounds through chemical reactions. Calcium glycinate, magnesium glycinate and zinc glycinate are kinds of new-type and ideal nutrient supplements, which have satisfactory physico-chemical properties and bioactivities. They are important for prophylaxis and treat metal deficiency. The structural characterization shows that the metal ion is bonded to the amino and carboxyl group to form two five-membered rings. This paper mainly studies the structure characterization of the metal chelated glycinates by their solubility, infrared spectrum, thermal analysis, mass spectrometry, polycrystal diffraction, the metal contents and glycine contents of calcium glycinate, magnesium glycinate and zinc glycinate.

Molecular, chemical, and structural characterization of prostaglandin A2 as a novel agonist for Nur77

2019 ◽  
Vol 476 (19) ◽  
pp. 2757-2767 ◽  
Author(s):  
Sowmya P. Lakshmi ◽  
Aravind T. Reddy ◽  
Asoka Banno ◽  
Raju C. Reddy
Keyword(s):  
Structural Characterization ◽  
Hormone Receptors ◽  
Target Genes ◽  
Unsaturated Fatty Acids ◽  
Biological Effects ◽  
Chemical Properties ◽  
Orphan Receptor ◽  
Dynamic Simulations ◽  
Prostaglandin A2

Abstract Nur77 is a transcription factor belonging to the NR4A subfamily of nuclear hormone receptors. Upon induction, Nur77 modulates the expression of its target genes and controls a variety of biological and pathophysiological processes. Prior research that revealed a structurally atypical ligand-binding domain (LBD) and failed to locate an endogenous ligand had led to a classification of Nur77 as an orphan receptor. However, several more recent studies indicate that small synthetic molecules and unsaturated fatty acids can bind to Nur77. Discovery of additional endogenous ligands will facilitate our understanding of the receptor's functions and regulatory mechanisms. Our data have identified prostaglandin A2 (PGA2), a cyclopentenone prostaglandin (PG), as such a ligand. Cyclopentenone PGs exert their biological effects primarily by forming protein adducts via the characteristic electrophilic β-carbon(s) located in their cyclopentenone rings. Our data show that PGA2 induces Nur77 transcriptional activity by forming a covalent adduct between its endocyclic β-carbon, C9, and Cys566 in the receptor's LBD. The importance of this endocyclic β-carbon was substantiated by the failure of PGs without such electrophilic properties to react with Nur77. Calculated chemical properties and data from reactive molecular dynamic simulations, intrinsic reaction co-ordinate modeling, and covalent molecular docking also corroborate the selectivity of PGA2's C9 β-carbon towards Nur77's Cys. In summary, our molecular, chemical, and structural characterization of the PGA2–Nur77 interaction provides the first evidence that PGA2 is an endogenous Nur77 agonist.

scholarly journals Structural Characterization of Albendazole with the Use of X-Ray Diffraction

2014 ◽  
Vol 70 (a1) ◽  
pp. C1808-C1808 ◽  
Author(s):  
Kelly Lixandrão ◽  
Fabio Ferreira
Keyword(s):  
Crystal Structures ◽  
Structural Characterization ◽  
Rietveld Method ◽  
Low Cost ◽  
Chemical Properties ◽  
X Ray Diffraction ◽  
Scanning Calorimetry ◽  
X Ray ◽  
Physical Chemical

Drugs may present polycrystalline polymorphism (property of a substance to crystallize in more than one form or crystal structure). These variations can cause changes in physical-chemical properties and differences between the polymorphs as shape, solubility, density, melting range, among other consequences, leading to formulations that are not effective, although the chemical formula is the same [1]. Drugs such as albendazole (C12H15N3O2S, which is one of the most effective anthelmintics, [2] showing activity against nematodes, trematodes and cestodes, reasons that added to its safety and low cost have made it a drug widely used in human medicine and veterinary), has more than two different crystal structures, and only two of them are known. The X-ray powder diffraction is a powerful technique used in the structural characterization of drugs, and coupled with the Rietveld method [4], the quantification of the active phases, through the knowledge of their crystal structures, becomes possible. In this paper we discuss results on the differences between the polymorphs of albendazole, with data obtained by means of X-ray diffraction, thermal analysis (differential scanning calorimetry and thermogravimetric analysis), Fourier transform infrared spectroscopy and scanning electron microscopy.

scholarly journals Novel Formulation Based on Chitosan-Arabic Gum Nanoparticles Entrapping Propolis Extract Production, physico-chemical and structural characterization

2019 ◽  
Vol 69 (12) ◽  
pp. 3756-3760 ◽  
Author(s):  
Simona Cavalu ◽  
Simona Bisboaca ◽  
Ileana Mariana Mates ◽  
Paula Melania Pasca ◽  
Vasile Laslo ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Structural Characterization ◽  
Chemical Properties ◽  
Arabic Gum ◽  
Propolis Extract ◽  
Physico Chemical ◽  
Processing And Storage ◽  
And Storage ◽  
Novel Design

The aim of our study was to prepare and characterize chitosan-based nanoparticles encapsulating propolis extract by ionotropic gelation and glutaraldehyde cross-linking technique. Both spectroscopic (UV-Vis, FTIR) and microscopic techniques (AFM) were applied for structural characterization of nanoparticles, along with entrapment and release study of propolis extract. The physico-chemical properties and morphological features of the obtained nanoparticles demonstrated a good correlation between all the investigated methods. Moreover, the bioactive compounds were stable upon the encapsulation procedure. Propolis release from the polymeric matrix was monitored in both simulated gastric acid and simulated intestinal fluids, concluding that our proposed formulation is suitable for controlled release. These results may provide a novel design, with improved bioavailability, stability and nutritional value of propolis bioactive compounds during processing and storage, with possible applications in food and nutraceutical industries.

New ultrastructural findings about Borrelia burgdorferi by cryofixation, negative staining, thin sectioning and scanning techniques

1990 ◽  
Vol 48 (3) ◽  
pp. 582-583
Author(s):  
S. F. Hayes ◽  
M. D. Corwin ◽  
T. G. Schwan ◽  
D. W. Dorward ◽  
W. Burgdorfer
Keyword(s):  
Lyme Disease ◽  
Borrelia Burgdorferi ◽  
Structural Characterization ◽  
Negative Staining ◽  
Low Speed ◽  
Thin Sectioning ◽  
Ultrastructural Findings

Characterization of Borrelia burgdorferi strains by means of negative staining EM has become an integral part of many studies related to the biology of the Lyme disease organism. However, relying solely upon negative staining to compare new isolates with prototype B31 or other borreliae is often unsatisfactory. To obtain more satisfactory results, we have relied upon a correlative approach encompassing a variety EM techniques, i.e., scanning for topographical features and cryotomy, negative staining and thin sectioning to provide a more complete structural characterization of B. burgdorferi.For characterization, isolates of B. burgdorferi were cultured in BSK II media from which they were removed by low speed centrifugation. The sedimented borrelia were carefully resuspended in stabilizing buffer so as to preserve their features for scanning and negative staining. Alternatively, others were prepared for conventional thin sectioning and for cryotomy using modified procedures. For thin sectioning, the fixative described by Ito, et al.

Structural characterization of the PPIase domain of FKBP51, a cochaperone of human Hsp90

2011 ◽  
Vol 44 (06) ◽  
Author(s):  
A Bracher ◽  
C Kozany ◽  
AK Thost ◽  
F Hausch
Keyword(s):  
Structural Characterization ◽  
Ppiase Domain
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