Chemistry of organosilicon compounds. 167. 3,4,7,8-Tetrasilacycloocta-1,5-diyne, 3,6,7-trisilacyclohepta-1,4-diyne and related compounds. New class of cyclic compounds composed of polysilanes and acetylenes

1983 ◽  
Vol 105 (10) ◽  
pp. 3359-3360 ◽  
Author(s):  
Hideki Sakurai ◽  
Yasuhiro Nakadaira ◽  
Akira Hosomi ◽  
Yuichi Eriyama ◽  
Chizuko Kabuto
Keyword(s):  
Organosilicon Compounds ◽  
New Class ◽  
Cyclic Compounds ◽  
Related Compounds

Synthesis of trans-2-[N-(2-Hydroxy-1,2,3,4-tetrahydronaphthalene-1-yl)]iminothiazolidine and Related Compounds - A New Class of Antidepressants

1992 ◽  
Vol 57 (2) ◽  
pp. 415-424 ◽  
Author(s):  
Upendra K. Shukla ◽  
Raieshwar Singh ◽  
J. M. Khanna ◽  
Anil K. Saxena ◽  
Hemant K. Singh ◽  
...  
Keyword(s):  
Antidepressant Activity ◽  
Antiparasitic Activity ◽  
New Class ◽  
Related Compounds ◽  
Better Than

Antiparasitic and antidepressant activities exhibited by tetramisole (I) and its enantiomers prompted the study of its structural analogs trans-2-[N-(2-hydroxy-1,2,3,4-tetrahydronaphthalene/indane-1-yl)]iminothiazolidine (VIII/IX) and 2,3,4a,5,6,10b-hexahydronaphtho[1',2':4,5]-imidazo[2,1-b]thiazole (XII), 2,3,4a,5-tetrahydro-9bH-indeno[1',2':4,5]imidazo[2,1-b]thiazole (XIII), and 2,3,4a,5-tetrahydro-9bH-indeno[1',2':4,5]imidazo[2,1-b]thiazole (XVI), and a homolog 3,4,6,7-tetrahydro-7-phenyl-2H-imidazo[2,1-b]-1,3-thiazine (XX). While none of these compounds showed any noteworthy antiparasitic activity, the trans-2-[N-(2-hydroxy-1,2,3,4-tetrahydronaphthalene-1-yl)]iminothiazolidine (VIII) has shown marked antidepressant activity, better than imipramine in the tests used, and provides a new structural lead for antidepressants.

Tetrabromocinnamic Acid (TBCA) and Related Compounds Represent a New Class of Specific Protein Kinase CK2 Inhibitors

ChemBioChem ◽  
2007 ◽  
Vol 8 (1) ◽  
pp. 129-139 ◽  
Author(s):  
Mario A. Pagano ◽  
Giorgia Poletto ◽  
Giovanni Di Maira ◽  
Giorgio Cozza ◽  
Maria Ruzzene ◽  
...  
Keyword(s):  
Protein Kinase ◽  
Protein Kinase Ck2 ◽  
Specific Protein ◽  
New Class ◽  
Kinase Ck2 ◽  
Related Compounds ◽  
Ck2 Inhibitors ◽  
Specific Protein Kinase

ChemInform Abstract: Improved Transparency-Efficiency Trade-Off in a New Class of Nonlinear Organosilicon Compounds.

ChemInform ◽  
2010 ◽  
Vol 23 (5) ◽  
pp. no-no
Author(s):  
G. MIGNANI ◽  
M. BARZOUKAS ◽  
J. ZYSS ◽  
G. SOULA ◽  
F. BALEGROUNE ◽  
...  
Keyword(s):  
Organosilicon Compounds ◽  
Trade Off ◽  
New Class
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