Isotopically sensitive branching and its effect on the observed intramolecular isotope effects in cytochrome P-450 catalyzed reactions: a new method for the estimation of intrinsic isotope effects

Jeffrey P. Jones; Kenneth R. Korzekwa; Allan E. Rettie; William F. Trager

doi:10.1021/ja00282a037

Isotopically sensitive branching and its effect on the observed intramolecular isotope effects in cytochrome P-450 catalyzed reactions: a new method for the estimation of intrinsic isotope effects

Journal of the American Chemical Society ◽

10.1021/ja00282a037 ◽

1986 ◽

Vol 108 (22) ◽

pp. 7074-7078 ◽

Cited By ~ 80

Author(s):

Jeffrey P. Jones ◽

Kenneth R. Korzekwa ◽

Allan E. Rettie ◽

William F. Trager

Keyword(s):

Isotope Effects ◽

New Method ◽

Catalyzed Reactions ◽

Cytochrome P 450

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Correction. Isotopically Sensitive Branching and Its Effect on the Observed Intramolecular Isotope Effects in Cytochrome P-450 Catalyzed Reactions: A New Method for the Estimation of Intrinsic Isotope Effects

Journal of the American Chemical Society ◽

10.1021/ja00214a601 ◽

1988 ◽

Vol 110 (6) ◽

pp. 2018-2018 ◽

Cited By ~ 1

Author(s):

Jeffrey P. Jones ◽

Kenneth R. Korzekwa ◽

Allan E. Rettie ◽

William F. Trager

Keyword(s):

Isotope Effects ◽

New Method ◽

Catalyzed Reactions ◽

Cytochrome P 450

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ChemInform Abstract: Isotopically Sensitive Branching and Its Effect on the Observed Intramolecular Isotope Effects in Cytochrome P-450 Catalyzed Reactions: A New Method for the Estimation of Intrinsic Isotope Effects.

ChemInform ◽

10.1002/chin.198712138 ◽

1987 ◽

Vol 18 (12) ◽

Author(s):

J. P. JONES ◽

K. R. KORZEKWA ◽

A. E. RETTIE ◽

W. F. TRAGER

Keyword(s):

Isotope Effects ◽

New Method ◽

Catalyzed Reactions ◽

Cytochrome P 450

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Deuterium isotope effects on toluene metabolism. Product release as a rate-limiting step in cytochrome P-450 catalysis

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(89)92511-4 ◽

1989 ◽

Vol 160 (2) ◽

pp. 844-849 ◽

Cited By ~ 34

Author(s):

Kah-Hiing John Ling ◽

Robert P. Hanzlik

Keyword(s):

Isotope Effects ◽

Product Release ◽

Rate Limiting Step ◽

Limiting Step ◽

Deuterium Isotope Effects ◽

Rate Limiting ◽

Cytochrome P 450

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Tracer Studies of Acid-Catalyzed Reactions. VI. Deuterium Redistribution and Isotope Effects inn-Butene Isomerization over Alumina and Silica-Alumina Catalysts

Journal of the American Chemical Society ◽

10.1021/ja00980a008 ◽

1967 ◽

Vol 89 (4) ◽

pp. 778-787 ◽

Cited By ~ 35

Author(s):

Joe W. Hightower ◽

W. Keith. Hall

Keyword(s):

Isotope Effects ◽

Tracer Studies ◽

Silica Alumina ◽

Acid Catalyzed ◽

Catalyzed Reactions ◽

Butene Isomerization ◽

Alumina Catalysts

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New method of evaluation of the kinetic parameters of bi-exponential enzyme-catalyzed reactions

The International Journal of Biochemistry & Cell Biology ◽

10.1016/s1357-2725(98)00025-9 ◽

1998 ◽

Vol 30 (6) ◽

pp. 735-743 ◽

Cited By ~ 3

Author(s):

Carmelo Garrido-del Solo ◽

Francisco Garcı́a-Cánovas ◽

José Tudela ◽

Bent H. Havsteen ◽

Ramón Varón-Castellanos

Keyword(s):

Kinetic Parameters ◽

New Method ◽

Catalyzed Reactions ◽

Enzyme Catalyzed Reactions ◽

Method Of Evaluation

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Kinetic Isotope Effects in Cytochrome P-450-Catalyzed Oxidation Reactions. II. Interactions of Cytochrome P-450 with Substrates and Nadph-Cytochrome % MathType!MTEF!2!1!+-% feaagCart1ev2aaatCvAUfeBSjuyZL2yd9gzLbvyNv2CaerbuLwBLn% hiov2DGi1BTfMBaeXatLxBI9gBaerbd9wDYLwzYbItLDharqqtubsr% 4rNCHbGeaGqiVu0Je9sqqrpepC0xbbL8F4rqqrFfpeea0xe9Lq-Jc9% vqaqpepm0xbba9pwe9Q8fs0-yqaqpepae9pg0FirpepeKkFr0xfr-x% fr-xb9adbaqaaeGaciGaaiaabeqaamaabaabaaGcbaGabm4yayaaDa% aaaa!3700! $$\underset{\raise0.3em\hbox{$\smash{\scriptscriptstyle-}$}}{c} $$ Reductase

Alcohol and Aldehyde Metabolizing Systems-IV ◽

10.1007/978-1-4757-1419-7_11 ◽

1980 ◽

pp. 95-108 ◽

Cited By ~ 1

Author(s):

Anthony Y. H. Lu ◽

Gerald T. Miwa ◽

Susan B. West ◽

Barbara J. Hodshon ◽

William A. Garland

Keyword(s):

Isotope Effects ◽

Kinetic Isotope Effects ◽

Oxidation Reactions ◽

Nadph Cytochrome ◽

Kinetic Isotope ◽

Cytochrome P 450 ◽

Catalyzed Oxidation

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Kinetic isotope effects and their application in the mechanistic studies of some transition-metal-catalyzed reactions

Scientia Sinica Chimica ◽

10.1360/n032015-00254 ◽

2016 ◽

Vol 46 (6) ◽

pp. 573-578 ◽

Cited By ~ 1

Author(s):

Yujing Zhou ◽

Jian-Bo Wang

Keyword(s):

Transition Metal ◽

Isotope Effects ◽

Kinetic Isotope Effects ◽

Mechanistic Studies ◽

Kinetic Isotope ◽

Transition Metal Catalyzed ◽

Catalyzed Reactions ◽

Metal Catalyzed

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Two Distinct Electrophilic Oxidants Effect Hydroxyl- ation in Cytochrome P-450-Catalyzed Reactions

Journal of the American Chemical Society ◽

10.1021/ja981990f ◽

1998 ◽

Vol 120 (37) ◽

pp. 9718-9719 ◽

Cited By ~ 65

Author(s):

Patrick H. Toy ◽

Martin Newcomb ◽

Minor J. Coon ◽

Alfin D. N. Vaz

Keyword(s):

Catalyzed Reactions ◽

Cytochrome P 450

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Combination of enzyme- and Lewis acid-catalyzed reactions: a new method for the synthesis of 6,7-dihydrobenzofuran-4(5H)-ones starting from 2,5-dimethylfuran and 1,3-cyclohexanediones

Organic & Biomolecular Chemistry ◽

10.1039/c3ob40926k ◽

2013 ◽

Vol 11 (34) ◽

pp. 5692 ◽

Cited By ~ 5

Author(s):

Chimène Asta ◽

Dietmar Schmidt ◽

Jürgen Conrad ◽

Wolfgang Frey ◽

Uwe Beifuss

Keyword(s):

Lewis Acid ◽

New Method ◽

Acid Catalyzed ◽

Catalyzed Reactions

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Intramolecular isotope effects associated with meta-hydroxylation of biphenyl catalyzed by cytochrome P-450

Biochemical and Biophysical Research Communications ◽

10.1016/0006-291x(84)91475-x ◽

1984 ◽

Vol 118 (3) ◽

pp. 867-872 ◽

Cited By ~ 6

Author(s):

D.C. Swinney ◽

W.N. Howald ◽

W.F. Trager

Keyword(s):

Isotope Effects ◽

Cytochrome P 450

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