Stereochemistry of the cross-coupling reaction of chiral alkylsilanes with aryl triflates: a novel approach to optically active compounds

1990 ◽  
Vol 112 (21) ◽  
pp. 7793-7794 ◽  
Author(s):  
Yasuo Hatanaka ◽  
Tamejiro Hiyama
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Optically Active ◽  
Active Compounds ◽  
Novel Approach ◽  
Cross Coupling Reaction ◽  
The Cross

An Efficient Synthesis of Optically Active 4-Benzyloxy-3-hydoroxy-1-butyne and Its Cross-Coupling Reaction

Heterocycles ◽  
1992 ◽  
Vol 33 (2) ◽  
pp. 831 ◽  
Author(s):  
Seiichi Takano ◽  
Masashi Akiyama ◽  
Takumichi Sugihara ◽  
Kunio Ogasawara
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Optically Active ◽  
Efficient Synthesis ◽  
Cross Coupling Reaction

Pd-catalyzed desulfitative arylation of olefins by N-methoxysulfonamide

2022 ◽  
Author(s):  
Subhadra Ojha ◽  
Niranjan Panda
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Type Reaction ◽  
Cross Coupling Reaction ◽  
The Cross

A novel Pd-catalyzed protocol desulfitative Heck type reaction of N-methoxy aryl sulfonamides with alkenes was reported. The cross-coupling reaction was performed successfully with a variety of olefins to obtainaryl alkenes....

scholarly journals A DFT Study on FeI/FeII/FeIII Mechanism of the Cross-Coupling between Haloalkane and Aryl Grignard Reagent Catalyzed by Iron-SciOPP Complexes

Molecules ◽  
2020 ◽  
Vol 25 (16) ◽  
pp. 3612 ◽  
Author(s):  
Akhilesh Sharma ◽  
Masaharu Nakamura
Keyword(s):  
Density Functional ◽  
Molecular Mechanic ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Dft Study ◽  
Reaction Pathways ◽  
Hydrogen Elimination ◽  
Cross Coupling Reaction ◽  
The Cross ◽  
A Chain

To explore plausible reaction pathways of the cross-coupling reaction between a haloalkane and an aryl metal reagent catalyzed by an iron–phosphine complex, we examine the reaction of FeBrPh(SciOPP) 1 and bromocycloheptane employing density functional theory (DFT) calculations. Besides the cross-coupling, we also examined the competitive pathways of β-hydrogen elimination to give the corresponding alkene byproduct. The DFT study on the reaction pathways explains the cross-coupling selectivity over the elimination in terms of FeI/FeII/FeIII mechanism which involves the generation of alkyl radical intermediates and their propagation in a chain reaction manner. The present study gives insight into the detailed molecular mechanic of the cross-coupling reaction and revises the FeII/FeII mechanisms previously proposed by us and others.

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