Kinetics of a 1,3-CH carbene insertion reaction: tert-butylchlorocarbene

1990 ◽  
Vol 112 (14) ◽  
pp. 5642-5644 ◽  
Author(s):  
Robert A. Moss ◽  
Guo Jie Ho
Keyword(s):  
Insertion Reaction ◽  
Carbene Insertion ◽  
Kinetics Of

scholarly journals Organocatalytic Asymmetric Synthesis of α-Amino Esters from Sulfoxonium Ylides

2021 ◽  
Author(s):  
Wengang Guo ◽  
Hai Huang ◽  
Jianwei Sun
Keyword(s):  
Asymmetric Synthesis ◽  
Insertion Reaction ◽  
Metal Catalyst ◽  
Insertion Reactions ◽  
Amino Esters ◽  
Carbene Insertion

Described here is the first organocatalytic asymmetric N−H insertion reaction of α-carbonyl sulfoxonium ylides. Without a metal catalyst, this reaction represents an attractive complement to the well-established carbene insertion reactions....

A stereocontrolled, enantiomerically specific total synthesis of thienamycin

1980 ◽  
Vol 289 (1036) ◽  
pp. 191-195 ◽  
Keyword(s):  
Total Synthesis ◽  
Aspartic Acid ◽  
Ring System ◽  
Insertion Reaction ◽  
Carbene Insertion ◽  
Metal Catalyzed

A versatile stereocontrolled total synthesis of thienamycin starting from L-aspartic acid is reported. Stereocontrol is achieved by potassium tri- sec -butylborohydride reduction of a thermodynamically formed 3α-acetylazetidinone intermediate. The key [3.2.0] bicyclic ring system is prepared by a metal catalyzed carbene insertion reaction.

scholarly journals A NOVEL, CYCLOBUTANONE-FORMING CARBENE INSERTION REACTION. TETRACYCLO[7.3.1.02,5.05,10]TRIDECAN-4-ONE FROM 1-(TRICYCLO[5.3.1.03,8]UNDEC-3-YL)-2-DIAZOETHAN-1-ONE

1975 ◽  
Vol 4 (9) ◽  
pp. 957-960 ◽  
Author(s):  
Naotake Takaishi ◽  
Yoshiaki Fujikura ◽  
Yoshiaki Inamoto ◽  
Hiroshi Ikeda
Keyword(s):  
Insertion Reaction ◽  
Carbene Insertion

The Kinetics of the Insertion Reaction of Tin(II) Chloride with a Mono-substituted Derivative of Cyclopentadienyliron Dicarbonyl Dimer

1972 ◽  
Vol 50 (7) ◽  
pp. 972-976 ◽  
Author(s):  
P. F. Barrett ◽  
W. J. Jacobs
Keyword(s):  
Activation Enthalpy ◽  
Visible Spectrum ◽  
Insertion Reaction ◽  
Triphenyl Phosphite ◽  
Two Stage ◽  
Temperature Range ◽  
Metal Metal ◽  
Iron Iron ◽  
Kinetics Of

The kinetics of the thermal insertion reaction of SnCl2 with the metal–metal bonded complex (π-C5H5)2Fe2(CO)3P(OC6H5)3 have been studied by following the change in the visible spectrum in THF over the temperature range 40.0 to 55.0 °C. The data are consistent with a two-stage mechanism involving the formation of an intermediate in which the iron–iron bond has been broken but the carbonyl bridges are left intact. From the activation enthalpy of 23.4 ± 0.5 kcal/mol for the formation of the intermediate it is concluded that the triphenyl phosphite has brought about a weakening of the iron–iron bond.

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