scholarly journals Organocatalytic Asymmetric Synthesis of α-Amino Esters from Sulfoxonium Ylides

2021 ◽  
Author(s):  
Wengang Guo ◽  
Hai Huang ◽  
Jianwei Sun
Keyword(s):  
Asymmetric Synthesis ◽  
Insertion Reaction ◽  
Metal Catalyst ◽  
Insertion Reactions ◽  
Amino Esters ◽  
Carbene Insertion

Described here is the first organocatalytic asymmetric N−H insertion reaction of α-carbonyl sulfoxonium ylides. Without a metal catalyst, this reaction represents an attractive complement to the well-established carbene insertion reactions....

scholarly journals Uncommon carbene insertion reactions

2021 ◽  
Author(s):  
Ming-Yao Huang ◽  
Shou-Fei Zhu
Keyword(s):  
Transition Metal ◽  
Insertion Reaction ◽  
Insertion Reactions ◽  
Carbene Insertion

Transition-metal-catalysed carbene insertion reaction is a straightforward and efficient protocol for the construction of carbon-carbon or carbon-heteroatom bonds. Compared to the intensively studied and well-established “common” carbene insertion reactions, including...

Engineering of RuMb: Toward a Green Catalyst for Carbene Insertion Reactions

2017 ◽  
Vol 56 (10) ◽  
pp. 5623-5635 ◽  
Author(s):  
Matthew W. Wolf ◽  
David A. Vargas ◽  
Nicolai Lehnert
Keyword(s):  
Insertion Reactions ◽  
Green Catalyst ◽  
Carbene Insertion

scholarly journals Enantioselective synthesis of α-alkenyl α-amino acids via N–H insertion reactions

2016 ◽  
Vol 7 (2) ◽  
pp. 1104-1108 ◽  
Author(s):  
Jun-Xia Guo ◽  
Ting Zhou ◽  
Bin Xu ◽  
Shou-Fei Zhu ◽  
Qi-Lin Zhou
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Enantioselective Synthesis ◽  
Insertion Reaction ◽  
Amino Acid Derivatives ◽  
Insertion Reactions ◽  
Phosphoric Acids

A new highly enantioselective route to α-alkenyl α-amino acid derivatives using a N–H insertion reaction of vinyldiazoacetates and tert-butyl carbamate cooperatively catalyzed by achiral dirhodium(ii) carboxylates and chiral spiro phosphoric acids was developed.

ChemInform Abstract: Tandem Michael-Carbene Insertion Reactions of Alkynyliodonium Salts. Extremely Efficient Cyclopentene Annulations.

ChemInform ◽  
1987 ◽  
Vol 18 (20) ◽  
Author(s):  
M. OCHIAI ◽  
M. KUNISHIMA ◽  
Y. NAGAO ◽  
K. FUJI ◽  
M. SHIRO ◽  
...  
Keyword(s):  
Insertion Reactions ◽  
Carbene Insertion

A stereocontrolled, enantiomerically specific total synthesis of thienamycin

1980 ◽  
Vol 289 (1036) ◽  
pp. 191-195 ◽  
Keyword(s):  
Total Synthesis ◽  
Aspartic Acid ◽  
Ring System ◽  
Insertion Reaction ◽  
Carbene Insertion ◽  
Metal Catalyzed

A versatile stereocontrolled total synthesis of thienamycin starting from L-aspartic acid is reported. Stereocontrol is achieved by potassium tri- sec -butylborohydride reduction of a thermodynamically formed 3α-acetylazetidinone intermediate. The key [3.2.0] bicyclic ring system is prepared by a metal catalyzed carbene insertion reaction.

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