Concentrated Salt Solutions. II. Viscosity and Density of Sodium Thiocyanate, Sodium Perchlorate and Sodium Iodide.

1956 ◽  
Vol 60 (2) ◽  
pp. 186-189 ◽  
Author(s):  
M. L. Miller ◽  
M. Doran
Keyword(s):  
Sodium Iodide ◽  
Sodium Perchlorate ◽  
Sodium Thiocyanate ◽  
Salt Solutions

Effect of sodium thiocyanate and sodium perchlorate on poly(N-isopropylacrylamide) collapse

2020 ◽  
Vol 22 (1) ◽  
pp. 189-195
Author(s):  
Andrea Pica ◽  
Giuseppe Graziano
Keyword(s):  
Sodium Perchlorate ◽  
Sodium Thiocyanate ◽  
Conformational States

The two conformational states of PNIPAM have a similar accessibility to perchlorate ions.

Sodium-Iodide Symporter Mediates Iodide Secretion in Rat Gastric Mucosa In Vitro

2006 ◽  
Vol 231 (3) ◽  
pp. 277-281 ◽  
Author(s):  
Malin Josefsson ◽  
Lena Evilevitch ◽  
Björn Weström ◽  
Torsten Grunditz ◽  
Eva Ekblad
Keyword(s):  
Gastric Mucosa ◽  
Sodium Iodide ◽  
Sodium Perchlorate ◽  
Nitric Oxide Donor ◽  
Sodium Iodide Symporter ◽  
Iodide Transport ◽  
Gastric Lumen ◽  
Rat Gastric Mucosa ◽  
Mucosal Side

In vivo studies on rats have demonstrated that considerable amounts of iodide are transported from the bloodstream into the gastric lumen. The mechanisms for and functional significance of this transport are poorly understood. Active (driven by Na+/K+-ATPase) iodide transport into thyroid follicular cells is mediated by the sodium-iodide symporter (NIS), which is also abundantly expressed in gastric mucosa. We aimed to further investigate the iodide transport in gastric mucosa and the Possible role of NIS in this transport process. Iodide transport in rat gastric mucosa was studied in vitro in an Ussing chamber system using 125I as a marker. The system allows measurements in both directions over a mucosal specimen. A considerable transport of iodide (from the serosal to the mucosal side) was established across the gastric mucosa, whereas in the opposite direction (mucosa to serosa), iodide transport was negligible. Sodium Perchlorate (NaClO4), a competitive inhibitor of NIS, and ouabain, an inhibitor of the Na+/K+-ATPase, both attenuated gastric iodide transport from the serosal to the mucosal side. To investigate a possible neuroendocrine regulation of the iodide transport identified to occur from the serosal to the mucosal side of the stomach, thyroid-stimulating hormone (TSH), thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide (VIP), histamine, or nitric oxide donor S-nitroso-N-acetyl-D,L-penicillamine (SNAP) was added. None of these substances influenced the iodide transport. We conclude that iodide is actively transported into the gastric lumen and that this transport is at least partly mediated by NIS. Additional investigations are needed to understand the regulation and significance of this transport.

scholarly journals The cerebral sodium-plus-potassium ion-stimulated adenosine triphosphatase of bovine brain and its microsomal matrix

1970 ◽  
Vol 119 (3) ◽  
pp. 367-376 ◽  
Author(s):  
I. Pull ◽  
H. McIlwain
Keyword(s):  
Amino Acids ◽  
Density Gradient ◽  
Adenosine Triphosphatase ◽  
Sodium Iodide ◽  
Density Gradient Centrifugation ◽  
Gradient Centrifugation ◽  
Sodium Thiocyanate ◽  
Adenosine Triphosphatase Activity ◽  
Ionic Detergent ◽  
High Concentrations

1. Adenosine triphosphatase activities of dispersions prepared from bovine cerebral cortex that had been frozen, were greater than those of dispersions prepared from fresh tissue. The subcellular distribution of components of the dispersion was not altered by freezing the tissue and a microsomal fraction enriched in Na++K+-stimulated adenosine triphosphatase activity was prepared. 2. The bovine cerebral microsomes were further treated with a 2m-sodium iodide reagent to obtain a particulate preparation with minimal Na++K+-independent adenosine triphosphatase activity. Na++K+-stimulated activity was increased by the sodium iodide treatment and this preparation was shown to be enriched in lipid constituents. 3. Density-gradient centrifugation of the sodium iodide treated preparation gave three main subfractions each containing approximately equal amounts of phospholipid and protein. Further exposure of the sodium iodide-treated preparation to the 2m-sodium iodide reagent altered the distribution of protein and phospholipid among the fractions obtained by density-gradient centrifugation. Dissociation of phospholipids from protein in the sodium iodide-treated preparation was brought about also by high concentrations of arginine. Concentrated solutions of arginine and sodium thiocyanate brought about dissociation of phospholipids from protein of the microsomal preparation. 4. Many amino acids were found to inhibit Na++K+-stimulated adenosine triphosphatase activity when present in high concentrations. The inhibition was complex but resulted, in part at least, from diminished affinity for ATP and Na+ in the presence of the amino acids. 5. A non-ionic detergent, Lubrol W, solubilized up to 40% of the enzyme activity of the sodium iodide-treated preparation together with 30% of the protein and phospholipid in the preparation. Protein was released from the sodium iodide-treated preparation by pancreatic elastase but Na++K+-stimulated adenosine triphosphatase activity of the residue was diminished. Ultrasonic treatment of the sodium iodide-treated preparation failed to release a significant proportion of Na++K+-stimulated adenosine triphosphatase activity into a form not deposited by ultracentrifugation.

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