Characterization of Platinum Anticancer Drug Protein-Binding Sites Using a Top-Down Mass Spectrometric Approach

2008 ◽  
Vol 47 (1) ◽  
pp. 17-19 ◽  
Author(s):  
Christian G. Hartinger ◽  
Yury O. Tsybin ◽  
Jens Fuchser ◽  
Paul J. Dyson
Keyword(s):  
Protein Binding ◽  
Anticancer Drug ◽  
Binding Sites ◽  
Mass Spectrometric ◽  
Top Down ◽  
Protein Binding Sites ◽  
Mass Spectrometric Approach ◽  
Drug Protein Binding

scholarly journals Fragmentation methods on the balance: unambiguous top–down mass spectrometric characterization of oxaliplatin–ubiquitin binding sites

2011 ◽  
Vol 402 (8) ◽  
pp. 2655-2662 ◽  
Author(s):  
Samuel M. Meier ◽  
Yury O. Tsybin ◽  
Paul J. Dyson ◽  
Bernhard K. Keppler ◽  
Christian G. Hartinger
Keyword(s):  
Binding Sites ◽  
Mass Spectrometric ◽  
Top Down ◽  
Ubiquitin Binding

Activation of Platinum(IV) Prodrugs by Cytochrome c and Characterization of the Protein Binding Sites

2016 ◽  
Vol 13 (9) ◽  
pp. 3216-3223 ◽  
Author(s):  
Alessia Lasorsa ◽  
Olga Stuchlíková ◽  
Viktor Brabec ◽  
Giovanni Natile ◽  
Fabio Arnesano
Keyword(s):  
Cytochrome C ◽  
Protein Binding ◽  
Binding Sites ◽  
Protein Binding Sites

Combined Top-Down and Bottom-Up Mass Spectrometric Approach to Characterization of Biomarkers for Renal Disease

2005 ◽  
Vol 77 (22) ◽  
pp. 7163-7171 ◽  
Author(s):  
Michael J. Chalmers ◽  
Colin Logan Mackay ◽  
Christopher L. Hendrickson ◽  
Stefan Wittke ◽  
Michael Walden ◽  
...  
Keyword(s):  
Renal Disease ◽  
Mass Spectrometric ◽  
Top Down ◽  
Bottom Up ◽  
Mass Spectrometric Approach

Top-Down Mass Spectrometric Approach for the Full Characterization of Insulin−Cisplatin Adducts

2009 ◽  
Vol 81 (9) ◽  
pp. 3507-3516 ◽  
Author(s):  
Estefanía Moreno-Gordaliza ◽  
Benito Cañas ◽  
María A. Palacios ◽  
M. Milagros Gómez-Gómez
Keyword(s):  
Mass Spectrometric ◽  
Top Down ◽  
Full Characterization ◽  
Mass Spectrometric Approach
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