scholarly journals Role of the Phosphine Ligands on the Stabilization of Monoadducts of the Model Nucleobases 1-Methylcytosine and 9-Methylguanine in Platinum(II) Complexes

2008 ◽  
Vol 47 (7) ◽  
pp. 2688-2695 ◽  
Author(s):  
Diego Montagner ◽  
Ennio Zangrando ◽  
Bruno Longato
Keyword(s):  
Phosphine Ligands

Keep it tight: a crucial role of bridging phosphine ligands in the design and optical properties of multinuclear coinage metal complexes

2021 ◽  
Author(s):  
Aleksandra V. Paderina ◽  
Igor O Koshevoy ◽  
Elena V. Grachova
Keyword(s):  
Optical Properties ◽  
Metal Complexes ◽  
Crucial Role ◽  
Phosphine Ligands ◽  
Bridging Ligands ◽  
Coinage Metal ◽  
Metal Interactions ◽  
Metal Metal ◽  
State 1

The copper subgroup metal ions in the oxidation state +1 are classical candidates for the aggregation via non-covalent metal–metal interactions, which are supported by a number of the bridging ligands....

Solvent-free Substitution Reactions of Solid Phosphines with (η5-RC5H4)Fe(CO)2I (R = H, Me) Complexes

2007 ◽  
Vol 62 (3) ◽  
pp. 453-459 ◽  
Author(s):  
Apollinaire Munyaneza ◽  
Muhammad D. Bala ◽  
Neil J. Coville
Keyword(s):  
Benzene Solution ◽  
Phosphine Ligands ◽  
Solvent Free ◽  
Substitution Reactions ◽  
Ionic Complex ◽  
Solvent Free Conditions ◽  
Mechanism Of The Reaction ◽  
Solvent Free Reaction ◽  
Melt Phase

Reactions of (η5-RC5H4)Fe(CO)2I (R = H, Me) complexes with phosphine ligands PR′3 (R′ = Ph, m-Tol, p-C6H4OMe, p-C6H4Cl, p-C6H4F) have been performed under solvent-free conditions in the melt phase and generally yielded the ionic products [(η5-RC5H4)Fe(CO)2PR′3]I rather than the CO substituted products (η5-RC5H4)Fe(CO)(PR′3)I. The complexes have been characterised by IR, NMR and MS techniques. By contrast, the same reactions studied in benzene solution have yielded mainly the CO substitution products. Factors that affect the solvent-free reaction include variation in R and R′ , reaction temperature and the addition of [CpFe(CO)2]2 as a catalyst. The mechanism of the reaction for the formation of the ionic complex is proposed to go via a 19 electron intermediate. This is in contrast to the reaction in bezene that occurs via a 17 electron intermediate, clearly indicating the role of the melt phase in the reaction.

The role of phosphine ligands in the catalytic systems of the Heck reaction with aromatic carboxylic anhydrides

2019 ◽  
Vol 68 (4) ◽  
pp. 817-824
Author(s):  
N. A. Lagoda ◽  
E. V. Larina ◽  
E. V. Yarosh ◽  
A. A. Kurokhtina ◽  
A. F. Schmidt
Keyword(s):  
Heck Reaction ◽  
Phosphine Ligands ◽  
Catalytic Systems

scholarly journals Redox Chemistry and [Au(CN)2-] in the Formation of Gold Metabolites

1994 ◽  
Vol 1 (5-6) ◽  
pp. 351-362 ◽  
Author(s):  
G. Frank Shaw III ◽  
Sabine Schraa ◽  
Ernst Gleichmann ◽  
Yash Paul Grover ◽  
Lothar Dunemann ◽  
...  
Keyword(s):  
Ligand Exchange ◽  
Strong Association ◽  
Enzymatic Reaction ◽  
Phosphine Ligands ◽  
Initial Oxidation ◽  
Full Extent ◽  
Gold Thioglucose ◽  
Pharmacological Significance ◽  
Rate Of Reaction

The role of hypochlorite ion, which can be generated by the enzyme myleoperoxidase, in the biochemistry of gold(I) anti-arthritic drugs was investigated. Sodium hypochlorite (OCl−) directly and rapidly oxidizes AuSTm, Au(CN)2-, AuSTg (gold thioglucose) and auranofin (Et3PAuSATg). The resulting gold(III) species were detected by an Ion Chromotography Ion-Pairing technique that was developed to distinguish gold(I) and gold(III). Formation of Au(III) was also demonstrated spectrophotometrically after the conversion to AuCl4−. The reactions of AuSTm, AuSTg, and auranofin are complex and gold(III) appears only after the initial oxidation of the thiolate (and phosphine) ligands.The enzymatic reaction, using MPO with H2O2 and Cl− as substrates, leads to slow oxidation of Au(CN)2-, AuSTm or AuSTg. The extent and rate of reaction depend on the concentrations of MPO, H2O2, and Au(I). The continued presence of Au(I) during the initial stages of reaction (oxidation of the thiolates in AuSTm and AuSTg) and the conversion to Au(III) in the latter stages of the reaction were demonstrated.Au(CN)2-, a gold metabolite, binds tightly to serum albumin. Unlike other gold(I) complexes, aurocyanide reacts almost negligibly at Cys-34 via ligand exchange. Instead, there is a strong association (K1 = 5.5 × 104 and K2 = 7.0 × 103; n1 = 0.8 and n2 = 3) of intact Au(CN)2-. The full extent of binding is revealed only by equilibrium methods such as NMR or ultrafiltration; the bound gold dissociates extensively on conventional gel-exclusion columns and partially on Penefesky spun columns.The immunological and pharmacological significance of these results are discussed.

Role of dactinomycin in the improved survival of children with Wilms' tumor

JAMA ◽  
1966 ◽  
Vol 195 (12) ◽  
pp. 1005-1009 ◽  
Author(s):  
D. J. Fernbach
Keyword(s):  
Wilms Tumor

Role of the allergist in diagnosis and management of patients with uveitis

JAMA ◽  
1966 ◽  
Vol 195 (3) ◽  
pp. 167-172 ◽  
Author(s):  
T. E. Van Metre
Keyword(s):  
Diagnosis And Management

The power of norms to sway fused group members

2018 ◽  
Vol 41 ◽  
Author(s):  
Winnifred R. Louis ◽  
Craig McGarty ◽  
Emma F. Thomas ◽  
Catherine E. Amiot ◽  
Fathali M. Moghaddam
Keyword(s):  
Evolutionary Anthropology ◽  
Normative Systems ◽  
Violent Extremism ◽  
Identity Fusion ◽  
Group Members

AbstractWhitehouse adapts insights from evolutionary anthropology to interpret extreme self-sacrifice through the concept of identity fusion. The model neglects the role of normative systems in shaping behaviors, especially in relation to violent extremism. In peaceful groups, increasing fusion will actually decrease extremism. Groups collectively appraise threats and opportunities, actively debate action options, and rarely choose violence toward self or others.

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