Electrophilic Addition and Substitution Reactions of Bis((trifluoromethyl)sulfonyl)amide and Its N-Chloro Derivative

1994 ◽  
Vol 33 (15) ◽  
pp. 3281-3288 ◽  
Author(s):  
Ashwani Vij ◽  
Yuan Y. Zheng ◽  
Robert L. Kirchmeier ◽  
Jean'ne M. Shreeve
Keyword(s):  
Electrophilic Addition ◽  
Substitution Reactions ◽  
Chloro Derivative

scholarly journals Studies of Polarized Ethylenes. IX. Electrophilic Addition and Substitution Reactions.

1978 ◽  
Vol 32b ◽  
pp. 141-148 ◽  
Author(s):  
Sören Karlsson ◽  
Jan Sandström ◽  
Kurt Torssell ◽  
Rolf Servin ◽  
Curt R. Enzell ◽  
...  
Keyword(s):  
Electrophilic Addition ◽  
Substitution Reactions

[Ge9{M(CO)5}3]4−: electrophilic addition of M(CO)5and [E9]4−Zintl anions (M = Cr, Mo, W)

2017 ◽  
Vol 46 (21) ◽  
pp. 6839-6842 ◽  
Author(s):  
Lulu Wang ◽  
Yi Wang ◽  
Zhenyu Li ◽  
Huapeng Ruan ◽  
Li Xu
Keyword(s):  
Nucleophilic Substitution ◽  
Electrophilic Addition ◽  
Core Structure ◽  
The Novel ◽  
Substitution Reactions ◽  
Nucleophilic Substitution Reactions ◽  
Trigonal Prismatic

Electrophilic addition of M(CO)5and [E9]n−at the three capping sites was achieved by the nucleophilic substitution reactions of K4Ge9and M(CO)6, which produced the novelC3h-[Ge9{M(CO)5}3]4−(M = Cr,1; Mo,2; W,3) exhibiting a perfect tricapped trigonal prismatic core structure.

ChemInform Abstract: SYNTHESIS OF SALTS OF 2,4-DINITRO-3-HEXENE-1,6-DIOLS AND THEIR BEHAVIOR IN ELECTROPHILIC ADDITION (SUBSTITUTION) REACTIONS

1982 ◽  
Vol 13 (13) ◽  
Author(s):  
L. YA. ZAGIBALOVA ◽  
E. S. LIPINA ◽  
G. A. BERKOVA ◽  
T. YA. PAPERNO ◽  
V. V. PEREKALIN ◽  
...  
Keyword(s):  
Electrophilic Addition ◽  
Substitution Reactions

Fluorinated tricyclic neuroleptics with prolonged action: 3-Fluoro-8-trifluoromethyl derivatives of 10-(4-methylpiperazino)- and 10-[4-(2-hydroxyethyl)piperazino]-10,11-dihydrodibenzo-[b,f]thiepin

1981 ◽  
Vol 46 (1) ◽  
pp. 118-140 ◽  
Author(s):  
Karel Šindelář ◽  
Miroslav Ryska ◽  
Jiří Holubek ◽  
Emil Svátek ◽  
Jiřina Metyšová ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Prolonged Action ◽  
Substitution Reactions ◽  
Isolation And Characterization ◽  
Chloro Derivative ◽  
Derivatives Of ◽  
Enol Ester ◽  
Preparative Purpose ◽  
Hydroxyethyl Piperazine

A reaction of (4-fluoro-2-iodophenyl)acetic acid with 4-(trifluoromethyl)thiophenol gave the acid VIII which was cyclized with the reagent consisting from methanesulphonic acid and phosphorus pentoxide and afforded the methanesulphonic enol ester XIX. The alkaline hydrolysis resulted in 3-fluoro-8-trifluoromethyldibenzo[b,f]thiepin-10(11H)-one (XVI) which was transformed via the alcohol XXIV to the chloro derivative XXV. Substitution reactions with 1-methylpiperazine and 1-(2-hydroxyethyl)piperazine resulted in the title compounds IV and V. These products are very potent cataleptic neuroleptic agents with a prolongation of duration of the effects comparable to that of isofloxythepin and tefluthixol. A series of further synthetic experiments aimed at alternative syntheses of the acid VIII and the ketone XVI; their results were mostly not of use for preparative purpose but they led to isolation and characterization of a series of interesting heterocyclic products (XVII, XVIII, XXII, XXIII, XXIX-XXXI, XXXVI-XXXIX).

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