Microwave-Assisted Synthesis of 5-Phenyl-2-hydroxyacetophenone Derivatives by a Green Suzuki Coupling Reaction

2014 ◽  
Vol 92 (3) ◽  
pp. 575-578 ◽  
Author(s):  
Pedro Soares ◽  
Carlos Fernandes ◽  
Daniel Chavarria ◽  
Fernanda Borges
Keyword(s):  
Coupling Reaction ◽  
Suzuki Coupling ◽  
Microwave Assisted Synthesis ◽  
Suzuki Coupling Reaction ◽  
Microwave Assisted

scholarly journals A Highly Efficient Microwave-Assisted Suzuki Coupling Reaction of Aryl Perfluorooctylsulfonates with Boronic Acids

2004 ◽  
Vol 6 (9) ◽  
pp. 1473-1476 ◽  
Author(s):  
Wei Zhang ◽  
Christine Hiu-Tung Chen ◽  
Yimin Lu ◽  
Tadamichi Nagashima
Keyword(s):  
Coupling Reaction ◽  
Suzuki Coupling ◽  
Boronic Acids ◽  
Suzuki Coupling Reaction ◽  
Microwave Assisted ◽  
Highly Efficient

scholarly journals Microwave-Assisted Regioselective Suzuki Coupling of 2,4-Dichloropyrimidines with Aryl and Heteroaryl Boronic Acids

Catalysts ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 439
Author(s):  
Ana Dolšak ◽  
Kristjan Mrgole ◽  
Matej Sova
Keyword(s):  
Low Cost ◽  
Coupling Reaction ◽  
Suzuki Coupling ◽  
Boronic Acids ◽  
Catalyst Loading ◽  
Reaction Conditions ◽  
Suzuki Coupling Reaction ◽  
Microwave Assisted ◽  
Synthetic Procedure ◽  
Low Catalyst Loading

Suzuki coupling reaction has been often used for the preparation of a diverse set of substituted pyrimidines. In this study, the Suzuki coupling of 2,4-dichloropyrimidines with aryl and heteroaryl boronic acids was investigated. A thorough screening of reaction conditions and the use of microwave irradiation led to a very efficient and straightforward synthetic procedure providing C4-substituted pyrimidines in good to excellent yields. Short reaction time (15 min) and extremely low catalyst loading (0.5 mol%) are the main advantages of our tetrakis(triphenylphosphine)palladium(0) catalyzed microwave-assisted procedure, which could be used for quick and low-cost regioselective preparation of substituted pyrimidine rings.

Preparation and characterization of glycopolymers with biphenyl spacers via Suzuki coupling reaction

2021 ◽  
Author(s):  
Hirokazu Seto ◽  
Takumi Tono ◽  
Akiko Nagaoka ◽  
Mai Yamamoto ◽  
Yumiko Hirohashi ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Suzuki Coupling ◽  
Side Chains ◽  
Suzuki Coupling Reaction ◽  
Reactant Concentration

Poly(vinylbiphenyl)s bearing glycoside ligands at the side chains were prepared using the Suzuku coupling reaction. Effects of glycoside reactant concentration, halide species, glycoside species, and catalyst species on the incorporation...

ChemInform Abstract: Design and Synthesis of Potential β-Sheet Nucleators via Suzuki Coupling Reaction.

ChemInform ◽  
2008 ◽  
Vol 39 (15) ◽  
Author(s):  
Elisa Perissutti ◽  
Francesco Frecentese ◽  
Antonio Lavecchia ◽  
Ferdinando Fiorino ◽  
Beatrice Severino ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Suzuki Coupling ◽  
Suzuki Coupling Reaction ◽  
Design And Synthesis ◽  
Β Sheet

An Efficient Route to Biaryl Bisbenzocyclobutene Monomers Based on Suzuki Coupling Reaction at Room Temperature.

ChemInform ◽  
2005 ◽  
Vol 36 (38) ◽  
Author(s):  
Jun-xiao Yang ◽  
Kuo-yan Ma ◽  
Fang-hua Zhu ◽  
Wen Chen ◽  
Bo Li ◽  
...  
Keyword(s):  
Room Temperature ◽  
Coupling Reaction ◽  
Suzuki Coupling ◽  
Suzuki Coupling Reaction ◽  
Efficient Route

The Synthesis and Catalytic Application of a New Class of Imprinted Silica

2003 ◽  
Vol 787 ◽  
Author(s):  
John D. Bass ◽  
Sandra L. Anderson ◽  
Alexander Katz
Keyword(s):  
Rational Design ◽  
Chemical Reactivity ◽  
Phenylboronic Acid ◽  
Coupling Reaction ◽  
Suzuki Coupling ◽  
Outer Sphere ◽  
Suzuki Coupling Reaction ◽  
New Class ◽  
Catalytic Application ◽  
Rate Acceleration

AbstractThe effect of chemical environment surrounding a synthetic heterogeneous catalyst active site is investigated using the hydrophilic imprinting of silica. Two model reaction systems have been used for this study: (i) Knoevenagel condensation of 3-nitrobenzaldehyde and malononitrile and (ii) Suzuki coupling of bromobenzene and phenylboronic acid. Using a catalyst in which isolated imprinted amines are surrounded by an acidic silanol-rich environment led to rate accelerations of over 120-fold relative to catalysts in which the amines are surrounded by a hydrophobic environment consisting of trimethylsilyl functional groups for system (i). This result parallels our previous study on the effect of the outer sphere composition on rate acceleration of Knoevenagel reactions using isophthalaldehyde as the aldehyde reactant. We also extended our method for the hydrophilic imprinting of bulk silica to organometallic systems, by successfully synthesizing a tethered palladium complex within the imprinted pocket. This material was used as an active catalyst for (ii). Our results show that a hydrophobic framework environment results in higher initial turnover frequencies than an acidic silanol-rich framework for the Suzuki coupling reaction of bromobenzene and phenylboronic acid, albeit with a lower overall effect than observed in the Knoevenagel system (i). Altogether, these results demonstrate the control of chemical reactivity via the rational design of the outer sphere using an imprinting approach.

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