scholarly journals A Highly Efficient Microwave-Assisted Suzuki Coupling Reaction of Aryl Perfluorooctylsulfonates with Boronic Acids

2004 ◽  
Vol 6 (9) ◽  
pp. 1473-1476 ◽  
Author(s):  
Wei Zhang ◽  
Christine Hiu-Tung Chen ◽  
Yimin Lu ◽  
Tadamichi Nagashima
Keyword(s):  
Coupling Reaction ◽  
Suzuki Coupling ◽  
Boronic Acids ◽  
Suzuki Coupling Reaction ◽  
Microwave Assisted ◽  
Highly Efficient

scholarly journals Microwave-Assisted Regioselective Suzuki Coupling of 2,4-Dichloropyrimidines with Aryl and Heteroaryl Boronic Acids

Catalysts ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 439
Author(s):  
Ana Dolšak ◽  
Kristjan Mrgole ◽  
Matej Sova
Keyword(s):  
Low Cost ◽  
Coupling Reaction ◽  
Suzuki Coupling ◽  
Boronic Acids ◽  
Catalyst Loading ◽  
Reaction Conditions ◽  
Suzuki Coupling Reaction ◽  
Microwave Assisted ◽  
Synthetic Procedure ◽  
Low Catalyst Loading

Suzuki coupling reaction has been often used for the preparation of a diverse set of substituted pyrimidines. In this study, the Suzuki coupling of 2,4-dichloropyrimidines with aryl and heteroaryl boronic acids was investigated. A thorough screening of reaction conditions and the use of microwave irradiation led to a very efficient and straightforward synthetic procedure providing C4-substituted pyrimidines in good to excellent yields. Short reaction time (15 min) and extremely low catalyst loading (0.5 mol%) are the main advantages of our tetrakis(triphenylphosphine)palladium(0) catalyzed microwave-assisted procedure, which could be used for quick and low-cost regioselective preparation of substituted pyrimidine rings.

A Mild Palladium-Catalyzed Suzuki Coupling Reaction of Quinoline Carboxylates with Boronic Acids

2011 ◽  
Vol 353 (10) ◽  
pp. 1671-1675 ◽  
Author(s):  
Wenjie Li ◽  
Joe J. Gao ◽  
Yongda Zhang ◽  
Wenjun Tang ◽  
Heewon Lee ◽  
...  
Keyword(s):  
Coupling Reaction ◽  
Suzuki Coupling ◽  
Boronic Acids ◽  
Suzuki Coupling Reaction ◽  
Palladium Catalyzed
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