Vesicle Stability and Dynamics: An Undergraduate Biochemistry Laboratory

2014 ◽  
Vol 91 (8) ◽  
pp. 1228-1231 ◽  
Author(s):  
Cristina Del Bianco ◽  
Domenica Torino ◽  
Sheref S. Mansy
Keyword(s):  
Vesicle Stability

scholarly journals EP-2019 Does the use of an endorectal balloon improve seminal vesicle stability for prostate radiotherapy?

2019 ◽  
Vol 133 ◽  
pp. S1107
Author(s):  
S. Chin ◽  
A. McWilliam ◽  
D. Brand ◽  
S. Barton ◽  
Y.P. Song ◽  
...  
Keyword(s):  
Seminal Vesicle ◽  
Prostate Radiotherapy ◽  
Endorectal Balloon ◽  
Vesicle Stability

scholarly journals Hybrid Vesicle Stability under Sterilisation and Preservation Processes Used in the Manufacture of Medicinal Formulations

2020 ◽  
Author(s):  
Rashmi Seneviratne ◽  
Lars J.C. Jeuken ◽  
Michael Rappolt ◽  
Paul A. Beales
Keyword(s):  
Block Copolymer ◽  
Colloidal Stability ◽  
Size Distributions ◽  
Process Stability ◽  
Vesicle Size ◽  
Industry Applications ◽  
Poly Ethylene ◽  
The Stability ◽  
Future Work ◽  
Vesicle Stability

Sterilisation and preservation of vesicle formulations are an important consideration for their viable manufacture for industry applications, particular those intended for medicinal use. Here we undertake an initial investigation of the stability of hybrid lipid – block copolymer vesicles to common sterilisation and preservation processes, with particular interest in how the block copolymer component might tune vesicle stability. We investigate two sizes of polybutadiene-block-poly(ethylene oxide) polymers (PBd12-PEO11 and PBd22-PEO14) mixed with the phospholipid POPC considering the encapsulation stability of a fluorescent cargo and the colloidal stability of vesicle size distributions. We find that autoclaving and lyophilisation cause complete loss of encapsulation stability under the conditions studied here. Filtering through 200 nm pores appears to be viable for sterilisation for all vesicle compositions with comparatively low release of encapsulated cargo, even for vesicle size distributions which extend beyond the 200 nm filter pore size. Freeze-thaw of vesicles also shows promise for preservation of hybrid vesicles with high block copolymer content. We discuss the process stability of hybrid vesicles in terms of the complex mechanical interplay between bending resistance, stretching elasticity and lysis strain of these membranes and propose strategies for future work to further enhance the process stability of these vesicle formulations.

Development of curcumin-loaded composite phospholipid ethosomes for enhanced skin permeability and vesicle stability

2021 ◽  
Vol 592 ◽  
pp. 119936
Author(s):  
Yu Li ◽  
Fei Xu ◽  
Xiang Li ◽  
Si-Ying Chen ◽  
Lin-Yu Huang ◽  
...  
Keyword(s):  
Skin Permeability ◽  
Vesicle Stability

scholarly journals Reconciling Ligase Ribozyme Activity with Fatty Acid Vesicle Stability

Life ◽  
2014 ◽  
Vol 4 (4) ◽  
pp. 929-943 ◽  
Author(s):  
Fabrizio Anella ◽  
Christophe Danelon
Keyword(s):  
Fatty Acid ◽  
Vesicle Stability

Investigations of the influence of liposome composition on vesicle stability and drug transfer in human plasma: a transfer study

2016 ◽  
Vol 28 (1) ◽  
pp. 22-34 ◽  
Author(s):  
Stephan Holzschuh ◽  
Kathrin Kaeß ◽  
Guilherme Volpe Bossa ◽  
Christiane Decker ◽  
Alfred Fahr ◽  
...  
Keyword(s):  
Human Plasma ◽  
Drug Transfer ◽  
Transfer Study ◽  
Vesicle Stability

scholarly journals Plasma membrane aquaporins mediates vesicle stability in broccoli

PLoS ONE ◽  
2018 ◽  
Vol 13 (2) ◽  
pp. e0192422 ◽  
Author(s):  
Maria del Carmen Martínez-Ballesta ◽  
Pablo García-Gomez ◽  
Lucía Yepes-Molina ◽  
Angel L. Guarnizo ◽  
José A. Teruel ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Vesicle Stability
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