Determination of p-aminobenzoic acid in urine: A student laboratory experiment

1974 ◽  
Vol 51 (4) ◽  
pp. 275
Author(s):  
Richard E. Gammans ◽  
James T. Stewart
Keyword(s):  
Laboratory Experiment ◽  
Aminobenzoic Acid ◽  
Student Laboratory

Simultaneous Spectrophotometric Determination of Salbutamol by Coupling with Diazotized 4-Aminobenzoic acid

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Hind Hadi ◽  
Gufran Salim
Keyword(s):  
Pharmaceutical Preparations ◽  
Coupling Reaction ◽  
Dosage Forms ◽  
Water Soluble ◽  
Trace Determination ◽  
Aminobenzoic Acid ◽  
Optimum Conditions ◽  
Colored Product ◽  
Versus Concentration

A simple, rapid and sensitive spectrophotmetric method for trace determination of salbutamol (SAL) in aqueous solution and in pharmaceutical preparations is described. The method is based on the diazotization coupling reaction of the intended compound with 4-amino benzoic acid (ABA) in alkaline medium to form an intense orange, water soluble dye that is stable and shows maximum absorption at 410 nm. A graph of absorbance versus concentration indicates that Beer’s law is obeyed over the concentration range of 0.5-30 ppm, with a molar absorbtivity 3.76×104 L.mol-1 .cm-1 depending on the concentration of SAL. The optimum conditions and stability of the colored product have been investigated and the method was applied successfully to the determination of SAL in dosage forms.

Simultaneous determination of procaine and para-aminobenzoic acid by LC–MS/MS method

2007 ◽  
Vol 847 (2) ◽  
pp. 224-230 ◽  
Author(s):  
Mugunthu R. Dhananjeyan ◽  
Crystal Bykowski ◽  
Jill A. Trendel ◽  
Jeffrey G. Sarver ◽  
Howard Ando ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Aminobenzoic Acid
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