Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes

2004 ◽  
Vol 104 (9) ◽  
pp. 3947-3980 ◽  
Author(s):  
Bernard Meunier ◽  
Samuël P. de Visser ◽  
Sason Shaik
ChemInform ◽  
2004 ◽  
Vol 35 (46) ◽  
Author(s):  
Bernard Meunier ◽  
Samuel P. de Visser ◽  
Sason Shaik

2011 ◽  
Vol 7 (2) ◽  
pp. 327-339 ◽  
Author(s):  
Sason Shaik ◽  
Petr Milko ◽  
Patric Schyman ◽  
Dandamudi Usharani ◽  
Hui Chen

2010 ◽  
Vol 63 (11) ◽  
pp. 1505 ◽  
Author(s):  
Richard H. Fish

A 37 year perspective on bioorganometallic chemistry studies, which included metabolism of organotin compounds with cytochrome P450 enzymes, and their biomimics; reactions of organorhodium aqua complexes with nucleobases, nucleosides, and nucleotides; supramolecular organorhodium-nucleobase complexes as hosts for aromatic amino acid and aromatic carboxylic acid guests; regioselective reduction of NAD+ biomimics with an organorhodium hydride; tandem catalysis of an organorhodium hydride reduction to provide a 1,4-NADH biomimic for horse liver dehydrogenase stereoselective reduction of achiral ketones to chiral alcohols, and oxidation reactions with cytochrome P450 enzymes; and organorhodium-hydroxytamoxifen pharmaceuticals, will be presented. Each of these areas of bioorganometallic chemistry will be briefly discussed in this personal synopsis of the new, important, and exciting field of bioorganometallic chemistry, and its impact on metal-based drug research.


1958 ◽  
Vol 14 (5_6) ◽  
pp. 357-360
Author(s):  
K. C. Grover ◽  
R. C. Mehrotra

1958 ◽  
Vol 14 (5_6) ◽  
pp. 345-356 ◽  
Author(s):  
K. C. Grover ◽  
R. C. Mehrotra

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