Identification of Non-Macrocyclic Small Molecule Inhibitors against the NS3/4A Serine Protease of Hepatitis C Virus through in Silico Screening

2012 ◽  
Vol 52 (8) ◽  
pp. 2245-2256 ◽  
Author(s):  
Rima Chaudhuri ◽  
Hyun Lee ◽  
Lena Truong ◽  
Jaime Torres ◽  
Kavankumar Patel ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Serine Protease ◽  
Small Molecule ◽  
In Silico ◽  
Small Molecule Inhibitors ◽  
In Silico Screening

Potent and selective small molecule NS3 serine protease inhibitors of Hepatitis C virus with dichlorocyclopropylproline as P2 residue

2008 ◽  
Vol 16 (4) ◽  
pp. 1874-1883 ◽  
Author(s):  
Kevin X. Chen ◽  
Bancha Vibulbhan ◽  
Weiying Yang ◽  
Kuo-Chi Cheng ◽  
Rong Liu ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Serine Protease ◽  
Protease Inhibitors ◽  
Small Molecule ◽  
Serine Protease Inhibitors

scholarly journals Interdomain Communication in Hepatitis C Virus Polymerase Abolished by Small Molecule Inhibitors Bound to a Novel Allosteric Site

2005 ◽  
Vol 280 (33) ◽  
pp. 29765-29770 ◽  
Author(s):  
Stefania Di Marco ◽  
Cinzia Volpari ◽  
Licia Tomei ◽  
Sergio Altamura ◽  
Steven Harper ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Allosteric Site ◽  
Interdomain Communication

Peptide-based inhibitors of hepatitis C virus full-length NS3 (protease-helicase/NTPase): model compounds towards small molecule inhibitors

2003 ◽  
Vol 11 (13) ◽  
pp. 2955-2963 ◽  
Author(s):  
Karin Oscarsson ◽  
Anton Poliakov ◽  
Stefan Oscarson ◽  
U.Helena Danielson ◽  
Anders Hallberg ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Full Length ◽  
Model Compounds ◽  
Ns3 Protease

Identification of novel small molecule inhibitors against the NS3/4A protease of hepatitis C virus genotype 4a

2019 ◽  
Vol 24 (37) ◽  
pp. 4484-4491 ◽  
Author(s):  
Sara M. El-Sayed ◽  
Mohamed A.M. Ali ◽  
Bahaa El-Dien M. El- Gendy ◽  
Samar S. Dandash ◽  
Yvette Issac ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Small Molecule ◽  
Small Molecule Inhibitors ◽  
Virus Genotype

scholarly journals New small molecule inhibitors of hepatitis C virus

2009 ◽  
Vol 19 (24) ◽  
pp. 6926-6930 ◽  
Author(s):  
Wanguo Wei ◽  
Cuifang Cai ◽  
Smitha Kota ◽  
Virginia Takahashi ◽  
Feng Ni ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Small Molecule ◽  
Small Molecule Inhibitors

ChemInform Abstract: New Small Molecule Inhibitors of Hepatitis C Virus.

ChemInform ◽  
2010 ◽  
Vol 41 (16) ◽  
Author(s):  
Wanguo Wei ◽  
Cuifang Cai ◽  
Smitha Kota ◽  
Virginia Takahashi ◽  
Feng Ni ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Small Molecule ◽  
Small Molecule Inhibitors
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