Solid-Phase Synthesis of Biologically Active Benzoannelated Nitrogen Heterocycles: An Update

2009 ◽  
Vol 11 (2) ◽  
pp. 175-197 ◽  
Author(s):  
Carmen Gil ◽  
Stefan Bräse
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Nitrogen Heterocycles ◽  
Biologically Active ◽  
Phase Synthesis

Solid phase synthesis of somatostatin-28 II. A new biologically active octacosapeptide from anglerfish pancreatic islets

1986 ◽  
Vol 140 (2) ◽  
pp. 565-573 ◽  
Author(s):  
Pierre Nicolas ◽  
Antoine Delfour ◽  
Hamadi Boussetta ◽  
Alain Morel ◽  
Mohamed Rholam ◽  
...  
Keyword(s):  
Pancreatic Islets ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Biologically Active ◽  
Phase Synthesis

A modified benzhydrylamine - A useful handle reagent for Fmoc based solid phase synthesis of peptide amides

1988 ◽  
Vol 53 (11) ◽  
pp. 2791-2800 ◽  
Author(s):  
Susumu Funakoshi ◽  
Eigoro Murayama ◽  
Lili Guo ◽  
Nobutaka Fujii ◽  
Haruaki Yajima
Keyword(s):  
Propionic Acid ◽  
Arginine Vasopressin ◽  
Trifluoroacetic Acid ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Biologically Active ◽  
Molar Ratio ◽  
Phase Synthesis ◽  
Active Peptide ◽  
Biologically Active Peptide

Usefulness of a dimethoxybenzhydrylamine derivative, 3-(3-(Fmoc-amino-4-methoxyphenylmethyl)-4-methoxyphenyl)propionic acid, for Fmoc-based solid phase synthesis of peptide amides was demonstrated by preparation of three biologically active peptide amides, i.e. tetragastrin, neuromedin B and [8-arginine]vasopressin. 1M trimethylsilyl bromide-thioanisole (molar ratio 1 : 1) in trifluoroacetic acid was recommended as a deprotecting reagent for releasing the peptide amides from the resin.

Solid phase synthesis of biologically active antigenic peptides for T-cells

Peptides ◽  
1988 ◽  
pp. 524-526
Author(s):  
Lisa A. Casten ◽  
Pravin Kaumaya ◽  
Mark S. Anderson ◽  
John A. Smith ◽  
Susan K. Pierce
Keyword(s):  
T Cells ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Biologically Active ◽  
Antigenic Peptides ◽  
Phase Synthesis
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