scholarly journals Structure–Property Evaluation of Thermally and Chemically Gelling Injectable Hydrogels for Tissue Engineering

2012 ◽  
Vol 13 (9) ◽  
pp. 2821-2830 ◽  
Author(s):  
Adam K. Ekenseair ◽  
Kristel W. M. Boere ◽  
Stephanie N. Tzouanas ◽  
Tiffany N. Vo ◽  
F. Kurtis Kasper ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Structure Property ◽  
Injectable Hydrogels ◽  
Property Evaluation

scholarly journals Significance of Crosslinking Approaches in the Development of Next Generation Hydrogels for Corneal Tissue Engineering

Pharmaceutics ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 319
Author(s):  
Promita Bhattacharjee ◽  
Mark Ahearne
Keyword(s):  
Tissue Engineering ◽  
Chemical Structure ◽  
Biochemical Properties ◽  
Corneal Tissue ◽  
Future Prospects ◽  
Chemical Additives ◽  
Injectable Hydrogels ◽  
Corneal Regeneration ◽  
Key Factor ◽  
Fuchs Endothelial Dystrophy

Medical conditions such as trachoma, keratoconus and Fuchs endothelial dystrophy can damage the cornea, leading to visual deterioration and blindness and necessitating a cornea transplant. Due to the shortage of donor corneas, hydrogels have been investigated as potential corneal replacements. A key factor that influences the physical and biochemical properties of these hydrogels is how they are crosslinked. In this paper, an overview is provided of different crosslinking techniques and crosslinking chemical additives that have been applied to hydrogels for the purposes of corneal tissue engineering, drug delivery or corneal repair. Factors that influence the success of a crosslinker are considered that include material composition, dosage, fabrication method, immunogenicity and toxicity. Different crosslinking techniques that have been used to develop injectable hydrogels for corneal regeneration are summarized. The limitations and future prospects of crosslinking strategies for use in corneal tissue engineering are discussed. It is demonstrated that the choice of crosslinking technique has a significant influence on the biocompatibility, mechanical properties and chemical structure of hydrogels that may be suitable for corneal tissue engineering and regenerative applications.

Effect of pouring temperature on A356-TiB2 MMCs cast in sand and permanent moulds by in-situ method

2016 ◽  
Vol 25 (5-6) ◽  
pp. 165-169
Author(s):  
C. Rajaravi ◽  
P.R. Lakshminarayanan
Keyword(s):  
Evaluation Studies ◽  
Physical And Mechanical Properties ◽  
Xrd Analysis ◽  
Matrix Composites ◽  
Structure Property ◽  
Pouring Temperature ◽  
Matrix Metal ◽  
Property Evaluation ◽  
The Matrix

AbstractThe paper describes a different condition of pouring temperature by sand and permanent mould to produce A356-6 wt% TiB2 metal matrix composites by in-situ method salt metal reaction route. The observation of SEM micrographs shows particle distribution of the TiB2 and it appears in hexagonal shape in Al matrix. The results of X-ray diffraction (XRD) analysis confirmed the formation of those TiB2 particulates and the results showed TiB2 particles are homogeneously dispersed throughout the matrix metal. Subsequent structure-property evaluation studies indicated sub-micron size reinforcement of in-situ formed TiB2 particles with improved physical and mechanical properties as compared to sand and permanent mould of Al-TiB2 composites. From, the permanent mould Al-TiB2 composite has an advantage of increase the properties over sand mould Al-TiB2 composite.

Temperature- and pH-responsive chitosan-based injectable hydrogels for bone tissue engineering

2020 ◽  
Vol 111 ◽  
pp. 110862 ◽  
Author(s):  
K. Lavanya ◽  
S. Viji Chandran ◽  
K. Balagangadharan ◽  
N. Selvamurugan
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Ph Responsive ◽  
Injectable Hydrogels

Enzymatically-crosslinked injectable hydrogels based on biomimetic dextran–hyaluronic acid conjugates for cartilage tissue engineering

Biomaterials ◽  
2010 ◽  
Vol 31 (11) ◽  
pp. 3103-3113 ◽  
Author(s):  
R. Jin ◽  
L.S. Moreira Teixeira ◽  
P.J. Dijkstra ◽  
C.A. van Blitterswijk ◽  
M. Karperien ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue ◽  
Injectable Hydrogels

scholarly journals Injectable hydrogels for cartilage and bone tissue engineering

Bone Research ◽  
2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Mei Liu ◽  
Xin Zeng ◽  
Chao Ma ◽  
Huan Yi ◽  
Zeeshan Ali ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Injectable Hydrogels

Polymer structure-property requirements for stereolithographic 3D printing of soft tissue engineering scaffolds

Biomaterials ◽  
2017 ◽  
Vol 140 ◽  
pp. 170-188 ◽  
Author(s):  
Ryan J. Mondschein ◽  
Akanksha Kanitkar ◽  
Christopher B. Williams ◽  
Scott S. Verbridge ◽  
Timothy E. Long
Keyword(s):  
Tissue Engineering ◽  
Soft Tissue ◽  
3D Printing ◽  
Polymer Structure ◽  
Structure Property ◽  
Tissue Engineering Scaffolds ◽  
Soft Tissue Engineering

scholarly journals Gellan Gum Injectable Hydrogels for Cartilage Tissue Engineering Applications: In Vitro Studies and Preliminary In Vivo Evaluation

2010 ◽  
Vol 16 (1) ◽  
pp. 343-353 ◽  
Author(s):  
João T. Oliveira ◽  
Tírcia C. Santos ◽  
Luís Martins ◽  
Ricardo Picciochi ◽  
Alexandra P. Marques ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cartilage Tissue Engineering ◽  
Gellan Gum ◽  
In Vitro Studies ◽  
Cartilage Tissue ◽  
Engineering Applications ◽  
In Vivo Evaluation ◽  
Injectable Hydrogels

One-step cross-linked injectable hydrogels with tunable properties for space-filling scaffolds in tissue engineering

RSC Advances ◽  
2015 ◽  
Vol 5 (51) ◽  
pp. 40820-40830 ◽  
Author(s):  
Jian-feng Pan ◽  
Heng-feng Yuan ◽  
Chang-an Guo ◽  
Jia Liu ◽  
Xiao-hua Geng ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Space Filling ◽  
Injectable Hydrogels ◽  
Tunable Properties ◽  
One Step

One-step cross-linked injectable hydrogels are prepared through Schiff-based reaction with tunable properties for space-filling scaffolds.

Micromechanical characterization of soft, biopolymeric hydrogels: stiffness, resilience, and failure

Soft Matter ◽  
2018 ◽  
Vol 14 (18) ◽  
pp. 3478-3489 ◽  
Author(s):  
Shruti Rattan ◽  
Linqing Li ◽  
Hang Kuen Lau ◽  
Alfred J. Crosby ◽  
Kristi L. Kiick
Keyword(s):  
Tissue Engineering ◽  
Local Structure ◽  
Structure Property ◽  
Detailed Understanding ◽  
Structure Property Relationships ◽  
Micromechanical Characterization

Detailed understanding of the local structure–property relationships in soft biopolymeric hydrogels can be instrumental for applications in regenerative tissue engineering.

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