Dually Responsive Injectable Hydrogel Prepared by In Situ Cross-Linking of Glycol Chitosan and Benzaldehyde-Capped PEO-PPO-PEO

2010 ◽  
Vol 11 (4) ◽  
pp. 1043-1051 ◽  
Author(s):  
Caixia Ding ◽  
Lingling Zhao ◽  
Fuyong Liu ◽  
Jun Cheng ◽  
Jingxia Gu ◽  
...  
Keyword(s):  
Cross Linking ◽  
Glycol Chitosan ◽  
Injectable Hydrogel

An injectable hydrogel formed by in situ cross-linking of glycol chitosan and multi-benzaldehyde functionalized PEG analogues for cartilage tissue engineering

2015 ◽  
Vol 3 (7) ◽  
pp. 1268-1280 ◽  
Author(s):  
Luping Cao ◽  
Bin Cao ◽  
Chengjiao Lu ◽  
Guowei Wang ◽  
Lin Yu ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue ◽  
Cross Linking ◽  
Glycol Chitosan ◽  
Injectable Hydrogels ◽  
Injectable Hydrogel ◽  
Cross Linker ◽  
Aldehyde Groups

A novel PEG analogue, poly(EO-co-Gly)-CHO, that possesses multiple aldehyde groups is designed and synthesized, and then is used as a cross-linker to react with glycol chitosan to create injectable hydrogels.

scholarly journals Interfacial engineering of lithium‐polymer batteries with in situ UV cross‐linking

InfoMat ◽  
2021 ◽  
Author(s):  
Ramin Rojaee ◽  
Samuel Plunkett ◽  
Md Golam Rasul ◽  
Meng Cheng ◽  
Vahid Jabbari ◽  
...  
Keyword(s):  
Cross Linking ◽  
Lithium Polymer Batteries ◽  
Interfacial Engineering

Stabilization of Peptide-Based Vesicles via in situ Oxygen-Mediated Cross-Linking

2012 ◽  
Vol 12 (9) ◽  
pp. 1220-1231 ◽  
Author(s):  
Adrian Sulistio ◽  
Anton Blencowe ◽  
Jiapei Wang ◽  
Gary Bryant ◽  
Xiaoqing Zhang ◽  
...  
Keyword(s):  
Cross Linking

Palladium immobilized on in situ cross-linked chitosan superfine fibers for catalytic application in an aqueous medium

2018 ◽  
Vol 42 (13) ◽  
pp. 11023-11030 ◽  
Author(s):  
Lulu Liang ◽  
Li Nie ◽  
Minjuan Jiang ◽  
Fusheng Bie ◽  
Linjun Shao ◽  
...  
Keyword(s):  
Aqueous Medium ◽  
Itaconic Acid ◽  
Cross Linking ◽  
Catalytic Application ◽  
Chitosan Composite

Chitosan composite superfine fibers with a diameter of 321 ± 99 nm were prepared by electrospinning with PEO as the co-spinning polymer and itaconic acid as the in situ cross-linking agent.

Bilayered Antimicrobial Nanofiber Membranes for Wound Dressings via in Situ Cross-Linking Polymerization and Electrospinning

2018 ◽  
Vol 57 (50) ◽  
pp. 17048-17057 ◽  
Author(s):  
Yanping Huang ◽  
Nianhua Dan ◽  
Weihua Dan ◽  
Weifeng Zhao ◽  
Zhongxiang Bai ◽  
...  
Keyword(s):  
Wound Dressings ◽  
Cross Linking ◽  
Nanofiber Membranes

scholarly journals Influence of prolonged formalin fixation of tissue samples on the sensitivity of chromogenic in situ hybridization

2011 ◽  
Vol 23 (6) ◽  
pp. 1212-1216 ◽  
Author(s):  
Meike M. Mostegl ◽  
Barbara Richter ◽  
Nora Dinhopl ◽  
Herbert Weissenböck
Keyword(s):  
In Situ Hybridization ◽  
Nucleic Acid ◽  
Signal Intensity ◽  
Formalin Fixation ◽  
Proteinase K ◽  
Cross Linking ◽  
Fixation Time ◽  
Tissue Samples ◽  
Chromogenic In Situ Hybridization

Chromogenic in situ hybridization (ISH) is a commonly used tool in diagnostic pathology to detect pathogens in formalin-fixed, paraffin-embedded (FFPE) tissue sections. Prolonged formalin fixation time was identified to be a limiting factor for the successful detection of nucleic acid from different pathogens, most probably due to the cross-linking activity of formalin between RNA, DNA, and proteins. Therefore, in the current study, the influence of formalin fixation time on ISH signal intensity of 2 viral ( Porcine circovirus-2 [PCV-2] and Porcine respiratory and reproductive virus [PRRSV]) and 2 protozoal agents ( Cryptosporidium serpentis and Tritrichomonas sp.) was evaluated. Tissue samples were fixed in 7% neutral buffered formaldehyde solution, and at defined intervals, pieces were embedded in paraffin wax and subjected to pathogen-specific ISH. For all 4 pathogens, the signal intensity remained comparable with the starting ISH signal for different periods of fixation (PCV-2: 6 weeks, PRRSV: 23 weeks, C. serpentis: 55 weeks, Tritrichomonas sp.: 53 weeks). Thereafter, the signal started to decline until loss of nucleic acid detection. The influence of increased proteinase K concentrations for inverting the formalin-induced cross-linking activity was examined compared with the standard protocol. With all 4 infectious agents, a 4-fold proteinase K concentration restored the ISH signals to a level comparable with 1 day of fixation. In conclusion, the influence of prolonged formalin fixation on the intensity of detected ISH signal highly depends on the analyzed infectious agent and the pretreatment protocol.

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