Formation of Core/Shell Nanoparticles with a Lipid Core and Their Application as a Drug Delivery System

2005 ◽  
Vol 6 (2) ◽  
pp. 1062-1067 ◽  
Author(s):  
Keun Sang Oh ◽  
Kyung Eun Lee ◽  
Sung Sik Han ◽  
Sun Hang Cho ◽  
Dongmin Kim ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Lipid Core ◽  
Core Shell Nanoparticles

CuS@mSiO2-PEG core–shell nanoparticles as a NIR light responsive drug delivery nanoplatform for efficient chemo-photothermal therapy

2015 ◽  
Vol 44 (22) ◽  
pp. 10343-10351 ◽  
Author(s):  
Xijian Liu ◽  
Qilong Ren ◽  
Fanfan Fu ◽  
Rujia Zou ◽  
Qian Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Photothermal Therapy ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Nir Light ◽  
Core Shell Nanoparticles

A difunctional nanoplatform (CuS@mSiO2-PEG) acted as a NIR light induced photothermal-triggered drug delivery system for efficient chemo-photothermal therapy.

scholarly journals Core–Shell Nanoparticles as an Efficient, Sustained, and Triggered Drug-Delivery System

ACS Omega ◽  
2017 ◽  
Vol 2 (10) ◽  
pp. 6455-6463 ◽  
Author(s):  
Sonal Deshpande ◽  
Sapna Sharma ◽  
Veena Koul ◽  
Neetu Singh
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Core Shell Nanoparticles

scholarly journals Thrombolysis Combined Therapy Using CuS@SiO2-PEG/uPA Nanoparticles

2021 ◽  
Vol 9 ◽  
Author(s):  
Dapeng Fu ◽  
Qingbo Fang ◽  
Fukang Yuan ◽  
Junle Liu ◽  
Heyi Ding ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Combined Therapy ◽  
Drug Loading ◽  
Photothermal Effect ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Core Shell Nanoparticles

Massive hemorrhage caused by the uncontrolled release of thrombolysis drugs is a key issue of thrombolysis therapy in clinical practice. In this study, we report a near-infrared (NIR) light-triggered drug delivery system, i.e., CuS@mSiO2-PEG (CSP) nanoparticles, for the loading of a thrombolytic drug (urokinase plasminogen activators, uPA). CSP nanoparticles with the CuS nanoparticles as photothermal agents and mesoporous SiO2 for the loading of uPA were synthesized using a facile hydrothermal method. The CSP core-shell nanoparticles were demonstrated to possess excellent photothermal performance, exhibiting a photothermal conversion efficiency of up to 52.8%. Due to the mesoporous SiO2 coating, the CSP core-shell nanoparticles exhibited appropriate pore size, high pore volume, and large surface area; thus, they showed great potential to be used as drug carriers. Importantly, the release of uPA from CuS@mSiO2-PEG/uPA (CSPA) carriers can be promoted by the NIR laser irradiation. The drug loading content of uPA for the as-prepared NIR-triggered drug delivery system was calculated to be 8.2%, and the loading efficiency can be determined to be as high as 89.6%. Due to the excellent photothermal effect of CSP nanocarriers, the NIR-triggered drug delivery system can be used for infrared thermal imaging in vivo. The in vivo thrombolysis assessment demonstrated that the NIR-triggered drug delivery system showed excellent thrombolytic ability under the irradiation of an 808 nm laser, showing the combined therapy for thrombolysis. As far as we know, the CSPA core-shell nanoparticles used as NIR-triggered drug delivery systems for thrombolysis have not been reported.

Pluronic-Based Core/Shell Nanoparticles for Drug Delivery and Diagnosis

2013 ◽  
Vol 20 (28) ◽  
pp. 3488-3499 ◽  
Author(s):  
Yon Jung ◽  
Hwanbum Lee ◽  
Jae Kim ◽  
Eun Koo ◽  
Keun Oh ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Core Shell Nanoparticles

NIR-triggered drug delivery system based on Fe3O4-MoS2 core-shell grafted poly(N-vinylcaprolactam): isotherm and kinetics studies

2021 ◽  
pp. 1-15
Author(s):  
Mohammad Javad Khodabakhshi ◽  
Homayon Ahmad Panahi ◽  
Elaheh Konoz ◽  
Alireza Feizbakhsh ◽  
Salimeh Kimiagar
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Core Shell ◽  
Kinetics Studies

Facile and greener hydrothermal honey‐based synthesis of Fe 3 O 4 /Au core/shell nanoparticles for drug delivery applications

2018 ◽  
Vol 120 (4) ◽  
pp. 6624-6631 ◽  
Author(s):  
Elisa Rasouli ◽  
Wan Jeffrey Basirun ◽  
Mohd Rafie Johan ◽  
Majid Rezayi ◽  
Majid Darroudi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Drug Delivery Applications ◽  
Core Shell Nanoparticles

Core-Shell Nanoparticles for Drug Delivery and Molecular Imaging

2007 ◽  
Author(s):  
Sung Kyun Han ◽  
Ree Sun Kim ◽  
Jin Ho Lee ◽  
Giyoong Tae ◽  
Sun Hang Cho ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Molecular Imaging ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Core Shell Nanoparticles
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