scholarly journals Biologically Engineered Protein-graft-Poly(ethylene glycol) Hydrogels:  A Cell Adhesive and Plasmin-Degradable Biosynthetic Material for Tissue Repair

2002 ◽  
Vol 3 (4) ◽  
pp. 710-723 ◽  
Author(s):  
Sven Halstenberg ◽  
Alyssa Panitch ◽  
Simone Rizzi ◽  
Heike Hall ◽  
Jeffrey A. Hubbell
Keyword(s):  
Ethylene Glycol ◽  
Tissue Repair ◽  
Poly Ethylene Glycol ◽  
Cell Adhesive ◽  
A Cell ◽  
Poly Ethylene

An alternative technique for patterning cells on poly(ethylene glycol) diacrylate hydrogels

RSC Advances ◽  
2016 ◽  
Vol 6 (47) ◽  
pp. 40878-40885 ◽  
Author(s):  
Mathew Peter ◽  
Prakriti Tayalia
Keyword(s):  
Ethylene Glycol ◽  
Addition Reaction ◽  
Alternative Technique ◽  
Poly Ethylene Glycol ◽  
Glycol Diacrylate ◽  
Cell Adhesive ◽  
A Cell ◽  
Michael Type Addition ◽  
Poly Ethylene

In this work, a poly(ethylene glycol) diacrylate (PEGDA) hydrogel is patterned with a cell adhesive ligand, that was functionalized with an acrylate group using Michael type addition reaction, thus, circumventing the need for proprietary reagents.

scholarly journals Photo-Cleavable Peptide-Poly(Ethylene Glycol) Conjugate Surfaces for Light-Guided Control of Cell Adhesion

Micromachines ◽  
2020 ◽  
Vol 11 (8) ◽  
pp. 762
Author(s):  
Satoshi Yamaguchi ◽  
Yumi Takasaki ◽  
Shinya Yamahira ◽  
Teruyuki Nagamune
Keyword(s):  
Ethylene Glycol ◽  
Cell Attachment ◽  
Pharmaceutical Research ◽  
Adherent Cells ◽  
Poly Ethylene Glycol ◽  
Light Pattern ◽  
Exposed Region ◽  
Cell Adhesive ◽  
Conjugate Surfaces ◽  
Poly Ethylene

Photo-responsive cell attachment surfaces can simplify patterning and recovery of cells in microdevices for medicinal and pharmaceutical research. We developed a photo-responsive surface for controlling the attachment and release of adherent cells on a substrate under light-guidance. The surface comprises a poly(ethylene glycol) (PEG)-based photocleavable material that can conjugate with cell-adhesive peptides. Surface-bound peptides were released by photocleavage in the light-exposed region, where the cell attachment was subsequently suppressed by the exposed PEG. Simultaneously, cells selectively adhered to the peptide surface at the unexposed microscale region. After culture, the adhered and spread cells were released by exposure to a light with nontoxic dose level. Thus, the present surface can easily create both cell-adhesive and non-cell-adhesive regions on the substrate by single irradiation of the light pattern, and the adhered cells were selectively released from the light-exposed region on the cell micropattern without damage. This study shows that the photo-responsive surface can serve as a facile platform for the remote-control of patterning and recovery of adherent cells in microdevices.

Extracellular Matrix-like Cell-Adhesive Hydrogels from RGD-Containing Poly(ethylene glycol) Diacrylate

2006 ◽  
Vol 39 (4) ◽  
pp. 1305-1307 ◽  
Author(s):  
Junmin Zhu ◽  
Jeffrey A. Beamish ◽  
Chad Tang ◽  
Kandice Kottke-Marchant ◽  
Roger E. Marchant
Keyword(s):  
Extracellular Matrix ◽  
Ethylene Glycol ◽  
Poly Ethylene Glycol ◽  
Glycol Diacrylate ◽  
Cell Adhesive ◽  
Poly Ethylene
Sign in / Sign up

Export Citation Format

Share Document