Comparison of Immunoassay to High-Pressure Liquid Chromatography and Gas Chromatography—Mass Spectrometry Analysis of Pesticides in Surface Water

1997 ◽  
pp. 234-244
Author(s):  
M. I. Selim ◽  
C. Achutan ◽  
J. M. Starr ◽  
T. Jiang ◽  
B. S. Young
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
High Pressure ◽  
Liquid Chromatography ◽  
Surface Water ◽  
High Pressure Liquid Chromatography ◽  
Mass Spectrometry Analysis ◽  
Gas Chromatography Mass Spectrometry ◽  
Spectrometry Analysis ◽  
Chromatography Mass Spectrometry

Identification and Quantitation of Sulfamethazine Metabolites by Liquid Chromatography and Gas Chromatography-Mass Spectrometry

1985 ◽  
Vol 68 (5) ◽  
pp. 1000-1006
Author(s):  
Gaylord D Paulson ◽  
Alva D Mitchell ◽  
Richard G Zaylskie
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Liquid Chromatography ◽  
Mass Spectrometry Analysis ◽  
Gas Chromatography Mass Spectrometry ◽  
Reverse Phase ◽  
Spectrometry Analysis ◽  
Carbon 14 ◽  
Chromatography Mass Spectrometry ◽  
Swine Tissue

Abstract Methods for the identification and quantitation of carbon-14 labeled sulfamethazine [4-amino-iV-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide], W-acetylsulfamethazine, the N4-glucose conjugate of sulfamethazine, and desaminosulfamethazine in swine tissue are described. Tissues are ground and extracted with methanol, and the 14C-labeled compounds are purified by XAD-2 column chromatography and C-18 reverse phase liquid chromatography (LC) and the relabeled compounds are then methylated and identified by gas chromatography- mass spectrometry analysis. Quantitation is accomplished by measuring the amount of 14C-activity that cochromatographs (C-18 reverse phase LC) with reference compounds.

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