Blood Cholinesterase Activity: Inhibition as an Indicator of Adverse Effect

1996 ◽  
pp. 70-78 ◽  
Author(s):  
S. Padilla ◽  
L. Lassiter ◽  
K. Crofton ◽  
V. C. Moser
Keyword(s):  
Adverse Effect ◽  
Cholinesterase Activity ◽  
Activity Inhibition

CHOLINESTERASE INHIBITORS FROM HEARTWOOD OF ARTOCARPUS FULVICORTEX F. M. JARRET (MORACEAE)

2016 ◽  
Vol 78 (6) ◽  
Author(s):  
Masuri Kama Kamaruddin Shah ◽  
Hasnah Mohd Sirat ◽  
Shajarahtunnur Jamil
Keyword(s):  
Spectroscopic Analysis ◽  
Cholinesterase Activity ◽  
Cholinesterase Inhibition ◽  
Dependent Manner ◽  
Activity Inhibition ◽  
Ic50 Values ◽  
Ellman’S Method ◽  
Phytochemical Studies ◽  
First Time ◽  
Dose Dependent

Cholinesterase inhibition activities were screened on crude extracts and isolated compounds of the heartwood of Artocarpus fulvicortex. Phytochemical studies on the heartwood of A. fulvicortex have resulted in the isolation of one flavonoid, one stilbenoid and two triterpenes. Their structures were determined by spectroscopic analysis as catechin (1), oxyresveratrol (2), lupeol-3-acetate (3) and friedelin (4). All isolates were evaluated for the first time for anti-cholinesterase activity. Inhibition of acetylcholinesterase (AChE), tested by Ellman’s method and modified TLC bioautographic assay showed catechin (1) and oxyresvetratrol (2) were active agents with detection limit of 2 mM. The microplate assay was carried out using butyrylcholinesterase (BChe) to further confirmed that catechin (1) and oxyresvetratrol (2) displayed positive cholinesterase activity with IC50 values 50.0 mM and 6.25 mM respectively in dose dependent manner.  

The Resolution and Contrast in Biological Sections Determined by Inelastic and Elastic Scattering

1973 ◽  
Vol 31 ◽  
pp. 224-225
Author(s):  
D. L. Misell
Keyword(s):  
Electron Microscopy ◽  
Adverse Effect ◽  
Elastic Scattering ◽  
Inelastic Scattering ◽  
Amorphous Carbon ◽  
Polymeric Materials ◽  
Chromatic Aberration ◽  
Image Resolution ◽  
Quantitative Estimates ◽  
Elastic Ratio

In the electron microscopy of biological sections the adverse effect of chromatic aberration on image resolution is well known. In this paper calculations are presented for the inelastic and elastic image intensities using a wave-optical formulation. Quantitative estimates of the deterioration in image resolution as a result of chromatic aberration are presented as an alternative to geometric calculations. The predominance of inelastic scattering in the unstained biological and polymeric materials is shown by the inelastic to elastic ratio, I/E, within an objective aperture of 0.005 rad for amorphous carbon of a thickness, t=50nm, typical of biological sections; E=200keV, I/E=16.

Eligible or Ineligible: Determining Adverse Effect

2002 ◽  
Vol 3 (2) ◽  
pp. 26-28
Author(s):  
Linda S. Bowman ◽  
C. Al Bowman ◽  
Rita L. Bailey
Keyword(s):  
Adverse Effect

Additional pulmonary blood flow in Glenn anastomosis has no adverse effect on outcome of later TCPC

2004 ◽  
Vol 52 (S 1) ◽  
Author(s):  
PA Berdat ◽  
A Serraf ◽  
E Belli ◽  
F Lacour-Gayet ◽  
C Planch� ◽  
...  
Keyword(s):  
Adverse Effect ◽  
Blood Flow ◽  
Pulmonary Blood Flow

Bevacizumab efficacy in treatment of brain radiation necrosis

2019 ◽  
Vol 1 (10) ◽  
pp. 15-21
Author(s):  
O. V. Absalyamova ◽  
G. L. Kobiakov ◽  
S. L. Gutorov ◽  
E. R. Vetlova ◽  
S. V. Zolotova ◽  
...  
Keyword(s):  
Adverse Effect ◽  
Vascular Endothelial Growth Factor ◽  
Arteriovenous Malformations ◽  
Radiation Necrosis ◽  
Critical Role ◽  
Common Adverse Effect ◽  
Vascular Endothelial ◽  
Brain Radiation Necrosis ◽  
Endothelial Growth Factor ◽  
Brain Radiation

Radiation therapy (RT) plays an important role in treatment of primary and metastatic CNS tumors and some non-neopiastic conditions (arteriovenous malformations, trigeminal neuralgia). Radiation necrosis (RN) is a common adverse effect of RT. Until recently steroid therapy was used as a main treatment regimen for RN. Mechanisms of RN development are not clear; however, it was shown that vascular endothelial growth factor (VEGF) plays a critical role in its formation. A number of surveys showed efficacy of bevacizumab as an anti-VEGF agent in treatment of RN. Radiation necrosis pathogenesis, diagnostics and treatment are summarized in this review.

Effect of new dietary supplement on sperm quality

2012 ◽  
Vol 153 (45) ◽  
pp. 1787-1792 ◽  
Author(s):  
Mária Horváth ◽  
Endre Czeizel
Keyword(s):  
Adverse Effect ◽  
Clinical Trial ◽  
Dietary Supplement ◽  
Male Fertility ◽  
Sperm Quality ◽  
Sperm Count ◽  
Before And After ◽  
The Usa ◽  
New Treatments

Introduction: There is a decline in male fertility thus new treatments are needed. Aims: To test the efficacy of a new dietary supplement developed in the USA and registered as a curing drug in Hungary (OGYI). Methods: In a clinical trial 100 men with low sperm quality (spermium count 5–20 M/ml, good motility 10–40%, and adverse shape 30–50%) were examined. Results: Sperm parameters were measured before and after a 3-month treatment and after another 3-month without treatment. This dietary supplement statistically and clinically significantly improved sperm count and motility. In 74 cases this dietary supplement demonstrated a beneficial effect on sperm quality (more than 10% increase in sperm count, or quality of motility, or shape); in 16 cases the improvement exceeded 30%. No adverse effect could be accounted for this treatment. Conclusions: This new dietary supplement may contribute to the treatment of male infertility. Orv. Hetil., 2012, 153, 1787–1792.

Visual Merchandising and Customers’ Impulse Buying Behavior: A Case of a Fashion Specialty Store

2020 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
Hadijah Iberahim ◽  
Nur Amira Zureena Zulkurnain ◽  
Raja Najwa Syamim Raja Ainal Shah ◽  
Siti Quraisyiah Rosli
Keyword(s):  
Adverse Effect ◽  
Statistical Data ◽  
Impulse Buying ◽  
Kuala Lumpur ◽  
Statistical Data Analysis ◽  
Buying Behavior ◽  
Specialty Store ◽  
Research Outcome ◽  
Five Elements ◽  
Visual Merchandising

Visual merchandising is an extremely important element as the first visual cue that affects buying behavior of customers. This study aims to identify determinants of visual merchandising that influence customers’ impulse buying behavior. This study focuses on five elements of visual merchandising which are window display, mannequin display, floor merchandising, promotional signage and lighting. Investigation was conducted at a popular fashion specialty store in Kuala Lumpur, Malaysia. A total of 150 customers' feedback was collected. Results of statistical data analysis show that three out of five visual merchandising elements are important in influencing the customers’ impulse buying behavior. Window display, mannequin display and promotional signage are positively related and identified as determinants of effective visual merchandising for impulse buying decision at the women fashion specialty store. The research outcome extends understanding on the adverse effect of visual merchandising on customers’ behavior.

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