Calculation of Crystal Habit and Solvent-Accessible Areas of Sucrose and Adipic Acid Crystals

1990 ◽  
pp. 55-71 ◽  
Author(s):  
Allan S. Myerson ◽  
Michael Saska
Keyword(s):  
Adipic Acid ◽  
Crystal Habit

Antibacterial Activity of Biodegradable Particles based on Chitosan Containing Colloidal Silver

2020 ◽  
Vol 36 (4) ◽  
pp. 87-93
Author(s):  
V.Yu. Reshetova ◽  
A.F. Krivoshchepov ◽  
I.A. Butorova ◽  
N.B. Feldman ◽  
S.V. Lutsenko ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Antibacterial Activity ◽  
Polymer Matrix ◽  
Adipic Acid ◽  
Antibacterial Effect ◽  
Academic Excellence ◽  
Colloidal Silver ◽  
Scanning Electron Microscopy Data ◽  
Covalent Bonds ◽  
Agar Diffusion Test

Chitosan beads with colloidal silver nanoparticles inclued in the polymer matrix have been obtained by the introduction of chitosan into an acidified nanosilver sol. Dual interconnection of drops of the resulting solution was then carried out by ionotropic gelation at the first stage and covalent crosslinking of the polymer matrix with adipic acid at the second stage. The surface morphology of the obtained beads was studied by scanning electron microscopy. Data of Fourier transform IR spectroscopy confirmed the formation of covalent bonds between chitosan and adipic acid. The antibacterial activity of obtained beads against S. aureus and E. coli was evaluated using agar diffusion test. It was shown that the сhitosan beads modified with nanostructured silver exhibited an antibacterial effect against the tested strains, and they can be used as a basis for creating biodegradable wound healing dressings with a prolonged antibacterial effect. chitosan, silver nanoparticles, antibacterial activity, wound dressings This work was supported by the "Russian Academic Excellence Project 5-100". The study was carried out with the financial support of the Russian Foundation for Basic Research in the framework of the Scientific Project no. 18-29-18039.

Insight into Delivery Approaches for Biopharmaceutics Classification System Class II and IV Drugs

2020 ◽  
Vol 10 (4) ◽  
pp. 255-277
Author(s):  
Shashank Chaturvedi ◽  
Raghav Mishra
Keyword(s):  
Class Ii ◽  
Crystal Habit ◽  
Extensive Literature ◽  
Formulation Development ◽  
Particle Size Reduction ◽  
Bioavailability Enhancement ◽  
Poor Solubility ◽  
Biopharmaceutics Classification System Class ◽  
Poorly Soluble ◽  
Physical And Chemical

: Formulation development of BCS Class II and IV drugs is a challenging task due to their poor solubility and permeability issue. : An extensive literature survey was conducted to explore the relevant pharmaceutical approaches that have been used for solving the issue of poor solubility and permeability in the recent past. : It has been found that a plethora of approaches have been investigated for addressing the issue of poor solubility and or permeability. These include physical modifications (modification of crystal habit, particle size reduction, complexation, polymorphism and drug dispersion in carriers), chemical modifications (salt formation), and formulation modifications (Nanotechnology-based approaches and hydrotropy). : The physical and chemical modification approaches can be effectively used to enhance the solubility and dissolution rate of poorly soluble drugs, but the additional problem of poor permeability has been better addressed by lipid-based drug delivery systems. As the latter presents the drug in the solubilized state, bypass first-pass effects, circumvent the effect of Para-glycoprotein mediated efflux of drugs, hence contributing to overall bioavailability enhancement.

scholarly journals Designing of Green Plasticizers and Assessment of the Effectiveness of Their Use

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1761
Author(s):  
Aliya K. Mazitova ◽  
Guliya K. Aminova ◽  
Irina N. Vikhareva
Keyword(s):  
Adipic Acid ◽  
Polymer Materials ◽  
Operational Parameters ◽  
Solid Domestic Waste ◽  
Polymer Waste ◽  
Synthetic Materials ◽  
Environmental Requirements ◽  
Potential Methods ◽  
High Set ◽  
Acid Esters

The growing anthropogenic load on the lithosphere is currently characterized by the alienation of huge areas for solid domestic waste. One of the most common pollutants is traditional plastics with a degradation period of over 100 years. In connection with the increasing environmental requirements, polymer materials, along with a high set of technological and operational parameters, must be environmentally friendly and biodegradable. The development of polymer composite materials that undergo accelerated physicochemical and biological changes in the natural environment due to the introduction of biodegradable additives is one of the potential methods for processing synthetic materials and ensures the release of significant areas of fertile soils and lands from the steadily increasing amount of polymer waste. The use of adipic acid esters as PVC plasticizers contributes to the production of biodegradable composites. The article describes a method for obtaining new esters of adipic acid, presents the results of studying their properties for practical use in PVC composites, and assesses the economic efficiency of preventing damage to the environment when using them.

Hydroxyl-terminated carbon dots for efficient conversion of cyclohexane to adipic acid

2021 ◽  
Vol 591 ◽  
pp. 281-289 ◽  
Author(s):  
Xiao Wang ◽  
Wenyi Bian ◽  
Yurong Ma ◽  
Yan Liu ◽  
Zhenzhen Wang ◽  
...  
Keyword(s):  
Adipic Acid ◽  
Carbon Dots ◽  
Efficient Conversion

scholarly journals An Insight into Chemistry and Structure of Colloidal 2D-WS2 Nanoflakes: Combined XPS and XRD Study

Nanomaterials ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1969
Author(s):  
Riccardo Scarfiello ◽  
Elisabetta Mazzotta ◽  
Davide Altamura ◽  
Concetta Nobile ◽  
Rosanna Mastria ◽  
...  
Keyword(s):  
Photoelectron Spectroscopy ◽  
Xrd Analysis ◽  
Crystal Habit ◽  
Phase Identification ◽  
X Ray Diffraction ◽  
X Ray ◽  
Morphological Evaluation ◽  
Rational Understanding ◽  
Structural Inspection

The surface and structural characterization techniques of three atom-thick bi-dimensional 2D-WS2 colloidal nanocrystals cross the limit of bulk investigation, offering the possibility of simultaneous phase identification, structural-to-morphological evaluation, and surface chemical description. In the present study, we report a rational understanding based on X-ray photoelectron spectroscopy (XPS) and structural inspection of two kinds of dimensionally controllable 2D-WS2 colloidal nanoflakes (NFLs) generated with a surfactant assisted non-hydrolytic route. The qualitative and quantitative determination of 1T’ and 2H phases based on W 4f XPS signal components, together with the presence of two kinds of sulfur ions, S22− and S2−, based on S 2p signal and related to the formation of WS2 and WOxSy in a mixed oxygen-sulfur environment, are carefully reported and discussed for both nanocrystals breeds. The XPS results are used as an input for detailed X-ray Diffraction (XRD) analysis allowing for a clear discrimination of NFLs crystal habit, and an estimation of the exact number of atomic monolayers composing the 2D-WS2 nanocrystalline samples.

Two-Stage Temperature Control for the Synthesis of Adipic Acid through K/A Oil Oxidation in a Microreactor System

2021 ◽  
Author(s):  
Guangxiao Li ◽  
Saier Liu ◽  
Xiaoyong Dou ◽  
Minjing Shang ◽  
Zheng-Hong Luo ◽  
...  
Keyword(s):  
Temperature Control ◽  
Adipic Acid ◽  
Oil Oxidation ◽  
Two Stage
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