The Glycine1Residue in Cyclic Lactam Analogues of Galanin(1−16)-NH2Is Important for Stabilizing an N-Terminal Helix

Biochemistry ◽  
1999 ◽  
Vol 38 (46) ◽  
pp. 15295-15304 ◽  
Author(s):  
Katharine A. Carpenter ◽  
Ralf Schmidt ◽  
Shi Yi Yue ◽  
Lejla Hodzic ◽  
Chantevy Pou ◽  
...  
Keyword(s):  
Cyclic Lactam

Design, Synthesis, and Biological Activities of Cyclic Lactam Peptide Analogues of Dynorphin A(1−11)-NH21

1996 ◽  
Vol 39 (5) ◽  
pp. 1136-1141 ◽  
Author(s):  
Feng-Di T. Lung ◽  
Nathan Collins ◽  
Dagmar Stropova ◽  
Peg Davis ◽  
Henry I. Yamamura ◽  
...  
Keyword(s):  
Biological Activities ◽  
Dynorphin A ◽  
Design Synthesis ◽  
Peptide Analogues ◽  
Cyclic Lactam

Synthesis and biological activities of cyclic lactam peptides as substrates for non-receptors PTKs

1999 ◽  
Vol 6 (2-3) ◽  
pp. 117-121
Author(s):  
Paolo Ruzza ◽  
Arianna Donella-Deana ◽  
Andrea Calderan ◽  
Barbara Biondi ◽  
Lorenzo A. Pinna ◽  
...  
Keyword(s):  
Biological Activities ◽  
Cyclic Lactam

Kinetics of degradation of a cyclic lactam analog of α-melanotropin (MT-II) in aqueous solution

1994 ◽  
Vol 102 (1-3) ◽  
pp. 193-199 ◽  
Author(s):  
Sydney O. Ugwu ◽  
En-Ling Lan ◽  
Shubh Sharma ◽  
Victor Hruby ◽  
James Blanchard
Keyword(s):  
Aqueous Solution ◽  
Kinetics Of Degradation ◽  
Kinetics Of ◽  
Cyclic Lactam

Infrared Absorption Spectra and Polymeric Structures of Three s-Triazine Herbicides and Their Metabolites

1967 ◽  
Vol 50 (3) ◽  
pp. 595-600
Author(s):  
J-Y T Chen
Keyword(s):  
Hydrogen Bonding ◽  
Infrared Absorption ◽  
Triazine Herbicides ◽  
Amino Groups ◽  
Keto Form ◽  
Metabolic Products ◽  
Infrared Absorption Spectra ◽  
Absorption Frequencies ◽  
Polymeric Structures ◽  
Cyclic Lactam

Abstract The infrared spectra of three 2-chloro- 4,6-bis (alkylamino) s-triazincs and their metabolites in solid (KBr) phase are described, and the characteristic infrared absorption frequencies are given. These compounds may -exist as dimers in the solid state when hydrogen bonding occurs through one or both of the amino groups. In addition, the metabolic products, 2-hydroxy derivatives, may also exist as dimers by hydrogen bonding of the enol (OH) to the keto tautomers in equilibrium. Evidently the weak NH hydrogen bonding of the cis cyclic lactam dimer is partially depolymerized when the compound is ground in an adequate amount of Nujol, and the equilibrium shifts to yield the dimer resulting from strong hydrogen bonding of the enol (OH) to the keto form of the tautomers

Potent and prolonged-acting cyclic lactam analogs of .alpha.-melanotropin: design based on molecular dynamics

1989 ◽  
Vol 32 (12) ◽  
pp. 2555-2561 ◽  
Author(s):  
Fahad Al-Obeidi ◽  
Ana M. de L. Castrucci ◽  
Mac E. Hadley ◽  
Victor J. Hruby
Keyword(s):  
Molecular Dynamics ◽  
Cyclic Lactam

Synthesis and biological activities of fatty acid conjugates of a cyclic lactam .alpha.-melanotropin

1992 ◽  
Vol 35 (1) ◽  
pp. 118-123 ◽  
Author(s):  
Fahad Al-Obeidi ◽  
Victor J. Hruby ◽  
Nader Yaghoubi ◽  
Mohamed M. Marwan ◽  
Mac E. Hadley
Keyword(s):  
Fatty Acid ◽  
Biological Activities ◽  
Cyclic Lactam

scholarly journals Cyclic lactam hybrid α-MSH/Agouti-related protein (AGRP) analogues with nanomolar range binding affinities at the human melanocortin receptors

2011 ◽  
Vol 21 (10) ◽  
pp. 3099-3102 ◽  
Author(s):  
Alexander V. Mayorov ◽  
Minying Cai ◽  
Erin S. Palmer ◽  
Dustin K. Tanaka ◽  
James P. Cain ◽  
...  
Keyword(s):  
Melanocortin Receptors ◽  
Binding Affinities ◽  
Related Protein ◽  
Agouti Related Protein ◽  
Nanomolar Range ◽  
Cyclic Lactam

Cyclic lactam analogs of the α-factor from saccharomyces cerevisiae

Peptides ◽  
1994 ◽  
pp. 430-432 ◽  
Author(s):  
W. Yang ◽  
X. Rao ◽  
O. Antohi ◽  
H. F. Lu ◽  
A. Mckinney ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Cyclic Lactam
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