Transition State of the Rate-Limiting Step of Heat Denaturation of Cry3A δ-Endotoxin†

Sergey A. Potekhin; Olga I. Loseva; Elizabeth I. Tiktopulo; Anatoly P. Dobritsa

doi:10.1021/bi982789k

Transition State of the Rate-Limiting Step of Heat Denaturation of Cry3A δ-Endotoxin†

Biochemistry ◽

10.1021/bi982789k ◽

1999 ◽

Vol 38 (13) ◽

pp. 4121-4127 ◽

Cited By ~ 15

Author(s):

Sergey A. Potekhin ◽

Olga I. Loseva ◽

Elizabeth I. Tiktopulo ◽

Anatoly P. Dobritsa

Keyword(s):

Transition State ◽

Heat Denaturation ◽

Rate Limiting Step ◽

Limiting Step ◽

Rate Limiting

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DFT study of phenol alkylation with propylene on H-BEA in the absence and presence of water

Reaction Chemistry & Engineering ◽

10.1039/d1re00201e ◽

2021 ◽

Author(s):

Sajal Kanti Dutta ◽

Vishal Agarwal

Keyword(s):

Transition State ◽

Transition State Theory ◽

Rate Coefficient ◽

Activation Barrier ◽

State Theory ◽

Dft Study ◽

Phenol Alkylation ◽

Rate Limiting Step ◽

Limiting Step ◽

Rate Limiting

Water reduces the activation barrier of the rate-limiting step of phenol alkylation with propylene in H-BEA. This, in turn, increases the transition-state theory rate coefficient by two orders-of-magnitude, suggesting much faster alkylation.

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Thermodynamic Properties of the Transition State for the Rate-Limiting Step in the Folding of the .alpha. Subunit of Tryptophan Synthase

Biochemistry ◽

10.1021/bi00186a040 ◽

1994 ◽

Vol 33 (20) ◽

pp. 6356-6362 ◽

Cited By ~ 22

Author(s):

Xiaowu Chen ◽

C. Robert Matthews

Keyword(s):

Thermodynamic Properties ◽

Transition State ◽

Alpha Subunit ◽

Tryptophan Synthase ◽

Rate Limiting Step ◽

Limiting Step ◽

Rate Limiting

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Studies of the rate-limiting step in the tyrosine hydroxylase reaction: alternate substrates, solvent isotope effects, and transition-state analogs

Biochemistry ◽

10.1021/bi00240a006 ◽

1991 ◽

Vol 30 (26) ◽

pp. 6386-6391 ◽

Cited By ~ 35

Author(s):

Paul F. Fitzpatrick

Keyword(s):

Tyrosine Hydroxylase ◽

Transition State ◽

Isotope Effects ◽

Transition State Analogs ◽

Rate Limiting Step ◽

Limiting Step ◽

Solvent Isotope ◽

Rate Limiting ◽

Solvent Isotope Effects

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Transition state and rate-limiting step of the reaction catalyzed by the human dual-specificity phosphatase, VHR

Biochemistry ◽

10.1021/bi00049a024 ◽

1995 ◽

Vol 34 (49) ◽

pp. 16088-16096 ◽

Cited By ~ 24

Author(s):

Zhong-Yin Zhang ◽

Li Wu ◽

Li Chen

Keyword(s):

Transition State ◽

Dual Specificity Phosphatase ◽

Rate Limiting Step ◽

Limiting Step ◽

Dual Specificity ◽

Rate Limiting

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Solid products and rate-limiting step in the thermal half decomposition of natural dolomite in a CO2(g) atmosphere

Thermochimica Acta ◽

10.1016/s0040-6031(02)00603-2 ◽

2003 ◽

Cited By ~ 1

Author(s):

D Beruto

Keyword(s):

Rate Limiting Step ◽

Limiting Step ◽

Rate Limiting

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Ornithine Decarboxylase Activity in Cultured Endothelial Cells Stimulated by Serum, Thrombin and Serotonin

Thrombosis and Haemostasis ◽

10.1055/s-0038-1646709 ◽

1978 ◽

Vol 39 (02) ◽

pp. 496-503 ◽

Cited By ~ 8

Author(s):

P A D’Amore ◽

H B Hechtman ◽

D Shepro

Keyword(s):

Endothelial Cells ◽

Ornithine Decarboxylase ◽

Decarboxylase Activity ◽

Aortic Endothelial Cells ◽

Ornithine Decarboxylase Activity ◽

Rate Limiting Step ◽

Bovine Aortic Endothelial Cells ◽

Limiting Step ◽

Rate Limiting ◽

Serum Serotonin

SummaryOrnithine decarboxylase (ODC) activity, the rate-limiting step in the synthesis of polyamines, can be demonstrated in cultured, bovine, aortic endothelial cells (EC). Serum, serotonin and thrombin produce a rise in ODC activity. The serotonin-induced ODC activity is significantly blocked by imipramine (10-5 M) or Lilly 11 0140 (10-6M). Preincubation of EC with these blockers together almost completely depresses the 5-HT-stimulated ODC activity. These observations suggest a manner by which platelets may maintain EC structural and metabolic soundness.

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