Determinants of Ligand Binding to cAMP-Dependent Protein Kinase†

Philippe H. Hünenberger; Volkhard Helms; Narendra Narayana; Susan S. Taylor; J. Andrew McCammon

doi:10.1021/bi982064g

Determinants of Ligand Binding to cAMP-Dependent Protein Kinase†

Biochemistry ◽

10.1021/bi982064g ◽

1999 ◽

Vol 38 (8) ◽

pp. 2358-2366 ◽

Cited By ~ 55

Author(s):

Philippe H. Hünenberger ◽

Volkhard Helms ◽

Narendra Narayana ◽

Susan S. Taylor ◽

J. Andrew McCammon

Keyword(s):

Protein Kinase ◽

Ligand Binding ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Calculating pKa values in the cAMP-dependent protein kinase: The effect of conformational change and ligand binding

Protein Science ◽

10.1002/pro.530 ◽

2010 ◽

Vol 19 (12) ◽

pp. 2485-2497 ◽

Cited By ~ 4

Author(s):

Una Bjarnadottir ◽

Jens Erik Nielsen

Keyword(s):

Protein Kinase ◽

Ligand Binding ◽

Conformational Change ◽

Dependent Protein Kinase ◽

Pka Values ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Circular dichroic evidence for an ordered sequence of ligand/binding site interactions in the catalytic reaction of the cAMP-dependent protein kinase

Biochemistry ◽

10.1021/bi00333a024 ◽

1985 ◽

Vol 24 (12) ◽

pp. 2967-2973 ◽

Cited By ~ 39

Author(s):

Jennifer Reed ◽

Volker Kinzel ◽

Bruce E. Kemp ◽

Hueng Chin Cheng ◽

Donal A. Walsh

Keyword(s):

Protein Kinase ◽

Ligand Binding ◽

Binding Site ◽

Catalytic Reaction ◽

Ligand Binding Site ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein ◽

Circular Dichroic

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cAMP exerts proliferative and anti-proliferative effects in pituitary cells of different types by activating both cAMP-dependent protein kinase A and exchange proteins directly activated by cAMP

Endocrine Abstracts ◽

10.1530/endoabs.32.p827 ◽

2013 ◽

Author(s):

Eleonora Vitali ◽

Erika Peverelli ◽

Giovanna Mantovani ◽

Elena Giardino ◽

Andrea G. Lania ◽

...

Keyword(s):

Protein Kinase ◽

Protein Kinase A ◽

Pituitary Cells ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Different Types ◽

Dependent Protein ◽

Kinase A

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Faculty Opinions recommendation of Distal recognition sites in substrates are required for efficient phosphorylation by the cAMP-dependent protein kinase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1165205.628140 ◽

2009 ◽

Author(s):

Jonathan Chernoff

Keyword(s):

Protein Kinase ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Recognition Sites ◽

Dependent Protein

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Faculty Opinions recommendation of Differential regulation of CaV1.2 channels by cAMP-dependent protein kinase bound to A-kinase anchoring proteins 15 and 79/150.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718291698.793492090 ◽

2014 ◽

Author(s):

Johannes Hell

Keyword(s):

Protein Kinase ◽

Differential Regulation ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Anchoring Proteins ◽

Dependent Protein ◽

Cav1.2 Channels

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Rapid and reversible translocation of the catalytic subunit of cAMP-dependent protein kinase type II from the Golgi complex to the nucleus.

The EMBO Journal ◽

10.1002/j.1460-2075.1985.tb04006.x ◽

1985 ◽

Vol 4 (11) ◽

pp. 2801-2806 ◽

Cited By ~ 217

Author(s):

E.A. Nigg ◽

H. Hilz ◽

H.M. Eppenberger ◽

F. Dutly

Keyword(s):

Protein Kinase ◽

Golgi Complex ◽

Catalytic Subunit ◽

Type Ii ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Thalamocortical projections have a K+ channel that is phosphorylated and modulated by cAMP-dependent protein kinase

Journal of Neuroscience ◽

10.1523/jneurosci.15-08-05486.1995 ◽

1995 ◽

Vol 15 (8) ◽

pp. 5486-5501 ◽

Cited By ~ 48

Author(s):

H Moreno ◽

C Kentros ◽

E Bueno ◽

M Weiser ◽

A Hernandez ◽

...

Keyword(s):

Protein Kinase ◽

K Channel ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Thalamocortical Projections ◽

Dependent Protein

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Dephosphorylation of cAMP-dependent protein kinase regulatory subunit (type II) by calmodulin-dependent protein phosphatase. Determinants of substrate specificity.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)83888-7 ◽

1986 ◽

Vol 261 (18) ◽

pp. 8140-8145 ◽

Cited By ~ 1

Author(s):

D K Blumenthal ◽

K Takio ◽

R S Hansen ◽

E G Krebs

Keyword(s):

Protein Kinase ◽

Substrate Specificity ◽

Protein Phosphatase ◽

Regulatory Subunit ◽

Type Ii ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Glutamic acid 203 of the cAMP-dependent protein kinase catalytic subunit participates in the inhibition by two isoforms of the protein kinase inhibitor.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)42170-3 ◽

1994 ◽

Vol 269 (3) ◽

pp. 2316-2323

Author(s):

E.J. Baude ◽

S.S. Dignam ◽

S.R. Olsen ◽

E.M. Reimann ◽

M.D. Uhler

Keyword(s):

Protein Kinase ◽

Glutamic Acid ◽

Kinase Inhibitor ◽

Protein Kinase Inhibitor ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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Neutral cholesterol esterase activity in macrophages and its enhancement by cAMP-dependent protein kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)42944-4 ◽

1981 ◽

Vol 256 (24) ◽

pp. 12659-12661 ◽

Cited By ~ 11

Author(s):

J.C. Khoo ◽

E.M. Mahoney ◽

D Steinberg

Keyword(s):

Protein Kinase ◽

Esterase Activity ◽

Cholesterol Esterase ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

Dependent Protein

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