Thermodynamics of dT−dT Base Pair Mismatching in Linear DNA Duplexes and Three-Arm DNA Junctions†

Biochemistry ◽  
1997 ◽  
Vol 36 (9) ◽  
pp. 2485-2491 ◽  
Author(s):  
Min Zhong ◽  
Luis A. Marky ◽  
Neville R. Kallenbach ◽  
Donald W. Kupke
Keyword(s):  
Base Pair ◽  
Dna Duplexes ◽  
Linear Dna ◽  
Dna Junctions

Excess Electron Transfer through DNA Duplexes Comprising a Metal‐Mediated Base Pair

2017 ◽  
Vol 23 (43) ◽  
pp. 10244-10248 ◽  
Author(s):  
Susanne Hensel ◽  
Kevin Eckey ◽  
Philipp Scharf ◽  
Nicole Megger ◽  
Uwe Karst ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Base Pair ◽  
Excess Electron ◽  
Dna Duplexes

Targeting in linear DNA duplexes with two complementary probe strands for hybrid stability

1993 ◽  
Vol 3 (4) ◽  
pp. 365-372 ◽  
Author(s):  
Elissa P. Sena ◽  
David A. Zarling
Keyword(s):  
Dna Duplexes ◽  
Linear Dna

End-to-End Stacking and Liquid Crystal Condensation of 6- to 20-Base Pair DNA Duplexes

Science ◽  
2007 ◽  
Vol 318 (5854) ◽  
pp. 1276-1279 ◽  
Author(s):  
M. Nakata ◽  
G. Zanchetta ◽  
B. D. Chapman ◽  
C. D. Jones ◽  
J. O. Cross ◽  
...  
Keyword(s):  
Liquid Crystal ◽  
Base Pair ◽  
Dna Duplexes ◽  
End To End

scholarly journals Enzymatic Formation of an Artificial Base Pair Using a Modified Adenine Nucleoside Triphosphate

2019 ◽  
Author(s):  
Marie Flamme ◽  
Pascal Röthlisberger ◽  
Fabienne Levi-Acobas ◽  
Mohit Chawla ◽  
Romina Oliva ◽  
...  
Keyword(s):  
Base Pair ◽  
In Vitro Selection ◽  
Solid Phase ◽  
Nucleoside Triphosphate ◽  
Dna Duplexes ◽  
Base Pairs ◽  
Metal Base ◽  
Enzymatic Formation ◽  
Genetic Alphabet

The expansion of the genetic alphabet with additional, unnatural base pairs (UBPs) is an important and long standing goal in synthetic biology. Nucleotides acting as ligands for the coordination of metal cations have advanced as promising candidates for such an expansion of the genetic alphabet. However,the inclusion of artificial metal base pairs in nucleic acids mainly relies on solid-phase synthesis approaches and very little is known on polymerase-mediated synthesis. Herein, we report on the selective and high yielding enzymatic construction of a silver-mediated base pair as well as a two-step protocol for the synthesis of DNA duplexes containing a metal UBP. Guided by DFT calculations, we also shed light into the mechanism of formation of this UBP as well as into the structural and energetic preferences. Even though this silver UBP is not directly amenable to in vitro selection experiments, the enzymatic synthesis of this UBP provides valuable insights for the design of future, more potent systems aiming at expanding the genetic alphabet. <br>

Additional Base-Pair Formation in DNA Duplexes by a Double-Headed Nucleotide

2012 ◽  
Vol 18 (24) ◽  
pp. 7434-7442 ◽  
Author(s):  
Charlotte S. Madsen ◽  
Sarah Witzke ◽  
Pawan Kumar ◽  
Kushuma Negi ◽  
Pawan K. Sharma ◽  
...  
Keyword(s):  
Base Pair ◽  
Pair Formation ◽  
Dna Duplexes ◽  
Additional Base

Frontispiece: Excess Electron Transfer through DNA Duplexes Comprising a Metal‐Mediated Base Pair

2017 ◽  
Vol 23 (43) ◽  
Author(s):  
Susanne Hensel ◽  
Kevin Eckey ◽  
Philipp Scharf ◽  
Nicole Megger ◽  
Uwe Karst ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Base Pair ◽  
Excess Electron ◽  
Dna Duplexes

scholarly journals Substrate properties of 25-nt parallel-stranded linear DNA duplexes

Biochemistry ◽  
1989 ◽  
Vol 28 (24) ◽  
pp. 9542-9549 ◽  
Author(s):  
Karsten Rippe ◽  
Thomas M. Jovin
Keyword(s):  
Dna Duplexes ◽  
Linear Dna ◽  
Substrate Properties

scholarly journals Spectroscopic properties and helical stabilities of 25-nt parallel-stranded linear DNA duplexes

Biochemistry ◽  
1989 ◽  
Vol 28 (24) ◽  
pp. 9536-9541 ◽  
Author(s):  
Karsten Rippe ◽  
Niels B. Ramsing ◽  
Thomas M. Jovin
Keyword(s):  
Spectroscopic Properties ◽  
Dna Duplexes ◽  
Linear Dna
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