scholarly journals Altered Enthalpy−Entropy Compensation in Picomolar Transition State Analogues of Human Purine Nucleoside Phosphorylase

Biochemistry ◽  
2009 ◽  
Vol 48 (23) ◽  
pp. 5226-5238 ◽  
Author(s):  
Achelle A. Edwards ◽  
Jennifer M. Mason ◽  
Keith Clinch ◽  
Peter C. Tyler ◽  
Gary B. Evans ◽  
...  
Keyword(s):  
Transition State ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogues

scholarly journals Conformational States of Human Purine Nucleoside Phosphorylase at Rest, at Work, and with Transition State Analogues

Biochemistry ◽  
2010 ◽  
Vol 49 (9) ◽  
pp. 2058-2067 ◽  
Author(s):  
Achelle A. Edwards ◽  
Jeremiah D. Tipton ◽  
Michael D. Brenowitz ◽  
Mark R. Emmett ◽  
Alan G. Marshall ◽  
...  
Keyword(s):  
Transition State ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Conformational States ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogues

Synthesis of Second-Generation Transition State Analogues of Human Purine Nucleoside Phosphorylase

2003 ◽  
Vol 46 (24) ◽  
pp. 5271-5276 ◽  
Author(s):  
Gary B. Evans ◽  
Richard H. Furneaux ◽  
Andrzej Lewandowicz ◽  
Vern L. Schramm ◽  
Peter C. Tyler
Keyword(s):  
Transition State ◽  
Second Generation ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogues

scholarly journals Four generations of transition-state analogues for human purine nucleoside phosphorylase

2010 ◽  
Vol 107 (11) ◽  
pp. 4805-4812 ◽  
Author(s):  
M.-C. Ho ◽  
W. Shi ◽  
A. Rinaldo-Matthis ◽  
P. C. Tyler ◽  
G. B. Evans ◽  
...  
Keyword(s):  
Transition State ◽  
Purine Nucleoside Phosphorylase ◽  
Purine Nucleoside ◽  
Nucleoside Phosphorylase ◽  
Transition State Analogues
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