A 1.9 Å Crystal Structure of the HDV Ribozyme Precleavage Suggests both Lewis Acid and General Acid Mechanisms Contribute to Phosphodiester Cleavage

Biochemistry ◽  
2010 ◽  
Vol 49 (31) ◽  
pp. 6508-6518 ◽  
Author(s):  
Jui-Hui Chen ◽  
Rieko Yajima ◽  
Durga M. Chadalavada ◽  
Elaine Chase ◽  
Philip C. Bevilacqua ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Lewis Acid ◽  
General Acid ◽  
Hdv Ribozyme ◽  
Phosphodiester Cleavage

Methansulfinylchlorid-Lewissäure-Addukte CH3S(Cl)OMF5 (M = As, Sb) und Kristallstruktur von CH3S(Cl)OSbCl5 [1] / Methanesulfinylchloride Lewis Acid Adducts CH3S(Cl)OMF5 (M = As, Sb) and Crystal Structure of CH3S(Cl)OSbCl5 [1]

1996 ◽  
Vol 51 (1) ◽  
pp. 133-138 ◽  
Author(s):  
Rolf Minkwitz ◽  
Ulrike Lohmann ◽  
Hans Preut
Keyword(s):  
Crystal Structure ◽  
Nmr Spectroscopy ◽  
Lewis Acid ◽  
Unit Cell ◽  
Monoclinic Space Group ◽  
Space Group ◽  
New Compounds ◽  
Lewis Acid Adducts

Abstract CH3S(0)C1 reacts in HF as solvent with MF5 (M = As, Sb) to give products CH3S(Cl)OMF5 (M = As, Sb). The new compounds are stable below 253 K and were charac­ terized by Raman and NMR spectroscopy.In addition, the crystal structure of CH3S(Cl)OSbCl5 has been determinated. The complex crystallizes in the monoclinic space group P21/n with a = 644.3(5), b = 1905.9(14), c = 900.0(7) pm, β = 99.27(6)° with four formula units per unit cell.

scholarly journals First Total Synthesis and Investigation of the X-ray Crystal Structure of the Pyrano[3,2-a]carbazole Alkaloid Clausenalansine A

Synthesis ◽  
2020 ◽  
Vol 53 (02) ◽  
pp. 359-364
Author(s):  
Hans-Joachim Knölker ◽  
Valerie Lösle ◽  
Olga Kataeva
Keyword(s):  
Crystal Structure ◽  
Total Synthesis ◽  
Lewis Acid ◽  
Oxidative Cyclization ◽  
Formyl Group ◽  
Pyran Ring ◽  
X Ray ◽  
Synthetic Strategy

AbstractWe describe the first total synthesis of the recently discovered pyrano[3,2-a]carbazole alkaloid clausenalansine A. The synthetic strategy for the construction of this formylpyrano[3,2-a]carbazole is based on a sequence of Buchwald–Hartwig coupling, palladium(II)-catalyzed oxidative cyclization, Lewis acid promoted annulation of the pyran ring, and chemoselective oxidation of a methyl to a formyl group.

The isolation and crystal structure of the powerful Lewis acid, planar tetrakispyridine cobalt(II), [Co(C5H5N)4]2+, as its mixed chloride hexafluorophosphate salt

Polyhedron ◽  
1996 ◽  
Vol 15 (3) ◽  
pp. 473-479 ◽  
Author(s):  
James K. Beattie ◽  
Trevor W. Hambley ◽  
John A. Klepetko ◽  
Anthony F. Masters ◽  
Peter Turner
Keyword(s):  
Crystal Structure ◽  
Lewis Acid

ChemInform Abstract: Efficient Intramolecular General Acid Catalysis: A Preview from a Crystal Structure.

ChemInform ◽  
2010 ◽  
Vol 33 (11) ◽  
pp. no-no
Author(s):  
Andrew D. Bond ◽  
Anthony J. Kirby ◽  
Encina Rodriguez
Keyword(s):  
Crystal Structure ◽  
Acid Catalysis ◽  
General Acid

Orthoamide, LXVII [1]. Bis(diformylamino)methan – ein neues leistungsfähiges Formylierungsmittel für aromatische Verbindungen / Orthoamides, LXVII [1]. Bis(diformylamino)methane – a New Efficient Formylating Reagent for Aromatic Compounds

2008 ◽  
Vol 63 (4) ◽  
pp. 395-406 ◽  
Author(s):  
Willi Kantlehner ◽  
Ernst Anders ◽  
Jochen Mezger ◽  
Edmont V. Stoyanov ◽  
Ralf Kreß ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Lewis Acid ◽  
Structure Determination ◽  
Aromatic Compounds ◽  
Lewis Acids ◽  
Crystal Structure Determination ◽  
Pyridinium Chloride ◽  
Guanidinium Salt

AbstractFormaldehyde reacts with diformamide (10) to give N-(hydroxymethyl)diformamide (11), which upon treatment with thionylchloride yields N-(chlormethyl)diformamide (12) together with small amounts of oxydimethylenebis(diformamide) (13). Various diformylamine derivatives, such as diformylaminomethyl formiate (14), diformylaminomethylisothiocyanate (15) and the N-diformylaminomethylated guanidinium salt 16, can be prepared from 12. Bis(diformylamino) methane (7) can be obtained by the reaction of sodium diformamide (8) with either 1-(chloromethyl)pyridinium chloride (9) or N-(chloromethyl)diformamide (12) in acetonitrile. The action of tris(chloromethyl) amine (18) on sodium diformamide (8) affords tris(diformylaminomethyl)amine (19). The constitution of the compounds 7, 11 and 19 was confirmed by crystal structure determination. The nature of the products from the reactions of aromatic compounds with 12 depends on the Lewis acid which is used as activator. Thus the N-benzylformamides 20a, b can be obtained from toluene and mesitylene and 12/BF3-ether, whereas 1,2,4-trimethoxybenzene is formylated by 12/AlCl3 to give the aldehyde 22. Interestingly enough, a novel and efficient formylating reagent resulted from these investigations: bis(diformylamino)methane (7), which can be activated by Lewis acids, e. g. AlCl3. The scope of this procedure is comparable with that of the Olah-formylation method (formylfluoride/BF3).

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