Calorimetric Studies of Ligand Binding in R67 Dihydrofolate Reductase†

Biochemistry ◽  
2005 ◽  
Vol 44 (37) ◽  
pp. 12420-12433 ◽  
Author(s):  
Michael Jackson ◽  
Shaileja Chopra ◽  
R. Derike Smiley ◽  
Patrick O'Neal Maynord ◽  
Andre Rosowsky ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Dihydrofolate Reductase ◽  
R67 Dihydrofolate Reductase ◽  
Calorimetric Studies

Role of Ionic Interactions in Ligand Binding and Catalysis of R67 Dihydrofolate Reductase†

Biochemistry ◽  
2003 ◽  
Vol 42 (36) ◽  
pp. 10569-10578 ◽  
Author(s):  
Stephanie N. Hicks ◽  
R. Derike Smiley ◽  
J. Bradley Hamilton ◽  
Elizabeth E. Howell
Keyword(s):  
Ligand Binding ◽  
Dihydrofolate Reductase ◽  
Ionic Interactions ◽  
R67 Dihydrofolate Reductase

scholarly journals “Catch 222,” the Effects of Symmetry on Ligand Binding and Catalysis in R67 Dihydrofolate Reductase as Determined by Mutations at Tyr-69

2004 ◽  
Vol 279 (45) ◽  
pp. 47003-47009 ◽  
Author(s):  
Lori G. Stinnett ◽  
R. Derike Smiley ◽  
Stephanie N. Hicks ◽  
Elizabeth E. Howell
Keyword(s):  
Ligand Binding ◽  
Dihydrofolate Reductase ◽  
R67 Dihydrofolate Reductase

Multiple ligand-binding modes in bacterial R67 dihydrofolate reductase

2005 ◽  
Vol 19 (3) ◽  
pp. 165-187 ◽  
Author(s):  
Hernán Alonso ◽  
Malcolm B. Gillies ◽  
Peter L. Cummins ◽  
Andrey A. Bliznyuk ◽  
Jill E. Gready
Keyword(s):  
Ligand Binding ◽  
Dihydrofolate Reductase ◽  
Binding Modes ◽  
R67 Dihydrofolate Reductase ◽  
Multiple Ligand

Does R67 Dihydrofolate Reductase Possess a Proton Donor?

1993 ◽  
pp. 493-498 ◽  
Author(s):  
Janel C. Holland ◽  
Charles E. Linn ◽  
Enrico DiGiammarino ◽  
Robert Nichols ◽  
Elizabeth E. Howell
Keyword(s):  
Dihydrofolate Reductase ◽  
Proton Donor ◽  
R67 Dihydrofolate Reductase

scholarly journals Role of Lys-32 Residues in R67 Dihydrofolate Reductase Probed by Asymmetric Mutations

2004 ◽  
Vol 279 (45) ◽  
pp. 46995-47002 ◽  
Author(s):  
Stephanie N. Hicks ◽  
R. Derike Smiley ◽  
Lori G. Stinnett ◽  
Kenneth H. Minor ◽  
Elizabeth E. Howell
Keyword(s):  
Dihydrofolate Reductase ◽  
R67 Dihydrofolate Reductase

Structure and energetics of ligand binding to proteins:Escherichia coli dihydrofolate reductase-trimethoprim, a drug-receptor system

1988 ◽  
Vol 4 (1) ◽  
pp. 31-47 ◽  
Author(s):  
Pnina Dauber-Osguthorpe ◽  
Victoria A. Roberts ◽  
David J. Osguthorpe ◽  
Jon Wolff ◽  
Moniqe Genest ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Dihydrofolate Reductase ◽  
Receptor System ◽  
Drug Receptor

Further Studies on the Role of Water in R67 Dihydrofolate Reductase

Biochemistry ◽  
2013 ◽  
Vol 52 (12) ◽  
pp. 2118-2127 ◽  
Author(s):  
Mary Jane Timson ◽  
Michael R. Duff ◽  
Greyson Dickey ◽  
Arnold M. Saxton ◽  
José I. Reyes-De-Corcuera ◽  
...  
Keyword(s):  
Dihydrofolate Reductase ◽  
R67 Dihydrofolate Reductase
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