Portability of Epimerization Domain and Role of Peptidyl Carrier Protein on Epimerization Activity in Nonribosomal Peptide Synthetases†

Uwe Linne; Sascha Doekel; Mohamed A. Marahiel

doi:10.1021/bi011595t

Portability of Epimerization Domain and Role of Peptidyl Carrier Protein on Epimerization Activity in Nonribosomal Peptide Synthetases†

Biochemistry ◽

10.1021/bi011595t ◽

2001 ◽

Vol 40 (51) ◽

pp. 15824-15834 ◽

Cited By ~ 63

Author(s):

Uwe Linne ◽

Sascha Doekel ◽

Mohamed A. Marahiel

Keyword(s):

Carrier Protein ◽

Nonribosomal Peptide ◽

Nonribosomal Peptide Synthetases ◽

Peptide Synthetases

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Biochemical evidence for conformational changes in the cross-talk between adenylation and peptidyl-carrier protein domains of nonribosomal peptide synthetases

FEBS Journal ◽

10.1111/j.1742-4658.2009.07551.x ◽

2010 ◽

Vol 277 (5) ◽

pp. 1159-1171 ◽

Cited By ~ 13

Author(s):

Joachim Zettler ◽

Henning D. Mootz

Keyword(s):

Conformational Changes ◽

Cross Talk ◽

Protein Domains ◽

Carrier Protein ◽

Nonribosomal Peptide ◽

Biochemical Evidence ◽

Nonribosomal Peptide Synthetases ◽

Peptide Synthetases ◽

The Cross

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Intermediary conformations linked to the directionality of the aminoacylation pathway of nonribosomal peptide synthetases

RSC Chemical Biology ◽

10.1039/d0cb00220h ◽

2021 ◽

Author(s):

Florian Mayerthaler ◽

Anna-Lena Feldberg ◽

Jonas Alfermann ◽

Xun Sun ◽

Wieland Steinchen ◽

...

Keyword(s):

Conformational Changes ◽

Protein Domains ◽

Carrier Protein ◽

Nonribosomal Peptide ◽

Nonribosomal Peptide Synthetases ◽

Peptide Synthetases

In-solution analysis of conformational changes of NRPS adenylation and peptidyl-carrier protein domains under catalytic conditions reveals a new intermediary conformation.

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The Stress-Responsive and Host-Oriented Role of Nonribosomal Peptide Synthetases in an Entomopathogenic Fungus, Beauveria bassiana

Journal of Microbiology and Biotechnology ◽

10.4014/jmb.1606.06056 ◽

2017 ◽

Vol 27 (3) ◽

pp. 439-449 ◽

Cited By ~ 1

Author(s):

Hang Liu ◽

Linan Xie ◽

Jing Wang ◽

Qiannan Guo ◽

Shengnan Yang ◽

...

Keyword(s):

Beauveria Bassiana ◽

Entomopathogenic Fungus ◽

Nonribosomal Peptide ◽

Nonribosomal Peptide Synthetases ◽

Peptide Synthetases ◽

Fungus Beauveria Bassiana

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Analysis of the linker region joining the adenylation and carrier protein domains of the modular nonribosomal peptide synthetases

Proteins Structure Function and Bioinformatics ◽

10.1002/prot.24635 ◽

2014 ◽

Vol 82 (10) ◽

pp. 2691-2702 ◽

Cited By ~ 26

Author(s):

Bradley R. Miller ◽

Jesse A. Sundlov ◽

Eric J. Drake ◽

Thomas A. Makin ◽

Andrew M. Gulick

Keyword(s):

Protein Domains ◽

Carrier Protein ◽

Nonribosomal Peptide ◽

Linker Region ◽

Nonribosomal Peptide Synthetases ◽

Peptide Synthetases

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Carrier Protein Recognition in Siderophore-Producing Nonribosomal Peptide Synthetases†

Biochemistry ◽

10.1021/bi0202575 ◽

2002 ◽

Vol 41 (26) ◽

pp. 8429-8437 ◽

Cited By ~ 20

Author(s):

C. Gary Marshall ◽

Michael D. Burkart ◽

Robin K. Meray ◽

Christopher T. Walsh

Keyword(s):

Protein Recognition ◽

Carrier Protein ◽

Nonribosomal Peptide ◽

Nonribosomal Peptide Synthetases ◽

Peptide Synthetases

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A chemical proteomic probe for detecting native carrier protein motifs in nonribosomal peptide synthetases

Chemical Communications ◽

10.1039/c6cc07793e ◽

2016 ◽

Vol 52 (98) ◽

pp. 14129-14132 ◽

Cited By ~ 5

Author(s):

Shota Kasai ◽

Fumihiro Ishikawa ◽

Takehiro Suzuki ◽

Naoshi Dohmae ◽

Hideaki Kakeya

Keyword(s):

Carrier Protein ◽

Nonribosomal Peptide ◽

Nonribosomal Peptide Synthetases ◽

Protein Motifs ◽

Peptide Synthetases

An activity-based probe coupled to a 5′-(vinylsulfonylaminodeoxy)adenosine scaffold with a clickable alkyne functionality selectively targets native carrier protein motifs in nonribosomal peptide synthetases.

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