Biosynthesis of Cyclopropane Compounds. VI. Product Inhibition of Cyclopropane Fatty Acid Synthetase by S-Adenosylhomocysteine and Reversal of Inhibition by a Hydrolytic Enzyme*

Biochemistry ◽  
1964 ◽  
Vol 3 (12) ◽  
pp. 1989-1993 ◽  
Author(s):  
Albert E. Chung ◽  
John H. Law
Keyword(s):  
Fatty Acid ◽  
Hydrolytic Enzyme ◽  
Fatty Acid Synthetase ◽  
Product Inhibition ◽  
Cyclopropane Fatty Acid

scholarly journals Functional Analysis of Leishmania Cyclopropane Fatty Acid Synthetase

PLoS ONE ◽  
2012 ◽  
Vol 7 (12) ◽  
pp. e51300 ◽  
Author(s):  
Samuel O. Oyola ◽  
Krystal J. Evans ◽  
Terry K. Smith ◽  
Barbara A. Smith ◽  
James D. Hilley ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Fatty Acid ◽  
Fatty Acid Synthetase ◽  
Cyclopropane Fatty Acid

Lipid biosynthesis during the recovery of Salmonella typhimurium from thermal injury

1972 ◽  
Vol 18 (7) ◽  
pp. 1015-1021 ◽  
Author(s):  
Richard I. Tomlins ◽  
Gloria L. Vaaler ◽  
Z. John Ordal
Keyword(s):  
Fatty Acid ◽  
Salmonella Typhimurium ◽  
Total Lipid ◽  
Recovery Period ◽  
Fatty Acid Synthetase ◽  
Cyclopropane Fatty Acid ◽  
Normal Cells ◽  
Isotope Dilution Assay ◽  
Cyclopropane Fatty Acids ◽  
Fatty Acid Species

The heating of Salmonella typhimurium 7136 at 48C produced a sublethal injury. When injured cells were placed in fresh growth medium, they recovered within 3 h their normal tolerance to Levine Eosin Methylene Blue Agar containing 2% NaCl (EMBS). An isotope dilution assay demonstrated that 26.6% of the total lipid extracted from recovered cells was synthesized during the recovery period. Phospholipids synthesized during growth or recovery comprised about 90% of the total lipid. The concentrations of phosphatidyl ethanolamine and phosphatidyl glycerol synthesized during growth or recovery were similar; however, the amount of cardiolipin synthesized during recovery was greater than that obtained from normal cells. The fatty acid species synthesized during recovery were qualitatively similar but quantitatively dissimilar to the fatty acid profile of normal cells. The decreased concentrations of cyclopropane fatty acids with concomitant increases in their parent monoenoic acids gave presumptive evidence for the partial inactivation during injury of the enzyme cyclopropane fatty acid synthetase.

scholarly journals Goose fatty acid synthetase mRNA.

1980 ◽  
Vol 255 (20) ◽  
pp. 9519-9522 ◽  
Author(s):  
Z.E. Zehner ◽  
J.S. Mattick ◽  
R. Stuart ◽  
S.J. Wakil
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Synthetase
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