Studies on the secondary structure of phenylalanyl transfer ribonucleic acid

Biochemistry ◽  
1970 ◽  
Vol 9 (25) ◽  
pp. 4971-4980 ◽  
Author(s):  
Alita Rosenfeld ◽  
Charles L. Stevens ◽  
Morton P. Printz
Nature ◽  
1959 ◽  
Vol 184 (4689) ◽  
pp. 818-819 ◽  
Author(s):  
R. A. COX ◽  
U. Z. LITTAUER

1970 ◽  
Vol 117 (1) ◽  
pp. 101-118 ◽  
Author(s):  
R. A. Cox

The spectrum of RNA from the smaller and larger subparticles of rabbit reticulocyte ribosomes was studied as a function of pH, ionic strength, urea concentration and temperature. It was inferred that both RNA species form short double-helical segments of not more than about 10 base-pairs in length. Not more than about 70% of the base residues may be located in double-helical segments. RNA from the larger subparticle is richer in guanine and cytosine residues and its secondary structure is the more stable. These conclusions are based on the use of double-helical RNA from virus-like particles and of unfractionated Escherichia coli tRNA as model systems.


1972 ◽  
Vol 9 (6) ◽  
pp. 903-908 ◽  
Author(s):  
Dean L. Engelhardt

1973 ◽  
Vol 135 (2) ◽  
pp. 349-351 ◽  
Author(s):  
A. A. Hadjiolov ◽  
R. A. Cox

The spectrophotometric analysis of 45S precursor rRNA shows that it contains more G and C residues than does mature 28S or 18S rRNA. The helical content and the length of double-helical segments in 45S and 28S rRNA are similar.


1973 ◽  
Vol 135 (1) ◽  
pp. 237-240 ◽  
Author(s):  
Christopher J. Leaver

The majority of chloroplast 1.1X106-mol.wt. rRNA molecules are nicked at specific points in the polynucleotide chain, the molecules being kept intact at low temperatures by their secondary structure. Conditions that break hydrogen bonds and lead to loss of secondary structure cause dissociation of the molecule.


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