Ribonucleic acid directed deoxyribonucleic acid synthesis by the purified deoxyribonucleic acid polymerase of Rous sarcoma virus. Characterization of the enzymic product

Biochemistry ◽  
1972 ◽  
Vol 11 (12) ◽  
pp. 2343-2351 ◽  
Author(s):  
J. M. Taylor ◽  
A. J. Faras ◽  
H. E. Varmus ◽  
W. E. Levinson ◽  
J. M. Bishop
Keyword(s):  
Ribonucleic Acid ◽  
Rous Sarcoma Virus ◽  
Deoxyribonucleic Acid ◽  
Acid Synthesis ◽  
Rous Sarcoma ◽  
Deoxyribonucleic Acid Synthesis ◽  
Sarcoma Virus

scholarly journals Deoxyribonucleic Acid Polymerase of Rous Sarcoma Virus: Studies on the Mechanism of Double-Stranded Deoxyribonucleic Acid Synthesis

1971 ◽  
Vol 7 (5) ◽  
pp. 539-548 ◽  
Author(s):  
Anthony Faras ◽  
Lois Fanshier ◽  
Axel-Claude Garapin ◽  
Warren Levinson ◽  
J. Michael Bishop
Keyword(s):  
Rous Sarcoma Virus ◽  
Deoxyribonucleic Acid ◽  
Acid Synthesis ◽  
Rous Sarcoma ◽  
Deoxyribonucleic Acid Synthesis ◽  
Sarcoma Virus

scholarly journals Deoxyribonucleic Acid Polymerases of Rous Sarcoma Virus: Kinetics of Deoxyribonucleic Acid Synthesis and Specificity of the Products

1971 ◽  
Vol 7 (2) ◽  
pp. 227-232 ◽  
Author(s):  
Axel-Claude Garapin ◽  
Lois Fanshier ◽  
Jo-Ann Leong ◽  
Jean Jackson ◽  
Warren Levinson ◽  
...  
Keyword(s):  
Rous Sarcoma Virus ◽  
Deoxyribonucleic Acid ◽  
Acid Synthesis ◽  
Rous Sarcoma ◽  
Deoxyribonucleic Acid Synthesis ◽  
Sarcoma Virus ◽  
Kinetics Of

Induction of cellular deoxyribonucleic acid synthesis in butyrate-treated cells by simian virus 40 deoxyribonucleic acid

1981 ◽  
Vol 1 (11) ◽  
pp. 1038-1047
Author(s):  
S Kawasaki ◽  
L Diamond ◽  
R Baserga
Keyword(s):  
Ribonucleic Acid ◽  
Deoxyribonucleic Acid ◽  
Simian Virus 40 ◽  
Acid Synthesis ◽  
Simian Virus ◽  
S Phase ◽  
Temperature Sensitive ◽  
3T3 Cells ◽  
Deoxyribonucleic Acid Synthesis ◽  
G1 Cells

Sodium butyrate (3 mM) inhibited the entry into the S phase of quiescent 3T3 cells stimulated by serum, but had no effect on the accumulation of cellular ribonucleic acid. Simian virus 40 infection or manual microinjection of cloned fragments from the simian virus 40 A gene caused quiescent 3T3 cells to enter the S phase even in the presence of butyrate. NGI cells, a line of 3T3 cells transformed by simian virus 40, grew vigorously in 3 mM butyrate. Homokaryons were formed between G1 and S-phase 3T3 cells, Butyrate inhibited the induction of deoxyribonucleic acid synthesis that usually occurs in B1 nuclei when G1 cells are fused with S-phase cells. However, when G1 3T3 cells were fused with exponentially growing NGI cells, the 3T3 nuclei were induced to enter deoxyribonucleic acid synthesis. In tsAF8 cells, a ribonucleic acid polymerase II mutant that stops in the G1 phase of the cell cycle, no temporal sequence was demonstrated between the butyrate block and the temperature-sensitive block. These results confirm previous reports that certain virally coded proteins can induce cell deoxyribonucleic acid synthesis in the absence of cellular functions that are required by serum-stimulated cells. Our interpretation of these data is that butyrate inhibited cell growth by inhibiting the expression of genes required for the G0 leads to G1 leads to S transition and that the product of the simian virus 40 A gene overrode this inhibition by providing all of the necessary functions for the entry into the S phase.

scholarly journals Characterization of the genomic RNA from a Rous sarcoma virus mutant temperature sensitive for cell transformation

1979 ◽  
Vol 6 (2) ◽  
pp. 471-486 ◽  
Author(s):  
Jean-Luc Darlix ◽  
Mireille Levray ◽  
Peter A. Bromley ◽  
Pierre-François Spahr
Keyword(s):  
Rous Sarcoma Virus ◽  
Cell Transformation ◽  
Temperature Sensitive ◽  
Genomic Rna ◽  
Rous Sarcoma ◽  
Sarcoma Virus ◽  
Virus Mutant
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