Kinetics of association between bisquaternary ammonium ligands and acetylcholinesterase. Evidence for two conformational states of the enzyme from stopped-flow measurements of fluorescence

Biochemistry ◽  
1979 ◽  
Vol 18 (16) ◽  
pp. 3622-3629 ◽  
Author(s):  
Michael B. Bolger ◽  
Palmer Taylor
Keyword(s):  
Stopped Flow ◽  
Conformational States ◽  
Flow Measurements ◽  
Kinetics Of

scholarly journals Binding Kinetics of 4-Methylumbelliferyl alpha-Mannobioside to Concanavalin A by Fluorescence Stopped-Flow Measurements

1980 ◽  
Vol 103 (2) ◽  
pp. 313-321 ◽  
Author(s):  
Anita LANDSCHOOT ◽  
Frank G. LOONTIENS ◽  
Robert M. CLEGG ◽  
Thomas M. JOVIN
Keyword(s):  
Concanavalin A ◽  
Binding Kinetics ◽  
Stopped Flow ◽  
Flow Measurements ◽  
Kinetics Of

Kinetics of Formation of Vesicles from Lecithin/Sodium Xylenesulfonate Micelles from Stopped-Flow Measurements

Langmuir ◽  
1998 ◽  
Vol 14 (3) ◽  
pp. 590-594 ◽  
Author(s):  
Samuel E. Campbell ◽  
Zhiqiang Zhang ◽  
Stig E. Friberg ◽  
Ramesh Patel
Keyword(s):  
Stopped Flow ◽  
Flow Measurements ◽  
Kinetics Of Formation ◽  
Kinetics Of

scholarly journals Study on the initial kinetics of yeast phosphofructokinase by stopped-flow measurements

1986 ◽  
Vol 156 (2) ◽  
pp. 311-315 ◽  
Author(s):  
Jorg BAR ◽  
Gerhard HUBNER ◽  
Gerhard KOPPERSCHLAGER
Keyword(s):  
Stopped Flow ◽  
Flow Measurements ◽  
Kinetics Of

Stopped-flow and Brownian dynamics studies of electrostatic effects in the kinetics of binding of 7-methyl-GpppG to the protein eIF4E

2000 ◽  
Vol 29 (7) ◽  
pp. 487-498 ◽  
Author(s):  
E. Błachut-Okrasińska ◽  
E. Bojarska ◽  
A. Niedźwiecka ◽  
L. Chlebicka ◽  
E. Darżynkiewicz ◽  
...  
Keyword(s):  
Brownian Dynamics ◽  
Stopped Flow ◽  
Electrostatic Effects ◽  
Kinetics Of

The mechanism of the oxidation of thiocyanate ion by peroxomonosulphate in aqueous solution. II. Kinetics of the reaction

1966 ◽  
Vol 19 (8) ◽  
pp. 1365 ◽  
Author(s):  
RH Smith ◽  
IR Wilson
Keyword(s):  
Aqueous Solution ◽  
Initial Rate ◽  
Stopped Flow ◽  
Thiocyanate Ion ◽  
First Order ◽  
Conductance Method ◽  
Rate Of Reaction ◽  
Kinetics Of

Initial rates of reaction for the above oxidation have been measured by a stopped-flow conductance method. Between pH 2 and 3.6, the initial rate of reaction, R, is given by the expression R{[HSO5-]+[SCN-]} = {kb+kc[H+]}[HSO5-]0[SCN-]20+ka[H+]-1[HSO5]20[SCN-]0 As pH increases, there is a transition to a pH-independent rate, first order in each thiocyanate and peroxomonosulphate concentrations.

scholarly journals Metal Enolates – Enamines – Enol Ethers: How Do Enolate Equivalents Differ in Nucleophilic Reactivity?

Synthesis ◽  
2019 ◽  
Vol 51 (05) ◽  
pp. 1157-1170 ◽  
Author(s):  
Artem Leonov ◽  
Daria Timofeeva ◽  
Armin Ofial ◽  
Herbert Mayr
Keyword(s):  
Rate Constants ◽  
Correlation Equation ◽  
Stopped Flow ◽  
Quinone Methides ◽  
Enol Ethers ◽  
Reactivity Descriptors ◽  
Silyl Enol Ethers ◽  
Nucleophilic Reactivity ◽  
Kinetics Of ◽  
Least Squares Minimization

The kinetics of the reactions of trimethylsilyl enol ethers and enamines (derived from deoxybenzoin, indane-1-one, and α-tetralone) with reference electrophiles (p-quinone methides, benzhydrylium and indolylbenzylium ions) were measured by conventional and stopped-flow photometry in acetonitrile at 20 °C. The resulting second-order rate constants were subjected to a least-squares minimization based on the correlation equation lg k = s N(N + E) for determining the reactivity descriptors N and s N of the silyl enol ethers and enamines. The relative reactivities of structurally analogous silyl enol ethers, enamines, and enolate anions towards carbon-centered electrophiles are determined as 1, 107, and 1014, respectively. A survey of synthetic applications of enolate ions and their synthetic equivalents shows that their behavior can be properly described by their nucleophilicity parameters, which therefore can be used for designing novel synthetic transformations.

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