Evidence that hydride transfer precedes proton transfer in the liver alcohol dehydrogenase catalyzed reduction of trans-4-(N,N-dimethylamino)cinnamaldehyde

Biochemistry ◽  
1980 ◽  
Vol 19 (4) ◽  
pp. 725-731 ◽  
Author(s):  
Richard G. Morris ◽  
Gerald Saliman ◽  
Michael F. Dunn
Keyword(s):  
Alcohol Dehydrogenase ◽  
Proton Transfer ◽  
Hydride Transfer ◽  
Liver Alcohol Dehydrogenase

Hydride Transfer in Liver Alcohol Dehydrogenase:  Quantum Dynamics, Kinetic Isotope Effects, and Role of Enzyme Motion

2001 ◽  
Vol 123 (45) ◽  
pp. 11262-11272 ◽  
Author(s):  
Salomon R. Billeter ◽  
Simon P. Webb ◽  
Pratul K. Agarwal ◽  
Tzvetelin Iordanov ◽  
Sharon Hammes-Schiffer
Keyword(s):  
Alcohol Dehydrogenase ◽  
Quantum Dynamics ◽  
Isotope Effects ◽  
Hydride Transfer ◽  
Kinetic Isotope Effects ◽  
Liver Alcohol Dehydrogenase ◽  
Kinetic Isotope

EXAFS INVESTIGATION OF THE STRUCTURAL SITE OF LIVER ALCOHOL DEHYDROGENASE

1986 ◽  
Vol 47 (C8) ◽  
pp. C8-1165-C8-1168
Author(s):  
M. ZEPPEZAUER ◽  
C. HAAS ◽  
W. MARET ◽  
C. HERMES ◽  
R. F. PETTIFER
Keyword(s):  
Alcohol Dehydrogenase ◽  
Liver Alcohol Dehydrogenase ◽  
Structural Site
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