Nuclear magnetic resonance study of the state of protonation of inhibitors bound to mutant dihydrofolate reductase lacking the active-site carboxyl

Biochemistry ◽  
1986 ◽  
Vol 25 (22) ◽  
pp. 7229-7235 ◽  
Author(s):  
Robert E. London ◽  
Elizabeth E. Howell ◽  
Mark S. Warren ◽  
Joseph Kraut ◽  
Raymond L. Blakley
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Dihydrofolate Reductase ◽  
Active Site ◽  
Nuclear Magnetic Resonance Study ◽  
The State ◽  
Magnetic Resonance Study ◽  
Nuclear Magnetic

Carbon-13 nuclear magnetic resonance study of protonation of methotrexate and aminopterin bound to dihydrofolate reductase

Biochemistry ◽  
1981 ◽  
Vol 20 (14) ◽  
pp. 3972-3978 ◽  
Author(s):  
Lennie Cocco ◽  
John P. Groff ◽  
Carroll Temple ◽  
John A. Montgomery ◽  
Robert E. London ◽  
...  
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Dihydrofolate Reductase ◽  
Nuclear Magnetic Resonance Study ◽  
Magnetic Resonance Study ◽  
Nuclear Magnetic
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