Stimulation of deoxyribonucleic acid excision repair in human fibroblasts pretreated with sodium butyrate

Biochemistry ◽  
1985 ◽  
Vol 24 (24) ◽  
pp. 6861-6869 ◽  
Author(s):  
Steven L. Dresler
Keyword(s):  
Sodium Butyrate ◽  
Deoxyribonucleic Acid ◽  
Excision Repair ◽  
Human Fibroblasts ◽  
Stimulation Of

Permeabilization of ultraviolet-irradiated Chinese hamster cells with polyethylene glycol and introduction of ultraviolet endonuclease from Micrococcus luteus

1981 ◽  
Vol 1 (3) ◽  
pp. 237-244
Author(s):  
D B Yarosh ◽  
R B Setlow
Keyword(s):  
Polyethylene Glycol ◽  
Deoxyribonucleic Acid ◽  
Excision Repair ◽  
Micrococcus Luteus ◽  
Chinese Hamster ◽  
Endonuclease Activity ◽  
Chinese Hamster Cells ◽  
Ultraviolet Resistance

Chinese hamster V-79 cells were made permeable by treatment with polyethylene glycol and then incubated with a Micrococcus luteus extract containing ultraviolet-specific endonuclease activity. This treatment introduced nicks in irradiated, but not in unirradiated, deoxyribonucleic acid. The nicks remained open for at least 3 h; there was no loss of endonuclease-sensitive sites, and no excision of dimers as measured by chromatography was detected. In addition, there was no increase in ultraviolet resistance in treated cells. This suggests that the absence of a significant amount of excision repair in rodent cells is due to the lack of both incision and excision capacity.

Enzymatic Studies of Base Excision Repair in Cultured Human Fibroblasts and in Escherichia coli

1981 ◽  
pp. 97-112 ◽  
Author(s):  
Stuart Linn ◽  
Bruce Demple ◽  
Dale W. Mosbaugh ◽  
Huber R. Warner ◽  
Walter A. Deutsch
Keyword(s):  
Escherichia Coli ◽  
Base Excision Repair ◽  
Excision Repair ◽  
Human Fibroblasts ◽  
Cultured Human Fibroblasts ◽  
Base Excision
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