Low-ultraviolet circular dichroism spectroscopy of oligopeptides 1-95 and 96-168 derived from myelin basic protein of rabbit

Biochemistry ◽  
1985 ◽  
Vol 24 (23) ◽  
pp. 6666-6673 ◽  
Author(s):  
Audrey Larack Stone ◽  
Juliana Y. Park ◽  
Russell E. Martenson
Keyword(s):  
Circular Dichroism ◽  
Myelin Basic Protein ◽  
Basic Protein ◽  
Circular Dichroism Spectroscopy ◽  
Circular Dichroïsm

scholarly journals Biophysical characterization of 21.5-kDa myelin basic protein (MBP) and the effects of zinc on its structure

SURG Journal ◽  
2014 ◽  
Vol 7 (3) ◽  
pp. 30-41
Author(s):  
Danielle K. Lanthier ◽  
Kenrick A. Vassall ◽  
George Harauz
Keyword(s):  
Circular Dichroism ◽  
Fluorescence Spectroscopy ◽  
Myelin Basic Protein ◽  
Basic Protein ◽  
Critical Role ◽  
Intrinsically Disordered Protein ◽  
Biophysical Characterization ◽  
Intrinsically Disordered ◽  
Circular Dichroïsm

Myelin Basic Protein (MBP) is a highly abundant protein in central nervous system (CNS) myelin that has a critical role in its proper formation and functioning. The 21.5-kDa isoform of MBP has been shown to be selectively imported into the nucleus of myelin-producing cells, oligodendrocytes, and may be involved in signaling pathways that affect the formation and recovery of CNS myelin. The first step in understanding potential nuclear binding partners of 21.5-kDa MBP is to characterize the structure of the protein. In this study, circular dichroism and fluorescence spectroscopy were used to analyze the structure of 21.5-kDa rmMBP (recombinant murine MBP) in vitro in the presence and absence of Zn2+, an abundant trace metal in CNS myelin that has been suggested to affect MBP structure. Fluorescence spectroscopy with a probe for hydrophobic protein regions showed that Zn2+ may affect the conformation of 21.5-kDa MBP in aqueous solution. Keywords: myelin basic protein (MBP); intrinsically-disordered protein; circular dichroism; fluoresence spectroscopy

scholarly journals Conformation Transition Kinetics of Silk Fibroin in Aqueous Solution Explored Using Circular Dichroism Spectroscopy

2021 ◽  
Vol 6 (8) ◽  
pp. 1735-1740
Author(s):  
Sora Lee ◽  
Soo Hyun Kim ◽  
You‐Young Jo ◽  
Wan‐Taek Ju ◽  
Hyun‐Bok Kim ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Circular Dichroism ◽  
Silk Fibroin ◽  
Circular Dichroism Spectroscopy ◽  
Kinetics Of ◽  
Circular Dichroïsm ◽  
Conformation Transition

Enantiopure methoxetamine stereoisomers: chiral resolution, conformational analysis, UV-circular dichroism spectroscopy and electronic circular dichroism

2021 ◽  
Author(s):  
Kun Won Lee ◽  
Ahmed H. E. Hassan ◽  
Youngdo Jeong ◽  
Seolmin Yoon ◽  
Seung-Hwan Kim ◽  
...  
Keyword(s):  
Circular Dichroism ◽  
Conformational Analysis ◽  
Absolute Configuration ◽  
Circular Dichroism Spectroscopy ◽  
Chiral Resolution ◽  
Treatment Resistant Depression ◽  
Treatment Resistant ◽  
Electronic Circular Dichroism ◽  
Resistant Depression ◽  
Circular Dichroïsm

Enantioseparation and assignment of absolute configuration of methoxetamine (MXE) enantiopure stereoisomers; a promising novel antidepressant for management of treatment-resistant depression.

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