Structural consequences of the natural substitution, E9K, on reactive-site-hydrolyzed squash (Cucurbita maxima) trypsin inhibitor (CMTI), as studied by two-dimensional NMR

Ramaswamy Krishnamoorthi; Chan Lan Sun Lin; David VanderVelde

doi:10.1021/bi00136a007

Structural consequences of the natural substitution, E9K, on reactive-site-hydrolyzed squash (Cucurbita maxima) trypsin inhibitor (CMTI), as studied by two-dimensional NMR

Biochemistry ◽

10.1021/bi00136a007 ◽

1992 ◽

Vol 31 (21) ◽

pp. 4965-4969 ◽

Cited By ~ 2

Author(s):

Ramaswamy Krishnamoorthi ◽

Chan Lan Sun Lin ◽

David VanderVelde

Keyword(s):

Trypsin Inhibitor ◽

Two Dimensional ◽

Cucurbita Maxima ◽

Reactive Site

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Two-dimensional NMR studies of squash family inhibitors. Sequence-specific proton assignments and secondary structure of reactive-site hydrolyzed Cucurbita maxima trypsin inhibitor III

Biochemistry ◽

10.1021/bi00118a036 ◽

1992 ◽

Vol 31 (3) ◽

pp. 898-904 ◽

Cited By ~ 7

Author(s):

Ramaswamy Krishnamoorthi ◽

Yu Xi Gong ◽

Chan Lan Sun Lin ◽

David VanderVelde

Keyword(s):

Secondary Structure ◽

Trypsin Inhibitor ◽

Two Dimensional ◽

Cucurbita Maxima ◽

Reactive Site ◽

Nmr Studies

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Natural abundance 15 N NMR assignments delineate structural differences between intact and reactive-site hydrolyzed Cucurbita maxima trypsin inhibitor III

FEBS Letters ◽

10.1016/0014-5793(92)80607-i ◽

1992 ◽

Vol 304 (2-3) ◽

pp. 149-152 ◽

Cited By ~ 1

Author(s):

Ramaswamy Krishnamoorthi ◽

Sylvia Nemmers ◽

Brian Tobias

Keyword(s):

Trypsin Inhibitor ◽

Nmr Assignments ◽

Natural Abundance ◽

Cucurbita Maxima ◽

Reactive Site ◽

Structural Differences

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Reactive-Site Hydrolyzed Cucurbita maxima Trypsin Inhibitor-V: Function, Thermodynamic Stability, and NMR Solution Structure

Biochemistry ◽

10.1021/bi00038a001 ◽

1995 ◽

Vol 34 (38) ◽

pp. 12087-12094 ◽

Cited By ~ 8

Author(s):

Mengli Cai ◽

YuXi Gong ◽

Om Prakash ◽

Ramaswamy Krishnamoorthi

Keyword(s):

Trypsin Inhibitor ◽

Thermodynamic Stability ◽

Solution Structure ◽

Cucurbita Maxima ◽

Reactive Site ◽

Nmr Solution Structure

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NMR studies of internal dynamics of serine proteinase protein inhibitors: Binding region mobilities of intact and reactive-site hydrolyzed Cucurbita maxima trypsin inhibitor (CMTI)-III of the squash family and comparison with those of counterparts of CMTI

Protein Science ◽

10.1002/pro.5560070114 ◽

1998 ◽

Vol 7 (1) ◽

pp. 132-141 ◽

Cited By ~ 10

Author(s):

Jianhua Liu ◽

Yuxi Gong ◽

Om Prakash ◽

Ramaswamy Krishnamoorthi ◽

Lisa Wen ◽

...

Keyword(s):

Trypsin Inhibitor ◽

Serine Proteinase ◽

Cucurbita Maxima ◽

Reactive Site ◽

Binding Region ◽

Protein Inhibitors ◽

Nmr Studies ◽

Internal Dynamics

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Examples of Peptide-Peptoid Hybrid Serine Protease Inhibitors Based on the Trypsin Inhibitor SFTI-1 with Complete Protease Resistance at the P1P1′ Reactive Site

ChemBioChem ◽

10.1002/cbic.200400412 ◽

2005 ◽

Vol 6 (6) ◽

pp. 1057-1061 ◽

Cited By ~ 34

Author(s):

Maciej Stawikowski ◽

Roma Stawikowska ◽

Anna Jaśkiewicz ◽

Ewa Zabłotna ◽

Krzysztof Rolka

Keyword(s):

Serine Protease ◽

Protease Inhibitors ◽

Trypsin Inhibitor ◽

Serine Protease Inhibitors ◽

Reactive Site ◽

Protease Resistance

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Amide Proton Exchange and Surface Conformation of the Basic Pancreatic Trypsin Inhibitor in Solution: Studies with Two-dimensional Nuclear Magnetic Resonance

NMR in Structural Biology - World Scientific Series in 20th Century Chemistry ◽

10.1142/9789812795830_0048 ◽

1995 ◽

pp. 540-558 ◽

Cited By ~ 1

Author(s):

GERHARD WAGNER ◽

KURT WÜTHRICH

Keyword(s):

Nuclear Magnetic Resonance ◽

Magnetic Resonance ◽

Trypsin Inhibitor ◽

Proton Exchange ◽

Amide Proton ◽

Two Dimensional ◽

Amide Proton Exchange ◽

Solution Studies ◽

Pancreatic Trypsin Inhibitor ◽

Surface Conformation

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Identification of the Reactive Site of Ascidian Trypsin Inhibitor

The Journal of Biochemistry ◽

10.1093/oxfordjournals.jbchem.a124597 ◽

1994 ◽

Vol 116 (4) ◽

pp. 787-793 ◽

Cited By ~ 1

Author(s):

Takashi Kumazaki ◽

Shin-ichi Ishii ◽

Hideyoshi Yokosawa

Keyword(s):

Trypsin Inhibitor ◽

Reactive Site

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Studies on the Reactive Site towards Chymotrypsin and Trypsin of the Basic Trypsin Inhibitor of Bovine Pancreas

Proceedings of the International Research Conference on Proteinase Inhibitors, Munich, November 4–6, 1970 ◽

10.1515/9783111508146-012 ◽

1971 ◽

pp. 74-88

Author(s):

Meir Rigbi ◽

M. Laskowski

Keyword(s):

Trypsin Inhibitor ◽

Reactive Site ◽

Bovine Pancreas

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Studies on Soybean Trypsin Inhibitors. 2. Amino-Acid Sequence around the Reactive Site of Soybean Trypsin Inhibitor (Kunitz)

European Journal of Biochemistry ◽

10.1111/j.1432-1033.1973.tb02623.x ◽

1973 ◽

Vol 32 (3) ◽

pp. 408-416 ◽

Cited By ~ 41

Author(s):

Takehiko Koide ◽

Tokuji IKENAKA ◽

Susumu Tsunasawa

Keyword(s):

Amino Acid ◽

Amino Acid Sequence ◽

Trypsin Inhibitor ◽

Trypsin Inhibitors ◽

Soybean Trypsin Inhibitor ◽

Reactive Site

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Purification and Quantification of Kunitz Trypsin Inhibitor in Soybean Using Two-Dimensional Liquid Chromatography

Food Analytical Methods ◽

10.1007/s12161-017-0902-6 ◽

2017 ◽

Vol 10 (10) ◽

pp. 3350-3360 ◽

Cited By ~ 12

Author(s):

Tianjiao Zhou ◽

Shuaijuan Han ◽

Zhen Li ◽

Pingli He

Keyword(s):

Liquid Chromatography ◽

Trypsin Inhibitor ◽

Two Dimensional ◽

Kunitz Trypsin Inhibitor

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