Calorimetric detection of influenza virus induced membrane fusion

Biochemistry ◽  
1995 ◽  
Vol 34 (17) ◽  
pp. 5705-5711 ◽  
Author(s):  
Simon Nebel ◽  
Ingrid Bartoldus ◽  
Toon Stegmann
Keyword(s):  
Influenza Virus ◽  
Membrane Fusion ◽  
Induced Membrane

Deacylation of influenza virus hemagglutinin does not affect the kinetics of low pH induced membrane fusion

1996 ◽  
Vol 431 (S6) ◽  
pp. R257-R258 ◽  
Author(s):  
Britta Schroth ◽  
Hans C. Philipp ◽  
Michael Veit ◽  
Michael F. G. Schmidt ◽  
Andreas Herrmann
Keyword(s):  
Influenza Virus ◽  
Membrane Fusion ◽  
Low Ph ◽  
Induced Membrane ◽  
Influenza Virus Hemagglutinin ◽  
Kinetics Of

scholarly journals Lipid interactions of the hemagglutinin HA2 NH2-terminal segment during influenza virus-induced membrane fusion.

1992 ◽  
Vol 267 (28) ◽  
pp. 20225-20232
Author(s):  
M Tsurudome ◽  
R Glück ◽  
R Graf ◽  
R Falchetto ◽  
U Schaller ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Membrane Fusion ◽  
Terminal Segment ◽  
Induced Membrane ◽  
Lipid Interactions

scholarly journals Influence of Salt Bridges in the Avian Influenza Virus HA on Acid-Induced Membrane Fusion and Pathogenicity

2012 ◽  
Vol 102 (3) ◽  
pp. 604a
Author(s):  
Caroline Mair ◽  
P. Sivaramakrishna Rachakonda ◽  
Thomas Korte ◽  
Andreas Herrmann
Keyword(s):  
Influenza Virus ◽  
Avian Influenza ◽  
Avian Influenza Virus ◽  
Membrane Fusion ◽  
Salt Bridges ◽  
Induced Membrane

An ultrastructural approach to influenza virus hemagglutinin-induced membrane fusion

1989 ◽  
Vol 31 (4) ◽  
pp. 460
Author(s):  
KoertN.J. Burger ◽  
Gerhard Knoll ◽  
Gerrit van Meer ◽  
ArieJ. Verkleij
Keyword(s):  
Influenza Virus ◽  
Membrane Fusion ◽  
Induced Membrane ◽  
Influenza Virus Hemagglutinin

scholarly journals Intermediates in influenza virus PR/8 haemagglutinin-induced membrane fusion

1994 ◽  
Vol 75 (2) ◽  
pp. 395-399 ◽  
Author(s):  
C. C. Pak ◽  
M. Krumbiegel ◽  
R. Blumenthal
Keyword(s):  
Influenza Virus ◽  
Membrane Fusion ◽  
Induced Membrane

scholarly journals Small Molecule Inhibitors of Influenza Virus Entry

2021 ◽  
Vol 14 (6) ◽  
pp. 587
Author(s):  
Zhaoyu Chen ◽  
Qinghua Cui ◽  
Michael Caffrey ◽  
Lijun Rong ◽  
Ruikun Du
Keyword(s):  
Influenza Virus ◽  
Membrane Fusion ◽  
Small Molecule ◽  
Drug Target ◽  
Small Molecule Inhibitors ◽  
Virus Entry ◽  
Critical Role ◽  
Structural Basis ◽  
Future Directions ◽  
The Past

Hemagglutinin (HA) plays a critical role during influenza virus receptor binding and subsequent membrane fusion process, thus HA has become a promising drug target. For the past several decades, we and other researchers have discovered a series of HA inhibitors mainly targeting its fusion machinery. In this review, we summarize the advances in HA-targeted development of small molecule inhibitors. Moreover, we discuss the structural basis and mode of action of these inhibitors, and speculate upon future directions toward more potent inhibitors of membrane fusion and potential anti-influenza drugs.

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